immunity News and Research

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Study identifies broad-spectrum antibody that neutralizes SARS-CoV-2 variants of concern

Scientists have described the identification and therapeutic evaluation of an antibody that broadly neutralizes major variants of SARS-CoV-2, including the alpha, beta, delta, and omicron variants.

5 Aug 2022

How does the flu vaccine affect the risk of contracting COVID-19?

A new study describes the association between the risk of contracting COVID-19 and the seasonal flu vaccine.

4 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

Researchers compared clinical outcomes of COVID-19 cases due to SARS-CoV-2 Omicron BA.2 and Omicron BA.4/BA.5 variants based on the Kaiser Permanente Southern California (KPSC) health records between April 29 and July 2, 2022.

4 Aug 2022

Disease progression in the rhesus macaque model upon inoculation with the Delta, Omicron BA.1, and Omicron BA.2 variants

Researchers compared the severity levels of disease caused by different SARS-CoV-2 variants of concern in the rhesus macaque model.

4 Aug 2022

Was there a benefit of vaccinating health care workers with a fourth dose of BNT162b2 vaccine during the Omicron outbreak?

Researchers analyzed the effectiveness of the fourth dose of the SARS-CoV-2 BNT162b2 vaccination against the SARS-CoV-2 Omicron infection in medical professionals in Israel.

4 Aug 2022

Epidemic model shows that intermediate levels of asymptomatic SARS-CoV-2 infection lead to the highest levels of epidemic fatalities

Researchers used a simplified epidemic model to demonstrate that asymptomatic SARS-CoV-2 infection leads to most fatalities.

4 Aug 2022

Study uses digital technology to evaluate antibody response following COVID-19 boosters

Researchers conducted an observational trial in the United States during the SARS-CoV-2 Omicron wave.

4 Aug 2022

Hybrid immunity retained six months after SARS-CoV-2 exposure

Scientists hypothesize that lower death rates in COVID-19 patients may be due to hybrid immunity, as well as the reduced severity of Omicron infections.

3 Aug 2022

Persistent viral infections within hosts cause post-acute sequelae of COVID-19, research shows

A research team, comprised of Associate Professor Tomonari Sumi of the Research Institute for Interdisciplinary Science at Okayama University and Associate Professor Kouji Harada of the Center for IT-based Education at Toyohashi University of Technology, has developed a mathematical model of the immune response within infected hosts that considers systemic infection of a novel coronavirus (SARS-CoV-2), and demonstrated by conducting experimental computer simulations that persistent viral infections within hosts potentially cause long COVID or post-acute sequelae of COVID-19.

3 Aug 2022

Case series of first 3 monkeypox patients in Massachusetts treated with tecoviromat

A team of US-based scientists has described the therapeutic efficacy of a pan-Orthopoxvirus inhibitor, tecovirimat, in patients with monkeypox infection

3 Aug 2022

Memory B and T cell responses to the SARS-CoV-2 spike protein before and after the third BNT162b2 booster

Researchers evaluated memory B and T cell responses to SARS-CoV-2 before and after the third dose of the BNT162b2 vaccine.

3 Aug 2022

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

3 Aug 2022

Music festivals embrace overdose reversal drugs, but fentanyl testing kits remain taboo

A 26-year-old was found dead at his campsite during the Bonnaroo Music and Arts Festival in 2019. The toxicology report linked his death to a grim trend that has only worsened since.

3 Aug 2022

Further SARS-CoV-2 variants, and intermittent epidemics may become the 'new normal'

A new study explores the dynamics of the SARS-CoV-2 Omicron and other variants circulating in England.

2 Aug 2022

Sustained low wages associated with accelerated memory decline later in life

Sustained low wages are associated with significantly faster memory decline, according to a new study by Columbia University Mailman School of Public Health.

2 Aug 2022

International travel restrictions were a key intervention for slowing COVID-19 spread, study shows

A study of COVID-19 variant transmission into and across Canada shows that international travel restrictions were a key intervention for reducing or slowing spread, according to a report published today in eLife.

2 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Human anti-desmoglein 2 levels are associated with COVID-19 severity

In a new study, researchers assessed the association between anti-desmoglein (DSG) 1, 2 and 3 auto-antibodies (auto-Abs) in acute and convalescent serum samples obtained from patients with COVID-19 of varying severity.

2 Aug 2022

Pre-existing anti-SARS-CoV-2 immunity decreases viral spread but increase SARS-CoV-2 Omicron competitiveness in hamsters

In a new study, researchers assessed the impact of pre-existing immunity against SARS-CoV-2 acquired by previous infections (PI) or COVID-19 vaccination on the transmission of SARS-CoV-2 variants of concern such as Delta and Omicron.

2 Aug 2022

immunity News and Research

Study identifies broad-spectrum antibody that neutralizes SARS-CoV-2 variants of concern

How does the flu vaccine affect the risk of contracting COVID-19?

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

Disease progression in the rhesus macaque model upon inoculation with the Delta, Omicron BA.1, and Omicron BA.2 variants

Was there a benefit of vaccinating health care workers with a fourth dose of BNT162b2 vaccine during the Omicron outbreak?

Epidemic model shows that intermediate levels of asymptomatic SARS-CoV-2 infection lead to the highest levels of epidemic fatalities

Study uses digital technology to evaluate antibody response following COVID-19 boosters

Hybrid immunity retained six months after SARS-CoV-2 exposure

Persistent viral infections within hosts cause post-acute sequelae of COVID-19, research shows

Case series of first 3 monkeypox patients in Massachusetts treated with tecoviromat

Memory B and T cell responses to the SARS-CoV-2 spike protein before and after the third BNT162b2 booster

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

Music festivals embrace overdose reversal drugs, but fentanyl testing kits remain taboo

Further SARS-CoV-2 variants, and intermittent epidemics may become the 'new normal'

Sustained low wages associated with accelerated memory decline later in life

International travel restrictions were a key intervention for slowing COVID-19 spread, study shows

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Human anti-desmoglein 2 levels are associated with COVID-19 severity

Pre-existing anti-SARS-CoV-2 immunity decreases viral spread but increase SARS-CoV-2 Omicron competitiveness in hamsters

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