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Combinational therapy with antibiotics and stem cells effectively treats bone infections

Bone infections caused by implants are difficult to treat and usually require a prolonged course of antibiotic treatment.

1 Oct 2020

Newly developed fusion protein could improve COVID-19 research

Researchers at the Paul Scherrer Institute in Switzerland have developed a high-quality recombinant virus protein that could be applied in the development of vaccines against the 2019 novel coronavirus (2019-nCoV) and in the detection of novel viruses or antibodies.

30 Sep 2020

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

A team of scientists at the University of Groningen, in the Netherlands, demonstrates that a natural plant product, resveratrol, and its structural analog, pterostilbene, have long-lasting antiviral effects against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv preprint server.

28 Sep 2020

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Now in new research published on the preprint server bioRxix*, a novel formulation of the drug Niclosamide (NIC) is observed to be effective against SARS-CoV-2 and MERS-CoV in mouse models; it also protects against methicillin-resistance Staphylococcus aureus pneumonia and inflammatory lung damage.

28 Sep 2020

Risk factors for mortality among hospitalized patients with COVID-19

A new study by scientists at biotechnology company Genentech, Inc., and published on the preprint server medRxiv in September 2020 attempts to identify the factors which may shape the risk for death in COVID-19 disease.

27 Sep 2020

New device helps study the reaction of individual cells to mechanical stress

The behavior of cells is controlled by their environment. Besides biological factors or chemical substances, physical forces such as pressure or tension are also involved.

25 Sep 2020

ZwickRoell’s zwickiLine Testing System Validated for Cleanroom Use

The importance of cleanrooms is currently in the spotlight as the global community awaits a vaccine for Covid-19.

25 Sep 2020

Human-to-cat transmission of SARS-CoV-2 confirmed

Cat-to-cat transmission of SARS-CoV-2 has been experimentally proven, but little is known about the significance of this novel virus as a feline pathogen or its reverse zoonotic potential. The establishment of new animal reservoirs of SARS-CoV-2 could pose serious problems for human health in the future.

24 Sep 2020

A possible inverse relationship between Dengue and COVID-19 in Brazil

Their study titled, “How super-spreader cities, highways, hospital bed availability, and dengue fever influenced the COVID-19 epidemic in Brazil,” was released pre-peer review on the preprint medRxiv* early this week.

24 Sep 2020

Validating COVD-19 testing systems for cleanroom use

The importance of cleanrooms is currently in the spotlight as the global community awaits a vaccine for Covid-19.

24 Sep 2020

NIST researchers develop 3D-printing technique to fabricate gels and soft materials

Researchers at the National Institute of Standards and Technology (NIST) have developed a new method of 3D-printing gels and other soft materials. Published in a new paper, it has the potential to create complex structures with nanometer-scale precision.

23 Sep 2020

Discovering a molecule that could interfere with SARS-CoV-2 replication

In this interview, News-Medical speaks to Stepan Nersisyan about his discovery of a molecule that could replicate SARS-CoV-2.

22 Sep 2020

SARS-CoV-2 infects monocytes and macrophages, without cytopathic effect

A team of researchers from Aix-Marseille Univ, IHU-Méditerranée Infection, Institut Paoli Calmettes and Laboratoire d’Immunologie, Marseille, France, conducted experiments to determine if SARS-CoV-2 can affect the myeloid compartment or infect monocytes and macrophages.

20 Sep 2020

Study examines performance of fabrics for home-made masks against the spread of COVID-19

Studies indicate that homemade masks help combat the spread of viruses like COVID-19 when combined with frequent hand-washing and physical distancing.

19 Sep 2020

Study invalidates Ebselen and other broad-spectrum SARS-CoV-2 Mpro inhibitors

Other novel compounds with Mpro inhibitory activity have also been claimed to have antiviral activity. These include ebselen, disulfiram, tideglusib, carmofur, shikonin, and PX-12. A new research paper discusses the role of these molecules as potential Mpro inhibitors in the prevention of SARS-CoV-2 infection.

18 Sep 2020

New drug candidate suppresses SARS-CoV-2 replication

Researchers at Stanford University and Utah State University have developed a novel inhibitor of the coronavirus main protease (Mpro) that effectively suppresses the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Researchers secure NIH funding to study differences in glioblastoma between males and females

A team led by researchers from Case Western Reserve University School of Medicine and Cleveland Clinic Lerner Research Institute has secured $10.4 million over five years from the National Institutes of Health/National Cancer Institute to explore at the molecular level the differences in glioblastoma between males and females.

17 Sep 2020

Smart drug delivery system may help treat spinal cord injuries, neurological disorders

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders.

17 Sep 2020

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use in treating pneumonia, binds to the receptors that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to in human cells.

17 Sep 2020

Blood viscometers could help guide the treatment of Covid-19 patients

One of the biggest challenges facing medical teams treating Covid-19 patients is identifying which ones are likely to suffer the most extreme responses to the virus.

17 Sep 2020