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Stabilized prefusion spike vaccine candidate induces powerful immune response

A new research paper by scientists at Janssen Vaccines & Prevention BV, in the Netherlands and published on the preprint server bioRxiv* is based on the assumption that an effective vaccine against these infections will induce neutralizing antibodies and an immune response favoring Th1 immunity.

3 Aug 2020

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) depends on its ability to infect new host cells following its replication and release from infected cells. This pivots on its ability to bind to cell surface receptors like the ACE2 enzyme.

3 Aug 2020

Severe fatigue common in COVID-19, independent of disease severity

Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often complain of fatigue, but now a new study shows that it also causes severe and frequent fatigue in those who recover after mild illness too.

2 Aug 2020

Researchers identify differences in clinical features of non-obese patients with NAFLD

Researchers from the University of Tsukuba identify differences in the clinical features of non-obese patients with non-alcoholic fatter liver disease based on their sex and body mass index.

2 Aug 2020

New bivalent vaccine delivers robust cell-mediated and humoral immunity against SARS-CoV-2

In a groundbreaking bioRxiv study, US researchers demonstrate the capability of next-generation bivalent human adenovirus serotype 5 (hAd5) vaccine for inducing both cellular and humoral immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – using both an S protein sequence optimized for cell surface expression and a conserved nucleocapsid antigen designed to be transported to the endosomal subcellular compartment.

2 Aug 2020

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

By exploiting the tools of synthetic biology, the researchers from Turkey have successfully developed a de novo riboregulator system for rapidly detecting the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic material. Their paper is currently available on medRxiv preprint server.

2 Aug 2020

Research suggests New York City may have reached coronavirus herd immunity threshold

A new study by researchers at University of Illinois at Urbana-Champaign and Brookhaven National Laboratory and published on the preprint server medRxiv in July 2020 discusses the effect of a factor called persistent contact heterogeneity on the final epidemic size of COVID-19.

31 Jul 2020

Study sheds light on potential new treatment approach in AML patients

Tyrosine kinases are protein enzymes that have many functions within cells, including cell signaling, growth, and division. Sometimes these enzymes can be overactive, which helps cancer cells survive and multiply.

31 Jul 2020

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Grants totaling nearly $3.5 million give early career investigators independence to pursue brave and bold cancer research.

31 Jul 2020

Harbour BioMed and Viva Biotech announce strategic collaboration to promote incubation of biotech startups

Harbour BioMed, a global clinical stage biopharmaceutical company and Viva Biotech (Shanghai) Ltd., a world-leading structure-based drug discovery platform today announced a strategic partnership under which both parties will collate their respective expertise in drug discovery and development to promote the incubation of innovative biotech startups.

31 Jul 2020

COVID-19 rapid antibody test receives CE mark and mass production begins

The COVID-19 rapid antibody test, developed by Abingdon Health, the medical device manufacturer leading the UK-Rapid Test Consortium, has received its CE mark. This means it is approved for professional use in the UK and EU.

31 Jul 2020

Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Scientists led by Javier Martinez from the Max Perutz Labs, a joint venture of the Medical University of Vienna and the University of Vienna, have identified a unique chemical reaction at the end of RNA molecules for the first time in human cells.

31 Jul 2020

Study offers new possibilities for developing anti-aging drugs

KAIST researchers have been able to dial up and down creatures' lifespans by altering the activity of proteins found in roundworm cells that tell them to convert sugar into energy when their cellular energy is running low.

31 Jul 2020

New simple way of detecting COVID-19 in blood plasma

Even as the COVID-19 pandemic claims increasing numbers of patients, testing numbers are rising in most nations at the leading edge. However, the current reverse transcriptase-polymerase chain reaction (RT PCR) testing is often unavailable and takes up to several days for results to arrive.

31 Jul 2020

War of sugars - estrogen provides protection in COVID-19

Now a new study published on the preprint server bioRxiv in July 2020 reports that sex hormones could affect the function of the fusion protein that is dependent upon the human ACE2 receptor, thus preventing the entry of the virus into the host cell.

31 Jul 2020

Researchers discover neural progenitor cells in the optic nerve

Researchers at the University of Maryland School of Medicine (UMSOM) have for the first time identified stem cells in the region of the optic nerve, which transmits signals from the eye to the brain.

30 Jul 2020

Researcher uses in silico analysis of SARS-CoV-2 spike protein to fast-track passive immunity

With millions of COVID-19 cases reported across the globe, people are turning to antibody tests to find out whether they have been exposed to the coronavirus that causes the disease. But what are antibodies? Why are they important? If we have them, are we immune to COVID-19? And if not, why not?

30 Jul 2020

Antioxidants in diet could raise risk of bowel cancer, new study reveals

Health benefits of antioxidants in food have been proven across a considerable body of scientific literature. Now, a new study shows that too much of a good thing may not be that good! Typically antioxidants in food, including polyphenols, flavonoids, and other plant compounds, could raise the risk of bowel cancer finds a new study from Israeli researchers.

30 Jul 2020

Scientists develop a blood test that can spot Alzheimer's disease early

Alzheimer's disease is an irreversible neurodegenerative disease, and there is still no way to treat it. Many cases of the condition are diagnosed when the disease has already progressed, making it difficult to manage. Now, researchers have developed a new test that can spot Alzheimer's disease early on.

30 Jul 2020

Immunosuppressive steroids help tumors to evade the immune system

A new study has revealed that tumors can evade the immune system by telling immune cells to produce immunosuppressive steroids.

30 Jul 2020

Protein C News and Research

Stabilized prefusion spike vaccine candidate induces powerful immune response

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

Severe fatigue common in COVID-19, independent of disease severity

Researchers identify differences in clinical features of non-obese patients with NAFLD

New bivalent vaccine delivers robust cell-mediated and humoral immunity against SARS-CoV-2

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

Research suggests New York City may have reached coronavirus herd immunity threshold

Study sheds light on potential new treatment approach in AML patients

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Harbour BioMed and Viva Biotech announce strategic collaboration to promote incubation of biotech startups

COVID-19 rapid antibody test receives CE mark and mass production begins

Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Study offers new possibilities for developing anti-aging drugs

New simple way of detecting COVID-19 in blood plasma

War of sugars - estrogen provides protection in COVID-19

Researchers discover neural progenitor cells in the optic nerve

Researcher uses in silico analysis of SARS-CoV-2 spike protein to fast-track passive immunity

Antioxidants in diet could raise risk of bowel cancer, new study reveals

Scientists develop a blood test that can spot Alzheimer's disease early

Immunosuppressive steroids help tumors to evade the immune system

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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