Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Colchicine may have therapeutic potential against COVID-19

A new study describes the results of colchicine in mitigating the inflammatory storm associated with COVID-19, and thus preventing a percentage of severe and critical cases.

1 Feb 2021

Food guidelines change but fail to take cultures into account

The U.S. Department of Agriculture and the Department of Health and Human Services have once again developed new food guidelines for Americans that urge people to customize a diet of nutrient-dense food. For the first time, they make recommendations for infant nutrition and for different stages of life.

1 Feb 2021

Enriched diet and companionship can reduce pain in mice with sickle cell disease

Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin.

1 Feb 2021

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Adding mushrooms to diet increases the intake of micronutrients

Researchers have identified another good reason to eat more mushrooms. New research , published in Food Science & Nutrition (January 2021) found that adding a mushroom serving to the diet increased the intake of several micronutrients, including shortfall nutrients such as vitamin D, without any increase in calories, sodium or fat.

1 Feb 2021

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

Now, a new preprint research paper describes a chimpanzee adenovirus-vectored vaccine that, when administered intranasally in rhesus macaques, led to a robust immune response and demonstrated protection against infection by the virus that causes COVID-19, namely, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The preprint is published on the bioRxiv server.

1 Feb 2021

E484K mutation is potentially associated with SARS-CoV-2 adaptive fitness

A team of Brazilian scientists has recently conducted genomic and phylogenetic analyses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome to understand the viral evolution process better. Their analyses reveal that the E484K mutated variant of SARS-CoV-2 is present in three different lineages in four Brazilian regions and that the mutation may serve as a common solution for viral evolution.

31 Jan 2021

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Researchers from Osaka University have described the link between accurate protein folding and misfolding that can lead to the formation of amyloid fibers, which are implicated in neurodegenerative diseases

31 Jan 2021

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19).

31 Jan 2021

Crystal structures of nanobodies could aid the design of COVID-19 therapies

Researchers at the National Institutes of Health in Bethesda, Maryland, have shown how certain synthetic nanobodies bind to the agent that causes coronavirus disease 2019 (COVID-19) – a development that could help inform the design of therapies.

31 Jan 2021

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that the independent Data Safety Monitoring Board (DSMB) for the global Phase 2/3 study of opaganib in patients with severe COVID-19, unanimously recommended to continue the study following a pre-scheduled futility review of unblinded efficacy data from the first 135 patients treated in the study and safety data from the first 175 patients.

30 Jan 2021

Researchers uncover the physics behind formation of branching microtubules during cell division

As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids.

30 Jan 2021

Study unravels relationship status of important receptor on immune and cancer cells

An important receptor on the surface of cancer and immune cells prefers to remain noncommittal; sometimes it is present as a single, sometimes as a pair. This was first shown by an MDC team in the journal PNAS, and will decisively advance the development of new medications.

30 Jan 2021

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 protein overproduction appears to trigger triple-negative breast cancer and possibly some other malignancies.

29 Jan 2021

Study shows BioNTech-Pfizer COVID-19 vaccine's ability to neutralize UK viral variant

In a study evaluating the BioNTech-Pfizer COVID-19 vaccine's ability to neutralize the B.1.1.7 ("UK") viral variant, researchers found no loss of immune protection compared to that against the original Wuhan reference strain.

29 Jan 2021

Study finds locations of early prion protein accumulation in the eye

The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes of Health scientists.

29 Jan 2021

Scientists study how different genes dance to the circadian rhythm

In 2017, the Nobel Prize in Physiology or Medicine went to three scientists who uncovered the molecular mechanisms that control the circadian rhythm, otherwise known as the "wake-sleep" cycle.

29 Jan 2021

Scientists unravel how lipids distribute proteins within cells

An international team of scientists, coordinated by the Seville Institute of Biomedicine and the University of Seville has solved one of the hitherto unresolved enigmas of basic biology: how exactly do lipids distribute proteins within a cell? To do this, they used a new, completely innovative microscopy technology, which they applied to "mutant" cells they designed in their laboratory.

29 Jan 2021

Study finds surprising defensive functions of the immune system against new viral attacks

Scientists are opening new windows into understanding more about the constantly shifting evolutionary arms race between viruses and the hosts they seek to infect.

29 Jan 2021

Protein News and Research

Further Reading

Colchicine may have therapeutic potential against COVID-19

Food guidelines change but fail to take cultures into account

Enriched diet and companionship can reduce pain in mice with sickle cell disease

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Adding mushrooms to diet increases the intake of micronutrients

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

E484K mutation is potentially associated with SARS-CoV-2 adaptive fitness

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Crystal structures of nanobodies could aid the design of COVID-19 therapies

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

Researchers uncover the physics behind formation of branching microtubules during cell division

Study unravels relationship status of important receptor on immune and cancer cells

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Study shows BioNTech-Pfizer COVID-19 vaccine's ability to neutralize UK viral variant

Study finds locations of early prion protein accumulation in the eye

Scientists study how different genes dance to the circadian rhythm

Scientists unravel how lipids distribute proteins within cells

Study finds surprising defensive functions of the immune system against new viral attacks

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