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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Taiho Pharmaceutical announces early stage data for eight novel oncology compounds

Taiho Pharmaceutical Co., Ltd., the developer of the first orally available fluorouracil (FU) Chemotherapeutic treatment (TS-1/S-1), is presenting early stage data for eight novel oncology compounds, including potential first-in-class therapies.

7 Nov 2012

UCLA study to uncover risk profiles of breast cancer survivors likely to suffer from depression

UCLA researchers received a five-year, $5 million grant from the National Cancer Institute that will fund a study seeking to uncover risk profiles of breast cancer survivors likely to suffer from depression.

7 Nov 2012

Researchers succeed in teaching computers how to identify commonalities in DNA sequences

Johns Hopkins researchers have succeeded in teaching computers how to identify commonalities in DNA sequences known to regulate gene activity, and to then use those commonalities to predict other regulatory regions throughout the genome. The tool is expected to help scientists better understand disease risk and cell development.

7 Nov 2012

Genetic testing valuable in determining etiology for childhood hearing loss

Genetic testing for a certain mutation in pediatric patients is valuable in determining a cause for unexplained hearing loss, according to a study in the November 2012 issue of Otolaryngology-Head and Neck Surgery.

6 Nov 2012

Chromosome 22q11.2 deletion syndrome anxiety linked to poorer adaptive behaviors

UC Davis researchers have found that for children with the genetic disorder known as chromosome 22q11.2 deletion syndrome anxiety -- but not intelligence -- is linked to poorer adaptive behaviors, such as self-care and communication skills, that affect daily life. The developmental syndrome, which is associated with a constellation of physical, cognitive and psychiatric problems, usually is apparent at birth or early childhood, and leads to lifelong challenges.

6 Nov 2012

Dysregulation of CISTR-ACT causes brachydactyly type E

The patients have single short fingers (metacarpals) and toes (metatarsals) and can be restricted in growth due to a shortened skeleton. This hereditary disease is called brachydactyly type E (Greek for short fingers).

6 Nov 2012

Endo, Bioniche decide to end second Urocidin Phase III trial on non-muscle-invasive bladder cancer

Bioniche Life Sciences Inc., a research-based, technology-driven Canadian biopharmaceutical company, today announced that a second Phase III clinical trial with Urocidin in non-muscle-invasive bladder cancer is being discontinued.

5 Nov 2012

Affymetrix reports net loss of $17.9 million for third quarter 2012

Affymetrix, Inc., today reported its operating results for the third quarter of 2012. Total revenue for the quarter was $79.6 million, including approximately $17.6 million in revenue from eBioscience during the third quarter of 2012. This compares to total revenue of $64.0 million for the same period of 2011.

5 Nov 2012

New insight on ability of certain PAH-derived lesions to evade DNA repair machinery

A person doesn't have to go far to find a polycyclic aromatic hydrocarbon (PAH). These carcinogen precursors are inhaled through automobiles exhaust during the morning commute, are present in a drag of cigarette smoke, and are part of any barbequed meal.

4 Nov 2012

Caltech-led team discovers enzyme responsible for neural crest cell development

During the early developmental stages of vertebrates-animals that have a backbone and spinal column, including humans-cells undergo extensive rearrangements, and some cells migrate over large distances to populate particular areas and assume novel roles as differentiated cell types.

3 Nov 2012

New partnership to make advancements in personalized breast cancer treatment and care

The Edith Sanford Breast Cancer Foundation and The Scripps Research Institute today announced the formation of a dynamic partnership that will lay the groundwork for lifesaving advancements in personalized breast cancer treatment and care.

3 Nov 2012

Scientists sequence and analyze human genomes to discover many variants

Thanks to powerful computational tools developed at Simon Fraser University, more than 100 scientists from around the world have genetically mapped the largest and most varied number of human genomes to date.

3 Nov 2012

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance."

3 Nov 2012

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

In one of the largest studies of its kind ever conducted, an international team of scientists has thrown new light on the genetic basis of the inflammatory bowel diseases (IBD).

3 Nov 2012

XJB-5-131 compound suppresses symptoms of Huntington's in mice

There's new hope in the fight against Huntington's disease. A group of researchers that includes scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.

2 Nov 2012

Study describes role of TFIIB protein in helping cells repair DNA damage

In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors.

2 Nov 2012

CSHL scientists discover new way to specifically target and kill cancer cells

Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. To do this they need to speed up their metabolism.

1 Nov 2012

University of Sheffield scientists reveal secrets of DNA repair

Scientists from the University of Sheffield have unlocked one of the secrets to DNA repair -helping doctors identify DNA base damage and a patient's susceptibility to certain types of cancer.

1 Nov 2012

Microbiologists confirm existence of new tick disease in Switzerland

Until now, we knew that ticks primarily transmit two pathogens to humans in Switzerland: the bacterium Borrelia burgdorferi - which causes borreliosis - and the early-summer-meningoencephalitis virus, which can cause cerebral inflammation. Now, microbiologists from the University of Zurich confirm the existence of another tick disease in Switzerland - neoehrlichiosis.

1 Nov 2012

Benaroya Research Institute at Virginia Mason wins Grand Challenges Explorations grant

Benaroya Research Institute at Virginia Mason (BRI) announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

1 Nov 2012

DNA News and Research

Further Reading

Taiho Pharmaceutical announces early stage data for eight novel oncology compounds

UCLA study to uncover risk profiles of breast cancer survivors likely to suffer from depression

Researchers succeed in teaching computers how to identify commonalities in DNA sequences

Genetic testing valuable in determining etiology for childhood hearing loss

Chromosome 22q11.2 deletion syndrome anxiety linked to poorer adaptive behaviors

Dysregulation of CISTR-ACT causes brachydactyly type E

Endo, Bioniche decide to end second Urocidin Phase III trial on non-muscle-invasive bladder cancer

Affymetrix reports net loss of $17.9 million for third quarter 2012

New insight on ability of certain PAH-derived lesions to evade DNA repair machinery

Caltech-led team discovers enzyme responsible for neural crest cell development

New partnership to make advancements in personalized breast cancer treatment and care

Scientists sequence and analyze human genomes to discover many variants

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

XJB-5-131 compound suppresses symptoms of Huntington's in mice

Study describes role of TFIIB protein in helping cells repair DNA damage

CSHL scientists discover new way to specifically target and kill cancer cells

University of Sheffield scientists reveal secrets of DNA repair

Microbiologists confirm existence of new tick disease in Switzerland

Benaroya Research Institute at Virginia Mason wins Grand Challenges Explorations grant

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