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Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Case study: Cannabinoid hyperemesis syndrome in a patient with ALS

This case study of a patient with ALS and symptoms of cannabinoid hyperemesis syndrome emphasizes the need for research into the use of medicinal cannabis.

12 Jun 2019

New method produces opiate antidotes using microorganism found in opium poppy waste

Overdose from opiates has skyrocketed. According to the National Center for Health Statistics, on average, 130 Americans die every day from an opioid overdose.

12 Jun 2019

Electronic consultations in allergy and immunology may reduce need for specialist visits

A study from Massachusetts General Hospital researchers finds that electronic consultations in allergy and immunology can simplify the process of providing the most appropriate care, often reducing the need for in-person specialist visits.

12 Jun 2019

Study: Government policy interventions to fight antimicrobial resistance have not been rigorously evaluated

Governments have a wide variety of policy options at their disposal to respond to the growing threat of antimicrobial resistance, but many of these approaches have not been rigorously evaluated, according to a new study published this week in PLOS Medicine by Susan Rogers Van Katwyk of the University of Ottawa, Canada, and colleagues.

From PLOS ONE 12 Jun 2019

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

Colorectal cancer is the second leading cause of cancer death in the U.S., expected to cause about 51,000 deaths in 2019. But until now, it was unclear which drugs were most effective for which patients.

12 Jun 2019

Chemists build rich collection of natural product-like macrocycles for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class.

12 Jun 2019

Fibrinogen a key player in health and disease, says new study

A new study from the University of Alberta demonstrated that the blood clotting protein called fibrinogen also regulates MMP-2, an enzyme involved in immunity and in clot formation inside blood vessels. Prolonged MMP-2 inhibition could potentially produce a deficiency state with severe consequences.

12 Jun 2019

Malaria drug may help those with hereditary hearing loss finds study

Researchers have found that anti-malarial drug artemisinin could help patients with genetic or hereditary hearing loss. The study results were published in the latest issue of the journal Proceedings of the National Academy of Sciences (PNAS). The study was titled, “Unconventional secretory pathway activation restores hair cell mechanotransduction in an USH3A model.”

12 Jun 2019

Smart phone plus nanoscale porous silicon equals simple home medical tests

The simplest home medical tests might look like a deck of various silicon chips coated in special film, one that could detect drugs in the blood, another for proteins in the urine indicating infection, another for bacteria in water and the like

11 Jun 2019

Study finds potential treatment for patients with Complex Regional Pain Syndrome

A study, published today in PNAS, has found a potential treatment for patients with Complex Regional Pain Syndrome.

11 Jun 2019

FDA overlooked red flags in drugmaker’s testing of new depression medicine

Ketamine is a darling of combat medics and clubgoers, an anesthetic that can quiet your pain without suppressing breathing and a hallucinogenic that can get you high with little risk of a fatal overdose.

11 Jun 2019

Patients receiving drug therapy before LVAD implantation have high risk of right-sided heart failure

Patients with left-sided heart failure who get implanted devices to improve the pumping of their hearts may be more likely to develop heart failure on the opposite side of their hearts if they are pre-treated with off-label selective vasodilator drugs, according to new research published in Circulation: Heart Failure, an American Heart Association journal.

11 Jun 2019

Researchers succeed in conquering chronic infection with hepatitis B virus

Researchers at Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with researchers at the University Medical Center Hamburg-Eppendorf and the University Hospital Heidelberg, have for the first time succeeded in conquering a chronic infection with the hepatitis B virus in a mouse model.

11 Jun 2019

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

"Green revolution" in the early 1950s, the extensive cultivation of Dwarf Rice solves the food problem in developing countries. At present, chronic infection with hepatitis B virus (HBV) has been a major public health problem.

11 Jun 2019

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

The scientific research team from the Universidad Pablo de Olavide led by doctor José Antonio Sánchez Alcázar has published a new study in the international magazines Molecular Neorubiology and Neural Regeneration Research.

11 Jun 2019

Scorpion venom contains compounds that could help fight Staph and tuberculosis bacteria

Researchers at Stanford University and Universidad Nacional Autónoma de México (UNAM) have found that a scorpion found in Eastern Mexico has a venom that could have antibacterial properties.

10 Jun 2019

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Today, the U.S. Food and Drug Administration granted accelerated approval to Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy bendamustine and a rituximab product (a combination known as "BR"), to treat adult patients with diffuse large B-cell lymphoma (DLBCL) that has progressed or returned after at least two prior therapies.

10 Jun 2019

Drugs News and Research

Scientists discover weakness in common cold virus

Case study: Cannabinoid hyperemesis syndrome in a patient with ALS

New method produces opiate antidotes using microorganism found in opium poppy waste

Electronic consultations in allergy and immunology may reduce need for specialist visits

Study: Government policy interventions to fight antimicrobial resistance have not been rigorously evaluated

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

Chemists build rich collection of natural product-like macrocycles for drug discovery

Fibrinogen a key player in health and disease, says new study

Malaria drug may help those with hereditary hearing loss finds study

Smart phone plus nanoscale porous silicon equals simple home medical tests

Study finds potential treatment for patients with Complex Regional Pain Syndrome

FDA overlooked red flags in drugmaker’s testing of new depression medicine

Patients receiving drug therapy before LVAD implantation have high risk of right-sided heart failure

Researchers succeed in conquering chronic infection with hepatitis B virus

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Study suggests therapeutic solutions for pantothenate kinase-associated neurodegeneration

Scorpion venom contains compounds that could help fight Staph and tuberculosis bacteria

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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