Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Research shows that rates of coronary heart disease are higher with longer duration of obesity

In a study of adults recruited and followed up over the past 3 decades in the United States, longer duration of overall and abdominal obesity beginning in young adulthood was associated with higher rates of coronary artery calcification, a subclinical predictor of coronary heart disease, according to a study in the July 17 issue of JAMA.

17 Jul 2013

People with cheerful temperaments are less likely to suffer cardiac diseases

People with cheerful temperaments are significantly less likely to suffer a coronary event such as a heart attack or sudden cardiac death, new Johns Hopkins research suggests.

12 Jul 2013

Zinc exhibits ideal physiological corrosion behavior for bioabsorbable stents

In 2012, more than 3 million people had stents inserted in their coronary arteries. These tiny mesh tubes prop open blood vessels healing from procedures like a balloon angioplasty, which widens arteries blocked by clots or plaque deposits.

12 Jul 2013

Researchers are one step closer to finding solution for atherosclerosis in diabetic patients

Researchers at Joslin Diabetes Center have discovered that when excessive PKC beta is found in the endothelium, the thin layer of cells that line blood vessels, atherosclerosis is exacerbated. Their findings were published on-line on June 11 by Circulation Research.

11 Jul 2013

Cheerful people are less likely to suffer heart attack

Johns Hopkins researchers link positive outlook to reduction in cardiac events such as heart attacks. People with cheerful temperaments are significantly less likely to suffer a coronary event such as a heart attack or sudden cardiac death, new Johns Hopkins research suggests.

10 Jul 2013

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

Low vitamin D blood levels are linked to greater risk of heart disease in whites and Chinese, but not in blacks and Hispanics, according to a study appearing this week in JAMA, a journal published by the American Medical Association.

10 Jul 2013

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, announced today the publication of pre-clinical data for VB-201 in the journal of Atherosclerosis.

8 Jul 2013

Activation of brown fat increases heart-related mortality during winter

More people die from heart-disease during the winter months, and according to a new study published in the journal Cell Metabolism, the increase in mortality is possibly due to the accelerated growth of atherosclerotic plaque in the blood vessels caused by the activation of brown fat by the cold.

3 Jul 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

The Fondation Leducq in Paris, France, dedicated to improving human health through international efforts to combat cardiovascular disease, awarded a $6 million grant award to a new global research network of cardiovascular scientists which includes three researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

2 Jul 2013

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes. The results, published today in Nature Immunology, suggest a common biochemical thread to multiple diseases and point the way to a new class of therapies that could treat chronic inflammation in these non-infectious diseases without crippling the immune system.

2 Jul 2013

DNA fragments in blood may help doctors to quickly identify coronary artery disease

DNA fragments in your blood may someday help doctors quickly learn if chest pain means you have narrowed heart arteries, according to a new study published in the American Heart Association journal Arteriosclerosis, Thrombosis, and Vascular Biology.

2 Jul 2013

Mount Sinai cardiologist receives AHA/ASA Ron Haddock International Impact Award

The American Heart Association (AHA) has awarded world-renowned cardiologist Dr. Valentin Fuster, MD, PhD, Director of Mount Sinai Heart at The Mount Sinai Medical Center, its prominent American Heart Association/American Stroke Association Ron Haddock International Impact Award.

28 Jun 2013

AtheroNova starts AHRO-001 Phase 1 clinical trial for treatment of atherosclerosis

AtheroNova Inc., a biotech company focused on the research and development of compounds to safely regress atherosclerotic plaque and improve lipid profiles in humans, today announces achievement of a major milestone with the initiation of a Phase 1 clinical trial with its lead compound, AHRO-001. The Phase 1 study will evaluate the safety, tolerability and pharmacokinetics of AHRO-001 in healthy volunteers.

25 Jun 2013

Researchers find RNA molecule that interferes with lipoprotein production, reduces hyperlipidemia

Hyperlipidemia, a condition with high levels of fats circulating in the bloodstream, is a known risk factor for various cardiovascular and metabolic disorders. While the Western diet often contributes to high levels of lipids such as cholesterol and triglycerides, over-production of the body's own lipoproteins can lead to hyperlipidemia, independent of food intake.

25 Jun 2013

Trees are effective tool in reducing air pollution and creating healthier urban environments

In the first effort to estimate the overall impact of a city's urban forest on concentrations of fine particulate pollution (particulate matter less than 2.5 microns, or PM2.5), a U.S. Forest Service and Davey Institute study found that urban trees and forests are saving an average of one life every year per city. In New York City, trees save an average of eight lives every year.

20 Jun 2013

MRI screening of aortic atherosclerosis can predict risk of heart attacks and other CVDs

Magnetic resonance imaging (MRI) of aortic atherosclerosis can predict the risk of heart attacks and other cardiovascular events in otherwise healthy individuals, researchers at UT Southwestern Medical Center have found.

19 Jun 2013

Men with haplogroup I of Y chromosome have 50% greater risk of developing heart disease

University of Leicester scientists have discovered a potential genetic contributor to the increased risk of heart disease among men.

18 Jun 2013

Two MRI measurements of abdominal aorta associated with future cardiovascular events

In a study of more than 2,000 adults, researchers found that two MRI measurements of the abdominal aorta - the amount of plaque in the vessel and the thickness of its wall - are associated with future cardiovascular events, such as a heart attack or stroke. Results of the study are published online in the journal Radiology.

18 Jun 2013

Athera receives support from FP7 for development of fully human antibody PC-mAb

Athera Biotechnologies AB today announced that future development costs of its fully human antibody PC-mAb up until proof-of-concept will be co-funded by the European Union's Seventh Framework Programme for Research (FP7) through a collaborative research grant. Karolinska Development AB owns 65% of Athera Biotechnologies AB.

17 Jun 2013

Acrolein offers potential tool to reduce symptoms of spinal cord injuries and multiple sclerosis

A medical test previously developed to measure a toxin found in tobacco smokers has been adapted to measure the same toxin in people suffering from spinal cord injuries and multiple sclerosis, offering a potential tool to reduce symptoms.

14 Jun 2013

Atherosclerosis News and Research

Further Reading

Research shows that rates of coronary heart disease are higher with longer duration of obesity

People with cheerful temperaments are less likely to suffer cardiac diseases

Zinc exhibits ideal physiological corrosion behavior for bioabsorbable stents

Researchers are one step closer to finding solution for atherosclerosis in diabetic patients

Cheerful people are less likely to suffer heart attack

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

Activation of brown fat increases heart-related mortality during winter

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

DNA fragments in blood may help doctors to quickly identify coronary artery disease

Mount Sinai cardiologist receives AHA/ASA Ron Haddock International Impact Award

AtheroNova starts AHRO-001 Phase 1 clinical trial for treatment of atherosclerosis

Researchers find RNA molecule that interferes with lipoprotein production, reduces hyperlipidemia

Trees are effective tool in reducing air pollution and creating healthier urban environments

MRI screening of aortic atherosclerosis can predict risk of heart attacks and other CVDs

Men with haplogroup I of Y chromosome have 50% greater risk of developing heart disease

Two MRI measurements of abdominal aorta associated with future cardiovascular events

Athera receives support from FP7 for development of fully human antibody PC-mAb

Acrolein offers potential tool to reduce symptoms of spinal cord injuries and multiple sclerosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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