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'Senolytic' therapy blunts liver tumor progression in animal models

"Senotherapy," a treatment that uses small molecule drugs to target "senescent" cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, Ph.D., a professor of Cell and Developmental Biology in the Perelman School of Medicine at the University of Pennsylvania and scientific director of the Abramson Family Cancer Research Institute.

20 May 2020

Study: Bioelectrical view can provide biological understanding of cellular processes

We use cells to breathe, to moderate body temperature, to grow and many other every day processes, however the cells in these processes are so complex its left scientists perplexed into how they develop in different environments.

20 May 2020

Smoking increases ACE2 protein in the lungs which may promote COVID-19 infection

Previous data from COVID-19 patients suggests that cigarette smokers are more likely to have health complications.

18 May 2020

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

A research group from Harvard Medical School reported two cryo-electron microscopy structures derived from a single preparation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in their paper available on the preprint server bioRxiv. Understanding the nuances of prefusion and postfusion conformations shed light on viral cell entry and may, in turn, guide the development of vaccines and drugs.

18 May 2020

Cancer biologists identify important drivers of tumor resistance

Cancer biologists at the Mays Cancer Center, home to UT Health San Antonio MD Anderson, have identified important drivers that enable tumors to change their behavior and evade anticancer therapies.

18 May 2020

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Boehringer Ingelheim today announced the acquisition of Northern Biologics Inc., a wholly owned subsidiary of Northern LP. By acquiring this entity, which focuses on therapeutic antibodies targeting the tumor microenvironment, Boehringer Ingelheim is now positioned at the forefront of the stromal biology space - an emerging area in cancer immunology.

From Boehringer Ingelheim International GmbH 18 May 2020

New study sheds light on the cause of stem cell mutations

Research from the University of Sheffield has given new insight into the cause of mutations in pluripotent stem cells and potential ways of stopping these mutations from occurring.

15 May 2020

New treatment discovered to reduce swelling after brain and spinal cord injuries

Scientists have discovered a new treatment to dramatically reduce swelling after brain and spinal cord injuries, offering hope to 75 million victims worldwide each year.

15 May 2020

A deep look into hormone-producing cells of the gut

Researchers from the Hubrecht Institute and Utrecht University generated an in-depth description of the human hormone-producing cells of the gut, in a large collaborative effort with other research teams. The results are presented in the scientific journal Cell on the 13th of May.

13 May 2020

Neovii and Tel Aviv University partner to develop novel COVID-19 vaccine

Ramot, Tel Aviv University's technology transfer company, and Neovii, a Swiss-based biopharmaceutical company and a member of Israel-based Neopharm Group, announced today that they have signed a research and license agreement to develop a novel and potentially life-saving COVID-19 vaccine.

12 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

UCLA researchers develop first roadmap of how human skeletal muscle develops

An interdisciplinary team of researchers at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA has developed a first-of-its-kind roadmap of how human skeletal muscle develops, including the formation of muscle stem cells.

11 May 2020

Indiana researchers identify new target for colorectal cancer immunotherapy

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a target for colorectal cancer immunotherapy.

11 May 2020

Link found between blood vessel inflammation and abnormalities in mitochondrial fission

The vast majority of cells in the human body contain tiny power plants known as mitochondria that generate much of the energy cells use for day-to-day activities.

11 May 2020

RNA interference machinery influences epithelial cell biology

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts.

9 May 2020

Scientists create German COVID-19 OMICS Initiative to accelerate research

How does the new coronavirus (SARS-CoV-2) change its genetic information? What other infections occur in patients with COVID-19? Are there genetic risk factors that favor an infection? Numerous genome researchers are pooling their expertise and sequencing infrastructure to make a scientific contribution to manage the COVID-19 pandemic.

9 May 2020

Researchers discover molecular mechanism that helps HSV1 infect the brain

Herpes simplex virus (HSV1) infections are initiated at mucosal surfaces where the virus infects epithelial cells.

8 May 2020

The Role of Microphysiological Systems for Oncology and Stem Cell Research

In this interview, Dr. Nancy Allbritton from The Allbritton Lab talks to News-Medical and Life Sciences about the revolutionary technology and techniques for the application of new technologies for oncology and stem cell research.

From Pittcon 6 May 2020

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases.

6 May 2020

Study provides evidence for safety and efficacy of chloroquine in COVID-19

After a pilot study (Huang et al.Journal of Molecular Cell Biology, in press), having proved the safety and effectiveness of the drug to reduce the viral RNA to undetectable levels in 10 COVID-19 patients, the researchers began this current study, published on the preprint server medRxiv.

5 May 2020

Cell Biology News and Research

'Senolytic' therapy blunts liver tumor progression in animal models

Study: Bioelectrical view can provide biological understanding of cellular processes

Smoking increases ACE2 protein in the lungs which may promote COVID-19 infection

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

Cancer biologists identify important drivers of tumor resistance

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

New study sheds light on the cause of stem cell mutations

New treatment discovered to reduce swelling after brain and spinal cord injuries

A deep look into hormone-producing cells of the gut

Neovii and Tel Aviv University partner to develop novel COVID-19 vaccine

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

UCLA researchers develop first roadmap of how human skeletal muscle develops

Indiana researchers identify new target for colorectal cancer immunotherapy

Link found between blood vessel inflammation and abnormalities in mitochondrial fission

RNA interference machinery influences epithelial cell biology

Scientists create German COVID-19 OMICS Initiative to accelerate research

Researchers discover molecular mechanism that helps HSV1 infect the brain

The Role of Microphysiological Systems for Oncology and Stem Cell Research

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

Study provides evidence for safety and efficacy of chloroquine in COVID-19

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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