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Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Cardamonin - a natural compound found in the spice cardamom and other plants - could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells.

3 Apr 2022

Investigational drug vupanorsen reduces non-HDL cholesterol by up to 28%

Investigational drug vupanorsen reduces non-HDL cholesterol by up to 28%

The investigational drug vupanorsen reduced total levels of non-high-density lipoprotein (non-HDL) cholesterol by up to 28% in patients with high cholesterol who were already taking a cholesterol-lowering statin medication, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Dr. Annette Rinck appointed as President of Leica Microsystems

Dr. Annette Rinck appointed as President of Leica Microsystems

Leica Microsystems, a leading manufacturer of microscopes and scientific instruments, has announced the appointment of Dr. Annette Rinck as its President, with effect from 1 April 2022.

From Leica Microsystems GmbH 1 Apr 2022

Study reveals how zinc supports immunity, suggests ways it could be used to improve health

Study reveals how zinc supports immunity, suggests ways it could be used to improve health

Zinc's immune-boosting properties are well-established, but scientists haven't known exactly how it works.

1 Apr 2022

Soy molasses and kudzu roots may help fight against pediatric tumors

Soy molasses and kudzu roots may help fight against pediatric tumors

Soy molasses and kudzu roots contain isoflavonoids with high antioxidant and cytotoxic activity, scientists have discovered.

30 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

A new study assessed the molecular dynamics of potentially active natural phytochemicals to target the SARS-CoV-2 main protease.

29 Mar 2022

Algal metabolites as novel drugs against viruses

Algal metabolites as novel drugs against viruses

A new review article published in the Journal of Biotechnology has provided information on various nutraceutical metabolites extracted from algae.

29 Mar 2022

Strand displacement mechanism in RNA appears to switch genetic expression from “on” to “off”

Strand displacement mechanism in RNA appears to switch genetic expression from “on” to “off”

Similar to a light switch, RNA switches (called riboswitches) determine which genes turn "on" and "off." Although this may seem like a simple process, the inner workings of these switches have confounded biologists for decades.

29 Mar 2022

New compound delivered in a nasal spray effectively treats delta variant infection in mice

New compound delivered in a nasal spray effectively treats delta variant infection in mice

Researchers have shown a new compound delivered in a nasal spray is highly effective in preventing and treating COVID-19 caused by the Delta variant in mice.

29 Mar 2022

Researchers show how an important inhibitor binds to the A2A receptor

Researchers show how an important inhibitor binds to the A2A receptor

The A2A receptor regulates how vigorously the innate immune system attacks diseased cells.

25 Mar 2022

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

A new study has focussed on screening and identification of possible SMIs of this PPI for COVID-19.

25 Mar 2022

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

A new study evaluated the N terminal domain of the SARS-CoV-2 nucleocapsid protein. It presented the targeted characteristics for selective ribonucleic acid identification by SARS-CoV-2 N in its 5'-genomic end.

24 Mar 2022

Non-hormonal male contraceptive effectively prevents pregnancy in mice

Non-hormonal male contraceptive effectively prevents pregnancy in mice

Women have many choices for birth control, ranging from pills to patches to intrauterine devices, and partly as a result, they bear most of the burden of preventing pregnancy.

24 Mar 2022

Deep-water cone snails produce a potentially painkilling compound, study reports

Deep-water cone snails produce a potentially painkilling compound, study reports

Scientists already know that the venom of cone snails, which prowl the ocean floor for a fish dinner, contains compounds that can be adapted as pharmaceuticals to treat chronic pain, diabetes and other human maladies.

24 Mar 2022

Oral version of remdesivir could extend its reach and benefits to COVID-19 patients

Oral version of remdesivir could extend its reach and benefits to COVID-19 patients

Scientists at the University of North Carolina at Chapel Hill are testing a new route for remdesivir, a pill form of the COVID-19 treatment that’s given to half of all hospitalized patients with the disease.

22 Mar 2022

Researchers discover a compound that reduces epileptic seizures

Researchers discover a compound that reduces epileptic seizures

Researchers studying epileptic seizures of the temporal lobe – the most common type of epilepsy – discovered a compound that reduces seizures in the hippocampus, a brain region where many such seizures originate.

22 Mar 2022

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions.

22 Mar 2022

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

A research team at Colorado State University has discovered that drugs used to treat malaria are also effective at treating a pulmonary disease similar to tuberculosis.

21 Mar 2022

Children with complex medical conditions often need out-of-network care, study finds

Children with complex medical conditions often need out-of-network care, study finds

Children with complex medical conditions, especially those who require behavioral health treatment, often have to go outside of their insurance plans' provider networks for care, a new study has found.

21 Mar 2022

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