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Retrospective analysis shows mortality rates and risk factors after prosthetic heart valve surgeries

Mechanical valve replacement is a primary treatment for rheumatic heart disease, yet prosthesis-related adverse outcomes remain underreported in India.

25 Nov 2025

White matter alterations connect coronary artery disease to cognitive decline

Individuals with coronary artery disease (CAD) - a constricting or blocking of blood vessels feeding the heart - face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive function is not fully understood.

25 Nov 2025

Genetic signals reveal why erectile dysfunction develops and who is most at risk

This multi-ancestry genomic study identifies key genetic loci underlying erectile dysfunction and shows that ED risk is shaped by both cardiometabolic and substance use–related genetic pathways. Using EHR-linked data, the researchers uncover SIM1-related mechanisms, modest PRS performance, and bidirectional genetic links with obesity, diabetes, and addiction traits.

25 Nov 2025

Extreme heat waves pose death risk for veterans with cardiometabolic conditions

Veterans living in California who have cardiometabolic conditions such as diabetes and high blood pressure experience significantly higher risk of dying during heat waves compared to cooler days, UCLA-led research finds.

25 Nov 2025

Deep learning AI model identifies first-of-its-kind biomarker of chronic stress

Using a deep learning AI model, researchers identified the first-of-its-kind biomarker of chronic stress detectable through routine imaging, according to research being presented next week at the annual meeting of the Radiological Society of North America.

25 Nov 2025

New platform enables unbiased evaluation of AI algorithms for diabetic eye screening

Researchers have developed the world's first real-world head-to-head testing platform to determine whether commercial artificial intelligence (AI) algorithms are fit for NHS use to detect disease in a fair, equitable, transparent and trustworthy way, using diabetic eye disease as the first example.

24 Nov 2025

Genetic factors behind impulsive choices tied to metabolic and mental health

Researchers from University of California San Diego have identified 11 genetic regions linked to delay discounting - the tendency to prefer smaller, immediate rewards over larger, delayed ones - shedding new light on how impulsive decision-making relates to both mental and physical health.

24 Nov 2025

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

24 Nov 2025

Elevated levels of five blood proteins can help predict mortality risk

Elevated levels of five proteins in our blood can help predict risk of mortality, a new study from the University of Surrey finds.

24 Nov 2025

Higher teen blood pressure predicts who develops heart disease

A study reveals that adolescent blood pressure levels are strong predictors of coronary atherosclerosis, emphasizing the importance of monitoring in youth.

24 Nov 2025

Hearing loss emerges as a key early warning sign for Alzheimer disease

Hearing loss also predicts a significantly higher risk of dementia, especially in APOE ε4 carriers, highlighting its value as an early risk marker.

23 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

New research identifies molecular pathways linking hot weather and preterm birth risk

An Emory University study, published Friday by Science Advances, provides the first evidence that exposure to higher temperatures during pregnancy is linked to specific biological changes in mothers that are also associated with preterm birth.

22 Nov 2025

American Heart Association honors schools and students for fighting childhood obesity

One in every five American children and teens is obese; that's up 35% from 2000, as severe childhood obesity rates have nearly doubled in that time.

22 Nov 2025

New signaling molecule drives development of tissue resident memory T cells

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

22 Nov 2025

Study highlights limitations of current cardiac screening tools

Current cardiac screening tools used to prevent heart attacks fail to identify nearly half of the people who are actually at risk of having one, according to a new study led by Mount Sinai researchers.

22 Nov 2025

Promising long-term vaccine for Crimean-Congo hemorrhagic fever developed

Crimean-Congo hemorrhagic fever (CCHF) is one of the world's most dangerous yet overlooked infectious diseases.

22 Nov 2025

New method can stop or reverse the decline of cellular energy production

Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production - a finding that could have revolutionary effects across medicine.

22 Nov 2025

Scientists identify cellular control points to tackle multiple viruses

Scientists were pleased when they learned more about how the common cold gains a foothold in the body, identifying key cellular checkpoints that are important targets of the virus.

21 Nov 2025

Combined healthy eating and exercise linked to greater reductions in visceral fat

Improving diet and increasing physical activity levels together may be more effective at preventing weight gain – particularly harmful fat inside the abdomen – than just changing one of these behaviours, new research from the University of Cambridge suggests.

21 Nov 2025