RNA News and Research

RSS

Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

ARPP21 gene mutation could be the cause of ALS

Researchers from the Neuromuscular Diseases Group and the Dementia Neurobiology Group of the Sant Pau Research Institute (IR Sant Pau) and the Memory Unit of the Sant Pau Hospital, led by neurologist Dr. Ricard Rojas-García, have identified a new mutation in the ARPP21 gene that could be the cause of Amyotrophic Lateral Sclerosis (ALS), a devastating neurodegenerative disease.

11 Jul 2024

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.

11 Jul 2024

Researchers identify molecular processes crucial for the maturation of Group 2 innate lymphoid cells

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Archaeal, fungal, viral, as well as bacterial, functional makers for autism spectrum disorder in children

Researchers investigated the associations between multikingdom gut microbiome components and functional markers with autism spectrum disorder through metagenomic sequencing of children's fecal samples.

11 Jul 2024

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Researchers elucidated the shared immune tolerance mechanisms in cancer and pregnancy, focusing on the role of an immune checkpoint protein as an onco-fetal immune tolerance checkpoint.

11 Jul 2024

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

10 Jul 2024

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network.

10 Jul 2024

Antonin (Tony) de Fougerolles appointed as new Chair of etherna

etherna, a leading mRNA technologies company, today announced the appointment of Antonin (Tony) de Fougerolles as Chair. Tony has served as an Independent Board Member since January 2023.

From etherna 10 Jul 2024

Exploring the benefits of miniaturizing NGS library preparation

In this interview, Huw Rees, a field application scientist at SPT Labtech, discusses the benefits of miniaturization in NGS library preparation and how using mosquito® can give you more value for your money.

From SPT Labtech 10 Jul 2024

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

Researchers performed saturation genome editing of the BAP1, whose dysfunction is related to cancer and impaired neurodevelopment.

10 Jul 2024

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Researchers trace the 60-year evolution of lipid nanoparticles (LNPs) for nucleic acid delivery, highlighting their potential to revolutionize gene therapy with safer and more effective treatments.

10 Jul 2024

COVID-19 and metallic taste: Study connects immunoglobulin levels to sensory impairment

Researchers investigated whether COVID-19-related sensory deficiencies are associated with transcriptome changes in the foliate papillae area of the tongue.

9 Jul 2024

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Researchers reveal both direct and indirect mechanisms of SARS-CoV-2-induced lymphopenia, highlighting the role of CD147 and alternative viral entry routes into T cells.

8 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Why do aortic aneurysms form in specific locations?

The sites where vascular aneurysms typically form have a predilection from the outset, even in healthy people. This is shown by a study conducted by medical researchers from Bochum and Bonn.

5 Jul 2024

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

The impact of heparan-sulfate-modified proteoglycans (HSPGs) on Alzheimer's disease-associated pathways.

5 Jul 2024

Researchers discover rare types of helper T cells associated with immune disorders

Researchers led by Yasuhiro Murakawa at the RIKEN Center for Integrative Medical Sciences (IMS) and Kyoto University in Japan and IFOM ETS in Italy have discovered several rare types of helper T cells that are associated with immune disorders such as multiple sclerosis, rheumatoid arthritis, and even asthma.

4 Jul 2024

RNA News and Research

Further Reading

ARPP21 gene mutation could be the cause of ALS

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Researchers identify molecular processes crucial for the maturation of Group 2 innate lymphoid cells

Archaeal, fungal, viral, as well as bacterial, functional makers for autism spectrum disorder in children

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Antonin (Tony) de Fougerolles appointed as new Chair of etherna

Exploring the benefits of miniaturizing NGS library preparation

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

60 years in the making: Nanoparticles revolutionize nucleotide delivery

COVID-19 and metallic taste: Study connects immunoglobulin levels to sensory impairment

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Why do aortic aneurysms form in specific locations?

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

Researchers discover rare types of helper T cells associated with immune disorders

More than 1,000 small changes in DNA identified that influence age of first period

New study reveals how RNA polymerase opens the transcription bubble in real time

Research reveals how motorized processes shape chromosome structure development

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo