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Study reveals mechanism behind CAR molecule transfer in cancer therapy

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells to other T cells in the tumour microenvironment.

3 Feb 2025

Improving insulin sensitivity with regular mango consumption

The regular consumption of mangoes may improve inflammation, insulin sensitivity, and glucose control.

3 Feb 2025

New findings could make off-the-shelf CAR T cell therapy a reality

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell.

31 Jan 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Hormonal markers could lead to early detection of postpartum depression

Women who go on to develop postpartum depression (PPD) may have characteristic levels of neuroactive steroids, molecules derived from the hormone progesterone, in their blood during the third trimester of pregnancy, according to a new study by researchers at Weill Cornell Medicine and the University of Virginia School of Medicine.

30 Jan 2025

Revolutionizing diabetes care with innovative targets and therapeutic options

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and therapeutic options.

30 Jan 2025

PROTAC technology offers hope for treating castration-resistant prostate cancer

Announcing a new publication for Acta Materia Medica journal. Prostate cancer (PrCa) is the most prevalent urogenital cancer affecting men.

30 Jan 2025

How your immune system ages: Scientists reveal key changes over a lifetime

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, disease resistance, and aging. Their immune age model could help predict immune health and guide early interventions.

30 Jan 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

Genetic predisposition plays a role in how coffee tastes bitter to some more than others

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

29 Jan 2025

Researchers identify brain circuit to reduce anxiety without side effects

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.

28 Jan 2025

Asymptomatic brain metastasis in stage 4 breast cancer requires reevaluation of screening guidelines

A new study led by researchers at Moffitt Cancer Center shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed.

28 Jan 2025

Study shows long-term cannabis use disrupts critical brain processes

Heavy lifetime cannabis use is associated with reduced brain activation in key cognitive regions, particularly during working memory tasks, while recent use may cause temporary cognitive impairments.

28 Jan 2025

T cells grown with new technique offer better cancer defense

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

28 Jan 2025

GLP-1RA initiation linked to new thyroid cancer diagnoses

Researchers investigate the risk of incident thyroid cancer among patients treated with glucagon-like peptide-1 receptor agonists.

28 Jan 2025

Researchers compare cow and camel milk proteomes, focusing on immune proteins and processing

This study compares immune proteins and bioactive peptides in cow and camel milk, highlighting camel milk's lower allergenic potential and therapeutic benefits.

28 Jan 2025

Study unveils critical insights in understanding post-traumatic epilepsy

A new international study has unveiled critical insights in understanding post-traumatic epilepsy (PTE), a condition that can develop following traumatic brain injury. Led by researchers at FutureNeuro, the Research Ireland Centre for Translational Brain Science and RCSI University of Medicine and Health Sciences and published in Theranostics, the study highlights the important role played by a receptor in the brain called P2X7.

27 Jan 2025