Immune System News and Research

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ITA president hosts International Small Bowel Transplant Symposium

Fifty-two year-old Paul McNeel, a fire chief from Leonardtown, Maryland was 37 in 1996 when a sudden health problem caused the loss of his small intestine. Almost all of it had to be surgically removed to save his life. For 13 years after that, McNeel continued to fight fires and stayed alive only because he fed himself a special liquid formula through a tube that went from a port in his chest directly to his heart and into his bloodstream.

15 Sep 2011

Scientists compare complete genome sequences of cowpox virus to prepare a phylogeny

The family of orthopox viruses is generally considered to comprise vaccinia virus, variola virus, cowpox virus and at least six other species. The various pox viruses are named after their usual hosts but this nomenclature may give rise to a false sense of security: most of them seem to have fairly catholic tastes and cowpox is able to infect not only cows but also a variety of other animals, ranging from mice to elephants as well as man.

15 Sep 2011

Scientists report development of three new formulations against methamphetamine abuse

Scientists are reporting development of three promising formulations that could be used in a vaccine to treat methamphetamine addiction - one of the most serious drug abuse problems in the United States.

15 Sep 2011

Differences in lifestyle, tumor genetics linked to head and neck cancer in African Americans

Why are African Americans more likely than Caucasians to be not only diagnosed with head and neck cancer, but also die from the disease? While the answer isn't a simple one, differences in lifestyle, access to care and tumor genetics may, in part, be to blame, according to a new study from Henry Ford Hospital.

15 Sep 2011

Without action to curb antibiotic resistance, some diseases may once again become untreatable

In this Atlantic Magazine opinion piece, Megan McArdle, senior editor at the Atlantic, echoes a warning by the FDA issued in 2001 which stated, "Unless antibiotic resistance problems are detected as they emerge, and actions are taken to contain them, the world could be faced with previously treatable diseases that have again become untreatable, as in the days before antibiotics were developed."

15 Sep 2011

Uterine stem cells could help treat diabetes

Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published in the journal Molecular Therapy.

15 Sep 2011

First effective blood-stage vaccine against malaria

Scientists have identified the first effective blood-stage malaria vaccine, according to a New England Journal of Medicine study from University of Maryland School of Medicine researchers, in collaboration with the University of Bamako in Mali, West Africa, and other partners.

15 Sep 2011

Natural killer white blood cells caught on film

Scientists reveal in more detail than ever before how white blood cells kill diseased tissue using deadly granules, in research published today in PLoS Biology.

14 Sep 2011

Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

Cornell University researchers may have solved a 100-year puzzle: How to safely open and close the blood-brain barrier so that therapies to treat Alzheimer's disease, multiple sclerosis and cancers of the central nervous system might effectively be delivered.

14 Sep 2011

STED microscope reveals that F-actin pervades immunological synapse

Making use of a new "super resolution" microscope that provides sharp images at extremely small scales, scientists have achieved unprecedented views of the immune system in action.

14 Sep 2011

'Achilles' heels' within HCV virus

Hopes for an effective vaccine and treatment against the potentially fatal hepatitis C virus (HCV) have received a major boost following the discovery of two 'Achilles' heels' within the virus.

14 Sep 2011

FDA grants Orphan Drug Designation for Accentia's Revimmune to prevent GVHD

Accentia Biopharmaceuticals, Inc. and its majority-owned subsidiary, Biovest International, Inc., today jointly announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to Revimmune, the Company's proprietary system-of-care based on high-dose administration of Cytoxan, for the prevention of graft-versus-host disease (GVHD) following bone marrow transplant.

14 Sep 2011

Inovio achieves best-in-class immune responses in PENNVAX-B HIV vaccine Phase I study

Inovio Pharmaceuticals, Inc., a leader in the development of synthetic immunogens against cancers and infectious diseases, announced today that it has achieved best-in-class immune responses in a Phase I clinical study of PENNVAX-B, its product for the prevention of the HIV sub-type prevalent in the US and Europe.

14 Sep 2011

Rwanda to treat HIV-positive people in discordant relationships as soon as they test positive

After a landmark study published in May "showed major reductions in HIV transmission among discordant couples due to early treatment," Rwanda has decided to begin treating people in discordant relationships with antiretroviral therapy as soon as they test HIV-positive "as part of a plan to boost national HIV prevention and treatment efforts," PlusNews reports.

14 Sep 2011

IUDs may protect from cervical cancer

According to the results of an international study, coil contraceptive devices might protect women against developing cervical cancer even though they don't stop the infection that commonly leads to the disease.

14 Sep 2011

Computer models that predict response to treatment

Details of computer models that can predict the chances of a patient responding to their HIV drugs with 80% accuracy are published today in the journal AIDS. The models were developed by the HIV Resistance Response Database Initiative (RDI) using almost half a million pieces of data from approximately 6,000 clinical cases from hundreds of clinics around the world. The models are now available online as part of an experimental treatment support tool, HIV-TRePS.

14 Sep 2011

Intrauterine devices may lower risk of cervical cancer among users, study shows

Contraceptive intrauterine devices (IUDs), also called coils, "might actually protect women against developing cervical cancer even though they don't stop the infection that commonly leads to the disease," according to a study published Tuesday in the journal Lancet Oncology, Reuters reports.

14 Sep 2011

Intrauterine devices may protect against cervical cancer

Intrauterine devices (IUDs) may protect against cervical cancer. This is the conclusion of the broadest epidemiological study to date in which has participated the research group in Viruses and Cancer of IDIBELL, published at The Lancet Oncology.

14 Sep 2011

Positive data from NovaDigm's NDV-3 vaccine program to be presented at ICAAC conference

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced that the Company will present positive data for its NDV-3 vaccine program at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), taking place September 17-20, 2011 in Chicago, IL.

13 Sep 2011

ImmunoCellular announces updated long-term data from ICT-107 Phase I trial on GBM

ImmunoCellular Therapeutics, Ltd., a biotechnology company focused on the development of novel immune-based cancer therapies, today announced updated long-term data from a Phase I clinical trial of ICT-107, the Company's lead cancer vaccine candidate for the treatment of glioblastoma multiforme (GBM), the most common and aggressive form of brain cancer.

13 Sep 2011

Immune System News and Research

ITA president hosts International Small Bowel Transplant Symposium

Scientists compare complete genome sequences of cowpox virus to prepare a phylogeny

Scientists report development of three new formulations against methamphetamine abuse

Differences in lifestyle, tumor genetics linked to head and neck cancer in African Americans

Without action to curb antibiotic resistance, some diseases may once again become untreatable

Uterine stem cells could help treat diabetes

First effective blood-stage vaccine against malaria

Natural killer white blood cells caught on film

Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

STED microscope reveals that F-actin pervades immunological synapse

'Achilles' heels' within HCV virus

FDA grants Orphan Drug Designation for Accentia's Revimmune to prevent GVHD

Inovio achieves best-in-class immune responses in PENNVAX-B HIV vaccine Phase I study

Rwanda to treat HIV-positive people in discordant relationships as soon as they test positive

IUDs may protect from cervical cancer

Computer models that predict response to treatment

Intrauterine devices may lower risk of cervical cancer among users, study shows

Intrauterine devices may protect against cervical cancer

Positive data from NovaDigm's NDV-3 vaccine program to be presented at ICAAC conference

ImmunoCellular announces updated long-term data from ICT-107 Phase I trial on GBM

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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