Amyotrophic Lateral Sclerosis News and Research

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New target identified for potential ALS therapy

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects motor neurons.

10 Sep 2024

New immunotherapy approach shows promise for minimizing spinal cord injury damage

WashU Medicine researchers have designed, in mice, an approach to minimizing the damage from a spinal cord injury through the use of engineered immune cells.

4 Sep 2024

PQBP3 protein found to play key role in aging and brain disorders

In a recent study published online on August 5 2024 in The EMBO Journal, researchers from Tokyo Medical and Dental University (TMDU) in Japan have uncovered a crucial piece of this puzzle by focusing on the role of a single nucleolar protein.

3 Sep 2024

Major trial to test multiple drugs for progressive supranuclear palsy

A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start.

3 Sep 2024

Breakthrough miniaturized brain-machine interface enables brain-to-text communication

Researchers from EPFL have developed a next-generation miniaturized brain-machine interface capable of direct brain-to-text communication on tiny silicon chips.

27 Aug 2024

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) announced today a new research grant awarded to Daniela C. Zarnescu, Ph.D., Professor of Cellular and Molecular Physiology at Penn State University College of Medicine, in collaboration with Jon Njardarson, Ph.D., Professor at the University of Arizona.

8 Aug 2024

New technique reveals abnormalities in motor neurone disease

Pathological abnormalities associated with motor neurone disease have been identified using a new technique developed at the University of Birmingham.

8 Aug 2024

Elevated metal levels in plasma and urine associated with greater ALS risk and shorter survival

People with higher levels of metals found in their blood and urine may be more likely to be diagnosed with - and die from - amyotrophic lateral sclerosis, or ALS, a University of Michigan-led study suggests.

6 Aug 2024

Researchers identify key genetic variants linked to ALS recovery

Though exceedingly rare, some people diagnosed with amyotrophic lateral sclerosis (ALS) partially or fully recover from the lethal neurodegenerative disease.

30 Jul 2024

Experimental cancer drug may help clear HIV from infected cells in the brain

An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new Tulane University study.

25 Jul 2024

Researchers identify a potential therapeutic target for advanced multiple sclerosis

Researchers from Kyushu University have identified a potential therapeutic target for the treatment of advanced multiple sclerosis (MS), a potentially disabling condition associated with the central nervous system.

25 Jul 2024

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego - a discovery that could lead to therapies for patients with other neurological conditions.

25 Jul 2024

Concussions in retired rugby players linked to higher neurodegenerative disease biomarkers

A study in the International Journal of Molecular Sciences reveals that retired rugby players with a history of concussions exhibit significant differences in biomarkers associated with neurodegenerative diseases compared to non-contact sports participants.

21 Jul 2024

ARPP21 gene mutation could be the cause of ALS

Researchers from the Neuromuscular Diseases Group and the Dementia Neurobiology Group of the Sant Pau Research Institute (IR Sant Pau) and the Memory Unit of the Sant Pau Hospital, led by neurologist Dr. Ricard Rojas-García, have identified a new mutation in the ARPP21 gene that could be the cause of Amyotrophic Lateral Sclerosis (ALS), a devastating neurodegenerative disease.

11 Jul 2024

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

There's only one U.S. Food and Drug Administration-approved therapy for an inherited retinal disease, and dozens of retinitis pigmentosa (RP) genes for which no therapy is available.

8 Jul 2024

Decoding the viscoelastic properties of biomolecular condensates

Biomolecular condensates are membraneless hubs of condensed proteins and nucleic acids within cells, which researchers are realizing are tied to an increasing number of cellular processes and diseases.

2 Jul 2024

Study finds promising new target for the treatment of Alzheimer's disease

A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State.

2 Jul 2024

Moderate physical activity may be linked to reduced risk of ALS later in life

Moderate levels of physical activity and fitness may be linked to a reduced risk of amyotrophic lateral sclerosis (ALS) later in life, according to a new study published in the June 26, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2024

ALS: Newly discovered subtypes and sex differences create new approaches for drugs

Amyotrophic lateral sclerosis, ALS for short, is a mysterious neurodegenerative disease that is almost always fatal.

21 Jun 2024

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

In a study with 991 adults, scientists at DZNE show that the most common forms of frontotemporal dementia (FTD) as well as the neurological diseases amyotrophic lateral sclerosis (ALS) and progressive supranuclear palsy (PSP) can be recognized by blood testing.

18 Jun 2024

Amyotrophic Lateral Sclerosis News and Research

New target identified for potential ALS therapy

New immunotherapy approach shows promise for minimizing spinal cord injury damage

PQBP3 protein found to play key role in aging and brain disorders

Major trial to test multiple drugs for progressive supranuclear palsy

Breakthrough miniaturized brain-machine interface enables brain-to-text communication

C-Path supports innovative ALS, neurodegenerative disease research with new grant

New technique reveals abnormalities in motor neurone disease

Elevated metal levels in plasma and urine associated with greater ALS risk and shorter survival

Researchers identify key genetic variants linked to ALS recovery

Experimental cancer drug may help clear HIV from infected cells in the brain

Researchers identify a potential therapeutic target for advanced multiple sclerosis

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

Concussions in retired rugby players linked to higher neurodegenerative disease biomarkers

ARPP21 gene mutation could be the cause of ALS

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

Decoding the viscoelastic properties of biomolecular condensates

Study finds promising new target for the treatment of Alzheimer's disease

Moderate physical activity may be linked to reduced risk of ALS later in life

ALS: Newly discovered subtypes and sex differences create new approaches for drugs

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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