Atomic Force Microscopy News and Research

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Atomic force microscopy is a type of scanning probe microscopy used to image the surface of a substance, but at an atomic level. It can map the surface structure of different substances to understand how different structures interact with each other. This is done using a cantilever, which is similar to a vinyl record needle.

Simple physics may play key role in helping the body to fight infection

Simple physics may play a larger role than previously thought in helping control key bodily processes - such as how the body fights infection.

11 Feb 2016

AFM Images of microvilli on live cells taken for the first time

In a just released article in the Journal of Molecular Recognition, Dr. Hermann Schillers et al. report the first visualization of individual microvilli on living cells with atomic force microscopy.

From Bruker Nano Surfaces and Metrology 1 Oct 2015

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Viruses are able to redirect the functioning of cells in order to infect them. Inspired by their mode of action, scientists from the CNRS and Université de Strasbourg have designed a "chemical virus" that can cross the double lipid layer that surrounds cells, and then disintegrate in the intracellular medium in order to release active compounds.

29 Aug 2015

New type of mycovirus can cause aspergillosis in humans

Researchers, led by Dr Robert Coutts, Leverhulme Research Fellow from the School of Life and Medical Sciences at the University of Hertfordshire, and Dr Ioly Kotta-Loizou, Research Associate at Imperial College, have discovered a completely novel type of mycovirus.

29 Jul 2015

New finding could help change pharmaceutical treatment of neurodegenerative diseases

Diseases like Alzheimer's are caused when proteins aggregate and clump together. In a world first, EPFL scientists have successfully distinguished between the disease-causing aggregation forms of proteins.

28 Jul 2015

Researchers map physical properties of live breast cancer cells using advanced AFM technology

Researchers who developed a high-speed form of atomic force microscopy have shown how to image the physical properties of live breast cancer cells, for the first time revealing details about how deactivation of a key protein may lead to metastasis.

30 Jun 2015

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Increased vascular stiffness has been identified as an important part of hypertension in aging adults. Previous studies of aortic stiffness have focused on changes in structural proteins that alter the properties of vascular walls causing them to become rigid.

11 May 2015

JPK reports on the use of the NanoWizard® 3 AFM system at the Hebrew University of Jerusalem

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the use of their NanoWizard® AFM system in the Institute of Chemistry of the Hebrew University of Jerusalem...

From Bruker BioAFM 14 Apr 2015

Researchers develop new AFM system for imaging structural dynamics of living cells, neurons

While progress has been made over the past decades in the pursuit to optimize atomic force microscopy (AFM) for imaging living cells, there were still a number of limitations and technological issues that needed to be addressed before fundamental questions in cell biology could be address in living cells.

18 Mar 2015

Bielefeld University chemists develop copper molecule that could help prevent spread of cancer

Chemists at Bielefeld University have developed a molecule containing copper that binds specifically with DNA and prevents the spread of cancer. First results show that it kills the cancer cells more quickly than cisplatin - a widely used anti-cancer drug that is frequently administered in chemotherapy.

2 Mar 2015

Bruker-sponsored sixth AFM Biomed conference highlights increasing impact of AFM in biological applications

Bruker recently sponsored the sixth AFM BioMed International Meeting on AFM in Life Sciences and NanoMedicine. Held last month at the Sanford Consortium for Regenerative Medicine in La Jolla, CA, the conference brought together more than 125 scientists from around the world.

From Bruker Nano Surfaces and Metrology 26 Feb 2015

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

Christian Griesinger, director of the NMR-based Structural Biology department at the Max-Planck Institute for Biophysical Chemistry, talks about his research into neurodegenerative diseases using NMR to examine the dynamics of disordered proteins.

From Bruker BioSpin Group 23 Feb 2015

Park Systems announces innovations in bio cell analysis with the launch of Park NX-Bio

Park Systems, a leading manufacturer of atomic force microscopy (AFM) and nanoscale metrology products, proudly introduces Park NX-Bio, a powerful 3-in-1 bio-research tool that uniquely combines scanning ion conductance microscopy (SICM) with AFM and an inverted optical microscope (IOM) on the same platform.

29 Jan 2015

Bruker Launches BioScope Resolve™ at the Sixth AFM BioMed Conference

Bruker unveiled the BioScope Resolve™, a biological atomic force microscope (bioAFM), at the sixth AFM BioMed Conference. The BioScope Resolve™ features excellent resolution imaging and comprehensive cell mechanics capabilities, and can be used with an inverted optical microscope (IOM).

From Bruker Nano Surfaces and Metrology 17 Dec 2014

Scientists reveal how bacterial nanodrills enter into our cells to kill them

A team of scientists has revealed how certain harmful bacteria drill into our cells to kill them. Their study shows how bacterial 'nanodrills' assemble themselves on the outer surfaces of our cells, and includes the first movie of how they then punch holes in the cells' outer membranes.

3 Dec 2014

Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Cancer diagnostics and treatment options could be drastically improved with the creation of a 'designer' nanodevice being developed by researchers from the UK, Italy, the US and Argentina.

22 Oct 2014

Researchers discover new details of how autoantibodies destroy healthy cells in skin

University at Buffalo researchers and colleagues studying a rare, blistering disease have discovered new details of how autoantibodies destroy healthy cells in skin.

11 Sep 2014

NanoTracker™ Optical Tweezers system used at Leiden University to study the organisation of genomic DNA

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the use of the NanoTracker™ Optical Tweezers system in the Laboratory of Molecular Genetics in the Leiden Institute of Chemistry at Leiden University.

9 Sep 2014

Scientists develop 3-D artificial enzyme cascade that mimics biochemical pathway using DNA molecules

Using molecules of DNA like an architectural scaffold, Arizona State University scientists, in collaboration with colleagues at the University of Michigan, have developed a 3-D artificial enzyme cascade that mimics an important biochemical pathway that could prove important for future biomedical and energy applications.

26 May 2014

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

Alzheimer's is a progressive brain disease that affects older adults, slowly destroys their memories and may cause dementia. According to estimates from the National Institutes of Health (NIH), the disease may affect as many as 5.1 million Americans.

22 May 2014

Atomic Force Microscopy News and Research

Further Reading

Simple physics may play key role in helping the body to fight infection

AFM Images of microvilli on live cells taken for the first time

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

New type of mycovirus can cause aspergillosis in humans

New finding could help change pharmaceutical treatment of neurodegenerative diseases

Researchers map physical properties of live breast cancer cells using advanced AFM technology

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

JPK reports on the use of the NanoWizard® 3 AFM system at the Hebrew University of Jerusalem

Researchers develop new AFM system for imaging structural dynamics of living cells, neurons

Bielefeld University chemists develop copper molecule that could help prevent spread of cancer

Bruker-sponsored sixth AFM Biomed conference highlights increasing impact of AFM in biological applications

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

Park Systems announces innovations in bio cell analysis with the launch of Park NX-Bio

Bruker Launches BioScope Resolve™ at the Sixth AFM BioMed Conference

Scientists reveal how bacterial nanodrills enter into our cells to kill them

Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Researchers discover new details of how autoantibodies destroy healthy cells in skin

NanoTracker™ Optical Tweezers system used at Leiden University to study the organisation of genomic DNA

Scientists develop 3-D artificial enzyme cascade that mimics biochemical pathway using DNA molecules

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

How to use Atomic Force Microscopy in Life Sciences eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo