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New studies reveal hidden control hub for MYC-driven cancers

In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, PhD, associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham Prebys Medical Discovery Institute, establish a unified framework that governs one of cancer's most powerful master regulators.

19 Aug 2026

A single blood test could offer a glimpse of disease risk years in advance

Machine learning-derived cellular aging clocks mapped more than 7,000 plasma proteins to over 40 cell types, revealing marked differences in how individual cell populations age. These blood-based signatures were associated with future risks of Alzheimer’s disease, ALS, lung cancer, type 2 diabetes, and mortality across follow-up extending to 15 years.

19 Aug 2026

New genetic risk score uncovers hidden type 1 diabetes cases

Incorporating a genetic risk score into standard testing for a genetic form of diabetes which affects young people could identify hidden type 1 diabetes in around one in five patients with a negative genetic test.

19 Aug 2026

Gene editing fails to protect beta-cell transplants from rejection

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

19 Aug 2026

Study uncovers molecular mechanism behind age-associated skin inflammation

As we age, the skin loses part of its ability to regenerate, heal wounds, and maintain an effective barrier against the outside world.

19 Aug 2026

New research uncovers unique genetic links to eating disorders

New research led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, in collaboration with an international partnership of researchers, has, for the first time, compared the genetics of people with binge eating versus those without any eating disorder.

19 Aug 2026

UVA researchers find how postoperative delirium may set the stage for dementia

UVA Health researchers have discovered how a form of delirium that often strikes older patients after surgery may set the stage for dementia – and identified a drug that could reverse the underlying brain changes.

18 Aug 2026

Researchers develop new tool to estimate a cell's biological age

Researchers at Karolinska Institutet and Stockholm University have developed a new tool that estimates a cell's biological age by analyzing its gene activity.

18 Aug 2026

First high-resolution cell-by-cell map tracks tomato root and fungal partnership

Scientists at VIB and Ghent University have produced the first high-resolution, cell-by-cell map of how tomato roots respond to colonization by arbuscular mycorrhizal fungi.

18 Aug 2026

Deep-learning tissue clocks reveal how organs age and leave disease-linked signals in blood

Deep learning applied to more than 25,000 histopathology slides revealed tissue-specific structural signatures of biological aging that tracked telomere attrition, pathology, comorbidity, and molecular changes more closely than chronological age alone.

18 Aug 2026

Researchers uncover hidden function of known tuberculosis bacterium gene

The complete genome for the tuberculosis bacterium was sequenced and published in 1998. Since then, scientists have deciphered about two-thirds of TB's genes. Or have they?

17 Aug 2026

Computational pipeline uncovers subtype specific targets for cervical cancer

A new study presents a multi-layered strategy for identifying cell-surface targets that could help guide more precise antibody-drug conjugate (ADC) development for cervical cancer, with different targets showing distinct potential across tumor subtypes.

17 Aug 2026

New genetic mutations linked to malaria drug resistance discovered

Researchers searching for genetic clues to the growing problem of malaria drug resistance identified new mutations associated with the parasite's decreased susceptibility to current treatment.

17 Aug 2026

Sprint exercise sends a very different molecular signal through the body

Sprint-interval exercise triggers a much larger and faster shift in circulating proteins and metabolites than moderate-intensity exercise, revealing distinct patterns of predicted communication between organs. The findings suggest that exercise intensity shapes systemic molecular signaling, with skeletal muscle and adipose tissue emerging as potential source and target tissues linked to cardiometabolic health.

16 Aug 2026