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Integrating pharmacogenomics into everyday clinical practice can transform patient care

Pharmacogenomics studies how individuals respond to drugs based on their genetic code. Using that knowledge to guide prescribing in routine care could lead to better outcomes for patients and save money for health systems.

26 May 2025

New genetic database sheds light on Brazil’s ancestry and disease risks

Since the human genome was first sequenced in 2003, the world's scientific community has been racing to decipher this "book" written in an alphabet of four letters.

15 May 2025

Targeting METTL3 may offer new hope for oral cancer treatment

A new research paper was published in Oncotarget, Volume 16, on May 8, 2025, titled "METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis."

11 May 2025

Scientists build world's most accessible gut bacteria collection to unlock health and disease clues

Researchers have developed the Human Intestinal Bacteria Collection (HiBC), comprising 340 gut bacterial strains from 198 species, including 29 newly described taxa, made publicly available for functional microbiome research.

7 May 2025

Baby's first steps influenced by genetics

The age at which babies take their first steps is strongly influenced by their genes, according to new research from the University of Surrey.

7 May 2025

RNA editing enzyme found to trigger neuroinflammation in Parkinson's

Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage.

3 May 2025

Predictive model could improve treatment decisions for advanced pancreatic cancer patients

Researchers in Japan have developed a predictive model that could improve treatment decisions for advanced pancreatic cancer patients.

28 Apr 2025

New DNA mapping technology uncovers genetic clues to rare diseases

Cutting-edge DNA mapping technology identified new genetic information that can help researchers decipher more genetic diseases, a new study found.

25 Apr 2025

IL-17A identified as a potential driver of cancer in familial adenomatous polyposis

Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer.

25 Apr 2025

New tool simplifies genomic research and boosts medical breakthroughs

A University of Virginia School of Medicine scientist and collaborators have developed a much-needed new tool to increase the efficiency of genomic research and accelerate the development of new ways to improve human health.

16 Apr 2025

Humanized liver organoids double survival rate in rodent models

One reason why our livers excel at clearing waste from our blood system is that the organ functions according to three key "zones" that perform specific major tasks.

16 Apr 2025

Multi-omics analysis uncovers molecular drivers of non-viral liver cancer development

Researchers discover that inflammation and aging contribute to non-viral liver cancer development. Green tea's role in reversing some of the pathway dysregulation that may contribute to the cancer development and other therapies explored.

15 Apr 2025

Can gut microbes help prevent Alzheimer’s?

A comprehensive review explores how gut microbiota diversity and fitness influence Alzheimer’s disease (AD) risk through neuroinflammation, amyloid and tau pathology, and blood-brain barrier dysfunction. It highlights the therapeutic potential of probiotics, dietary interventions, and omics technologies in restoring microbial balance and preventing neurodegeneration.

13 Apr 2025