Glutamine News and Research

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Glutamine is an amino acid used in nutrition therapy. It is also being studied for the treatment of diarrhea caused by radiation therapy to the pelvis.

Chemical changes in the brain may be associated with unexplained motor symptoms

A new study finds that people who have movement problems, symptoms that cannot be explained by an underlying disease, may have chemical changes in specific areas of the brain.

6 Jun 2019

Tumor-fighting combination targets aggressive form of brain cancer

Researchers have paired a specialized diet and a tumor-fighting drug and found the non-toxic combination helps to destroy the two major cells found in an aggressive form of brain cancer, the team reports in the online edition of the Nature group journal Communications Biology.

31 May 2019

Mining 25 years of data reveals new insights into predicting the age of onset for Huntington disease

Investigators at the University of British Columbia/Centre for Molecular Medicine & Therapeutics and BC Children's Hospital have examined more than 25 years of data to reveal new insights into predicting the age of onset for Huntington disease.

18 May 2019

Brazilian researchers develop new strategy to starve triple negative breast cancer cells

A team of Brazilian researchers has developed a strategy that slows the growth of triple negative breast cancer cells by cutting them off from two major food sources.

13 May 2019

Johns Hopkins researchers uncover role of neurotransmitter in the spread of aggressive cancers

Using human cancer cells, tumor and blood samples from cancer patients, researchers at Johns Hopkins Medicine have uncovered the role of a neurotransmitter in the spread of aggressive cancers. Neurotransmitters are chemical "messengers" that transmit impulses from neurons to other target cells.

25 Apr 2019

Researchers identify cause of inherited metabolic disorder

A new study from BC Children's Hospital, the University of British Columbia (UBC) and an international team of researchers published in the New England Journal of Medicine is the first to identify a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder.

16 Apr 2019

Scientists find highly promising therapeutic target for leukemia

Cancer cells consume sugar at a higher rate than healthy cells, but they're also hungry for amino acids, the building blocks of proteins and other biomolecules.

13 Mar 2019

Researchers report promising advance in the search for new class of antidepressants

In experiments with mice, researchers at Johns Hopkins Medicine report a promising advance in the search for a new class of drugs to treat major depression.

8 Feb 2019

Fueling macrophages with energy to attack and eat cancer cells

Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. Now researchers at the Abramson Cancer Center of the University of Pennsylvania say they've identified how to fuel macrophages with the energy needed to attack and eat cancer cells.

21 Jan 2019

New findings bring about better understanding of many cancers' metabolic needs

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism.

10 Jan 2019

Study elucidates how essential amino acid in humans acts as growth signal for cells

A recent study from the Laxman lab elucidates how a small metabolite and amino acid, methionine, acts as a growth signal for cells, by setting into motion a metabolic program for cell proliferation.

7 Jan 2019

New research examines cancer metabolism at multiple scales

No matter what form cancer takes in the body, it starts at the cellular level and grows via metabolism run amok.

21 Dec 2018

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target important enzymes fueling a range of subtypes, including BCRA-mutated and triple negative cancers.

7 Dec 2018

Restricting cancer metabolism could make oncolytic viruses more effective at attacking tumors

Restricting the ability of cancer cells to metabolise sugar could make oncolytic viruses more effective at attacking them, suggests a study published today in the journal Cancer Research.

29 Nov 2018

New form of therapy may stop or reverse progressive vision loss

A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness.

1 Nov 2018

Metabolic signatures in blood may help in earlier diagnosis of autism, shows research

Metabolic signatures in the blood of children with autism spectrum disorder may lead to earlier diagnosis of the condition for some children, according to newly published research. These biochemical signatures provide insight into how the body metabolizes certain amino acids important to typical neurodevelopment.

6 Sep 2018

Wyss researchers create model of the BBB-brain interface using microfluidically linked Organ Chips

The human brain, with its 100 billion neurons that control every thought, word, and action, is the most complex and delicate organ in the body. Because it needs extra protection from toxins and other harmful substances, the blood vessels that supply the brain with oxygen and nutrients are highly selective about which molecules can cross from the blood into the brain and vice versa.

22 Aug 2018

Ablating the mutant p53 gene in mice with colorectal cancer inhibits tumor growth

By genetically manipulating and removing the most common mutant form of the p53 gene that promotes colorectal cancer in humans, an international team of scientists demonstrated that this therapy reduces tumor growth and tissue invasion.

15 Aug 2018

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

When tissue is damaged, one of the body's first inflammatory immune-system responders are macrophages, cells which are commonly thought of as "construction workers" that clear away damaged tissue debris and initiate repair.

28 Jul 2018

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

UCSF Benioff Children's Hospital Oakland clinical researchers, in conjunction with other sickle cell centers and scientists at Emmaus Life Sciences, Inc., have demonstrated that therapy with L-Glutamine reduced the frequency of pain episodes in both pediatric and adult patients with sickle cell disease.

27 Jul 2018