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Circulating microparticle proteins predict placenta accreta spectrum before delivery

A recent study published in the journal Scientific Reports reported that circulating microparticle (CMP) proteins predict pregnancies complicated by placenta accreta spectrum (PAS).

9 Jan 2023

New insights into the bioavailability and hepatoxicity risk of neonicotinoids

Researchers quantified the residues of eight neonicotinoids in human bile samples to understand the association between internal neonicotinoid exposure and hepatotoxic outcomes.

4 Jan 2023

Scientists explore synthesis of griffithsin in cell-free systems

A new study described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein.

28 Dec 2022

Scientists suggest vibrational spectroscopy and nuclear magnetic resonance to evaluate drug concentrations

Scientists at Baltic Federal University have suggested evaluating concentration and chemical composition of drugs by means of vibrational spectroscopy and nuclear magnetic resonance instead of conventional complex approaches.

20 Dec 2022

Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

Researchers used sheep, a ruminant mammal, to obtain polyclonal immunoglobulins (IgGs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Dec 2022

Pumpkin byproducts exhibit antioxidant and antimicrobial activity

Researchers characterized the bioactive agents in the food industry byproducts of pumpkins.

2 Dec 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Isolated monoclonal antibodies targeting SARS-CoV-2 S1/S2 cleavage effective against Delta and Omicron

Isolated monoclonal antibodies neutralize SARS-CoV-2 Delta and Omicron variants.

28 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

What are the current challenges and future directions of mRNA nanomedicine?

Researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations and future directions to improve the clinical efficacy of mRNA nanomedicine.

15 Nov 2022

Metabolomic study of genetic regulation of biochemical individuality

Researchers systematically investigated the genetic makeup of nearly 20,000 women and men in terms of >900 metabolites.

15 Nov 2022

Gut colonization by proteobacteria modulates mice’s neurobehavioral response to cocaine

A new study revealed that gut colonization by proteobacteria modulates cocaine neurobehavioral response in mice.

3 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

Scientists reveal anti-inflammatory molecules that play an important role in aging

Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists reveal another factor implicated in the aging process-;a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects.

31 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes-;or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

Associations between potential endocrine-disrupting chemicals and female fertility in women attending fertility clinics

Researchers explored the correlation between female fertility and chemical mixtures.

30 Sep 2022

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

A recent study explored the diet-exercise-gut microbiome dynamics in male bodybuilders.

30 Sep 2022

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

New Jersey Institute of Technology researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based drugs, such as therapeutic monoclonal antibodies being developed to treat a variety of diseases, from cancers to infectious diseases.

27 Sep 2022

What are the effects of pesticides on neonates' health?

A new study explores the impact of pesticide exposure in neonates, reviewing current literature while evaluating the research methods used in this area.

20 Sep 2022

Liquid Chromatography News and Research

Circulating microparticle proteins predict placenta accreta spectrum before delivery

New insights into the bioavailability and hepatoxicity risk of neonicotinoids

Scientists explore synthesis of griffithsin in cell-free systems

Scientists suggest vibrational spectroscopy and nuclear magnetic resonance to evaluate drug concentrations

Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

Pumpkin byproducts exhibit antioxidant and antimicrobial activity

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Isolated monoclonal antibodies targeting SARS-CoV-2 S1/S2 cleavage effective against Delta and Omicron

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

What are the current challenges and future directions of mRNA nanomedicine?

Metabolomic study of genetic regulation of biochemical individuality

Gut colonization by proteobacteria modulates mice’s neurobehavioral response to cocaine

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Scientists reveal anti-inflammatory molecules that play an important role in aging

Metabolite discovery offers a potential way to address metabolic conditions

Associations between potential endocrine-disrupting chemicals and female fertility in women attending fertility clinics

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

What are the effects of pesticides on neonates' health?

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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