Metformin News and Research

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Metformin is the active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body’s use of the glucose. Metformin is a type of antidiabetic agent.

Researchers explore a case of diabetic ketoacidosis in patient with atezolizumab-induced autoimmune diabetes

In a new publication from Cardiovascular Innovations and Applications, Sharen Lee and Gary Tse from Laboratory of Cardiovascular Physiology, Hong Kong, HKG, China, Second Hospital of Tianjin Medical University, Tianjin, China and Xiamen Cardiovascular Hospital, Xiamen, China consider a case of atezolizumab-induced autoimmune diabetes mellitus presenting with diabetic ketoacidosis.

29 Mar 2021

Scientists seek Covid treatment answers in cheap, older drugs

Could a decades-old antidepressant be a secret weapon against covid? A few scientists think so, after two small studies showed that fluvoxamine, typically prescribed for obsessive-compulsive disorder, prevented serious illness in all participants who took the pills soon after developing symptoms.

29 Mar 2021

Antidiabetic drug could help reduce chronic inflammation in people living with HIV

Metformin, a drug used to treat type-2 diabetes, could help reduce chronic inflammation in people living with HIV (PLWH) who are being treated with antiretroviral therapy (ART), according to researchers at the University of Montreal Hospital Research Centre.

18 Mar 2021

Study: Semaglutide drug promotes weight loss in patients with type 2 diabetes

Patients with type 2 diabetes that were treated with a weekly injection of the breakthrough drug Semaglutide were able to achieve an average weight loss of nearly 10kg, according to a new study published in The Lancet today.

3 Mar 2021

Study: Body produces large amounts of GDF15 hormone during extended bouts of vigorous exercise

A drug that helps us to eat less could help the more than 650 million people around the world who live with obesity.

17 Feb 2021

New study to evaluate the effectiveness of drugs on preventing COVID-19 progression

McMaster University researchers are leading a large international study to test drugs to treat COVID-19 patients.

9 Feb 2021

Oncotarget publishes new research on geroscience

Dr. Mikhail V. Blagosklonny, M.D., Ph.D., Editor-in-Chief of Oncotarget, and Professor, at Roswell Park Cancer Institute, published "The goal of geroscience is life extension" which was selected as the Featured Cover Paper for Volume 12 Issue 3 and reported that although numerous drugs seemingly extend healthspan in mice, only a few extend lifespan in mice and only one does it consistently.

4 Feb 2021

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

A new study by researchers in China and the U.S. describes a round-up of the effects of commonly used hypoglycemic drugs on the outcomes of COVID-19 in diabetic patients.

1 Feb 2021

New automated measurement system to assess healthy lifespans using nematodes

A research group from Kumamoto University (Japan) has developed an automated measurement system to assess healthy lifespans using nematodes (C. elegans).

27 Jan 2021

New compound could lead to a new class of diabetes drugs

Research led by The Ohio State University Wexner Medical Center and College of Medicine identified a new compound that might serve as a basis for developing a new class of drugs for diabetes.

27 Jan 2021

Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes

Use of the diabetes drug metformin -- before a diagnosis of COVID-19 -- is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham.

15 Jan 2021

Machine-learning method can crunch data to find new uses for existing drugs

Scientists have developed a machine-learning method that crunches massive amounts of data to help determine which existing medications could improve outcomes in diseases for which they are not prescribed.

4 Jan 2021

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Diabetes is a known risk factor for morbidity and mortality related to COVID-19. In diabetes patients, rare but severe complications, like the potentially lethal condition diabetic ketoacidosis (DKA), can arise when illness or certain conditions prevent cells from receiving enough glucose to fuel their functioning.

28 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

UH researcher examines whether early drug intervention can curb weight gain in mentally ill children

A University of Houston pharmacological researcher believes that prescribing the drug Metformin for children and teens as soon as they are diagnosed with mental illnesses, like bipolar disorder and schizophrenia, may save them from gaining an enormous amount of weight.

16 Dec 2020

Metformin News and Research

Further Reading

Researchers explore a case of diabetic ketoacidosis in patient with atezolizumab-induced autoimmune diabetes

Scientists seek Covid treatment answers in cheap, older drugs

Antidiabetic drug could help reduce chronic inflammation in people living with HIV

Study: Semaglutide drug promotes weight loss in patients with type 2 diabetes

Study: Body produces large amounts of GDF15 hormone during extended bouts of vigorous exercise

New study to evaluate the effectiveness of drugs on preventing COVID-19 progression

Oncotarget publishes new research on geroscience

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

New automated measurement system to assess healthy lifespans using nematodes

New compound could lead to a new class of diabetes drugs

Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes

Machine-learning method can crunch data to find new uses for existing drugs

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Researchers demonstrate potential preventive treatment for Crohn's disease

UH researcher examines whether early drug intervention can curb weight gain in mentally ill children

Study shows metformin can significantly reduce COVID-19 death risks in women

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

Study shows oxidant hydrogen peroxide can actually slow down cell ageing

Drug combo for Type 2 diabetes continues to stay effective after two years of treatment

Study offers renewed hope for children suffering from myofibrillar myopathies

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