Pulmonary arterial hypertension (PAH) is a condition involving high blood pressure and structural changes in the walls of the pulmonary arteries, which are the blood vessels that connect the right side of the heart to the lungs. Affecting people of all ages and ethnic backgrounds - but most commonly found in young women of child-bearing years - the disease has historically been chronic and incurable, with a poor survival rate. PAH is often not diagnosed in a timely manner because its early symptoms can be confused with those of many other pulmonary and respiratory conditions. Symptoms include shortness of breath, extreme fatigue, dizziness, fainting, swollen ankles and legs and chest pain (especially during physical activity). With proper diagnosis, there are currently several therapies to alleviate symptoms and improve quality of life for PAH patients. The key is to find a PAH specialist and pursue immediate treatment.
A new study published in the journal Nature Communications in February 2020 shows that secretions from stem cells in the lung can be utilized to nebulize injured lungs due to several types of lung fibrosis in rats and mice. This could well result in the development of less invasive and more effective therapies for lung fibrosis.
A research team led by Dr. Yunching Chen and Tsai-Te Lu of National Tsing Hua University have recently developed a new treatment for cancer, in which blood vessels within malignant tumors are normalized by injecting a specially developed nanodelivery system for nitric oxide (NanoNO), which also facilitates the delivery of cancer drugs and immunocytes into the tumor.
A team of researchers has found that the microflora of bacteria within the gut of humans could be a contributor to the development of pulmonary arterial hypertension (PAH). The study titled, "Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension," in the latest issue of the American Heart Association's journal Hypertension.
Researchers have identified a distinct collection of bacteria found in the gut that may contribute to and predict the development of pulmonary arterial hypertension, according to new research published today in the American Heart Association's journal Hypertension.
The invention of interactive map applications has revolutionized wayfinding, providing an unprecedented level of information far beyond what printed road maps can offer.
Pulmonary hypertension is a type of high blood pressure that affects the lungs of both animals and people. When tiny vessels in the lungs become narrowed or blocked, it becomes harder for blood to flow through and can cause the heart to weaken or fail.
International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.
The European Society of Cardiology Guidelines on acute pulmonary embolism are published online today in European Heart Journal, and on the ESC website. They were developed in collaboration with the European Respiratory Society.
Researchers at the Stanford University School of Medicine have found that inflammation in the lungs of rats, triggered by something as simple as the flu, may wake up a silent genetic defect that causes sudden onset cases of pulmonary hypertension, a deadly form of high blood pressure in the lungs.
Left ventricular assist devices, or LVADs, have been shown to help leaky mitral valves that create significant regurgitation, but a new study questions the presumption that all's well with the mitral valve after a patient receives a LVAD.
UW Medicine's lung-transplant team, the only such providers in the Pacific Northwest, performed their 1,000th transplant on July 7, 2019. Ten other U.S. programs have reached such a milestone.
An international team of researchers are seeking to explore the heart at a depth that was previously impossible.
More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12 in Journal of Clinical Oncology.
Owlstone Medical, the global leader in Breath Biopsy for applications in early disease detection and precision medicine today announces a strategic collaboration with Actelion Pharmaceuticals Ltd, one of the Janssen Pharmaceutical Companies of Johnson & Johnson and a global leader in pulmonary arterial hypertension, to discover and validate a breath-based test to help facilitate the early diagnosis of pulmonary hypertension and its subtypes.
Patients with chronic kidney disease, and dialysis patients especially, have a significantly higher cardiovascular morbidity and mortality than healthy people. Kidney transplantation is the best renal replacement therapy available.
In a study published in Science Advances magazine, researchers from the University of California, Irvine have captured, for the first time, the full-length structure of the rod photoreceptor phosphodiesterase 6 (PDE6), an enzyme that plays an indispensable role in human vision.
Clinicians should use echocardiography, an ultrasound that shows the heart's structure and function, when determining whether patients with heart failure and a leaking heart valve are likely to benefit from valve repair, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.
Since the advent of effective antiretroviral therapy, human immunodeficiency virus infection has become more like a chronic illness.
More than 120 professionals from the field of health and other experts from thirty-three countries worldwide have taken part in the social awareness event of the EUDONORGAN project, an initiative directly launched by the European Parliament and led by the University of Barcelona, together with the Bosch i Gimpera Foundation and the DTI - TPM Foundation, located at the Barcelona Science Park.
Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.
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