Receptor News and Research

RSS

Discovery of receptor-free signaling reveals better targets for treating autoimmune diseases

Our understanding of how cells interact with each other has been driven for decades by the central concept of receptor-mediated signal transduction.

23 Sep 2026

New study highlights difficulty of detecting gastric ulcer pain in horses

A new study led by Australian veterinarians has exposed the challenge of identifying pain in horses with gastric ulcers and highlights an urgent need to better detect when horses are suffering.

23 Sep 2026

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

In a large UK Biobank study, higher levels of the chronic inflammation marker GlycA were associated with smaller heart chambers, thicker heart walls, impaired diastolic function, reduced stroke volume, and a 43% higher risk of major adverse cardiovascular events in the highest versus lowest GlycA group. Genetic susceptibility also modified the associations between environmental exposures, inflammation, and cardiovascular risk, while inflammatory proteins in the IL-1, TNF, and IL-6 pathways statistically mediated several of these associations.

23 Sep 2026

C-Path awards $1.7 million to advance five drug development projects

Critical Path Institute (C-Path) today announced that its Translational Therapeutics Accelerator has awarded $1,699,500 through five Bridging Research and Innovation in Drug Development Grants (BRIDGe).

22 Sep 2026

Retinal dopamine levels rise during inherited retinal degeneration

A new study by researchers at the University of Eastern Finland (UEF) reports changes in the dopamine system of the retina during inherited retinal degeneration.

22 Sep 2026

City of Hope develops adaptive plug-and-play CAR T technology to attack tumors

Researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the country, have developed a new "plug-and-play" technology that adds engineered molecules to chimeric antigen receptor (CAR) T cells after treatment, allowing scientists to better control the cells and redirect them to attack different types of cancer.

22 Sep 2026

Looking for GLP-1 advice online? Likes may tell you less than you think

Researchers assessed 128 videos about GLP-1 medications on Douyin and Bilibili and found that Bilibili videos scored higher on two measures of reliability and transparency. Longer videos received higher quality scores, while popularity did not consistently reflect information quality.

21 Sep 2026

SARS-CoV-2 protein ORF8 drives macrophage infection and lung inflammation

In the sickest COVID-19 patients, the SARS-CoV-2 virus doesn't just cause severe damage by directly infecting airway cells.

18 Sep 2026

NUS scientists harness magnetic pulses to reprogram immune cells to fight breast cancer

Researchers from the National University of Singapore (NUS) have demonstrated an innovative approach for targeted breast cancer therapy using pulsed electromagnetic fields (PEMFs).

18 Sep 2026

Sex-specific biological clocks reveal how aging differs across the body in women and men

Researchers developed 38 sex-specific biological aging clocks across 15 organ systems, finding differences between females and males in genetic architecture, molecular signatures, disease associations, and mortality patterns. Brain aging clocks were linked to progression from mild cognitive impairment to Alzheimer’s disease in both sexes and to sex-dependent cognitive trajectories among solanezumab-treated A4 participants, while the authors stressed that sex-pooled and sex-interaction models remain complementary approaches.

17 Sep 2026

Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see.

17 Sep 2026

Study identifies powerful inherited risk factor for lung cancer

A rare inherited mutation in the Epidermal Growth Factor Receptor (EGFR) gene is associated with a 25-fold increased risk of lung cancer, according to a study by investigators at Dana-Farber Cancer Institute and 23andMe Research Institute.

17 Sep 2026

Study identifies bile acid that helps reduce excess fat accumulation in the liver

Non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD), is a common condition that causes excess fat to build up in the liver, affecting about one-quarter of adults worldwide.

17 Sep 2026

High estrogen alters brain circuit causing temporary memory impairment during pregnancy

Many women usually say the same thing during pregnancy: they walk into a room and forget why, misplace their keys or struggle to follow a conversation.

17 Sep 2026

GLP-1 drugs and SGLT-2 inhibitors linked to slower kidney decline

The diabetes drugs glucagon-like peptide-1 (GLP-1) receptor agonists and sodium glucose cotransporter 2 (SGLT-2) inhibitor drugs may also help to slow decline in kidney function in people with type 2 diabetes and albuminuria (high protein levels in the urine), finds a large US study published by The BMJ today.

17 Sep 2026

Experts call for eating-disorder screening before GLP-1 treatment

An international multidisciplinary panel developed consensus-based recommendations for GLP-1 receptor agonist use in people with eating disorders, calling for screening, individualized monitoring, patient education, and further research into safety and potential therapeutic effects. The experts cautioned that current evidence remains limited and inconsistent, particularly outside binge eating disorder, and identified major gaps in understanding the risk of new or recurrent eating disorders during treatment.

16 Sep 2026

Shatavari may affect more than hormones, and the gut could help explain why

A review in Nutrients examined how bioactive compounds in Asparagus racemosus (Shatavari) may influence cognitive health through the microbiota-gut-brain axis, estrogen-related signaling, neuroinflammation, oxidative stress, and neurotransmitter regulation. Evidence from computational, cellular, animal, and limited human studies suggests several plausible biological pathways, but key questions remain about bioavailability, brain exposure, dosing, and clinical efficacy.

16 Sep 2026

Receptor News and Research

Discovery of receptor-free signaling reveals better targets for treating autoimmune diseases

New study highlights difficulty of detecting gastric ulcer pain in horses

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

C-Path awards $1.7 million to advance five drug development projects

Retinal dopamine levels rise during inherited retinal degeneration

City of Hope develops adaptive plug-and-play CAR T technology to attack tumors

Looking for GLP-1 advice online? Likes may tell you less than you think

SARS-CoV-2 protein ORF8 drives macrophage infection and lung inflammation

NUS scientists harness magnetic pulses to reprogram immune cells to fight breast cancer

Sex-specific biological clocks reveal how aging differs across the body in women and men

Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

Study identifies powerful inherited risk factor for lung cancer

Study identifies bile acid that helps reduce excess fat accumulation in the liver

High estrogen alters brain circuit causing temporary memory impairment during pregnancy

GLP-1 drugs and SGLT-2 inhibitors linked to slower kidney decline

Experts call for eating-disorder screening before GLP-1 treatment

Shatavari may affect more than hormones, and the gut could help explain why

Hedgehog coronaviruses reveal potential pathways for cross-species transmission

Study links missing brain protein to ADHD-like behaviors

Severe intestinal inflammation in preterm infants directly triggers brain damage

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News