Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

PET technique detects coronary disease much earlier than other leading imaging methods

Coronary artery disease (CAD) is one of the world's most prevalent and silent killers. Positron emission tomography (PET), which images miniscule abnormalities in cellular metabolism, can tip off clinicians about cardiac disasters waiting to happen- including sudden death from a heart attack-better than standard angiography, researchers revealed at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

12 Jun 2013

Abbott starts ABSORB Japan trial to evaluate Absorb BVS in patients with CAD

Abbott today announced that it has initiated the ABSORB Japan randomized controlled clinical trial to evaluate the Absorb Bioresorbable Vascular Scaffold in patients with coronary artery disease, the most common form of heart disease.

11 Jun 2013

Researchers discover way to stop atherosclerosis caused by diabetes

Researchers at Lund University in Sweden have discovered how to stop the destructive process that leads to cardiovascular disease in diabetic laboratory animals.

5 Jun 2013

Researchers report that two biomarkers appear to indicate risk for silent strokes

Two biomarkers widely being investigated as predictors of heart and vascular disease appear to indicate risk for "silent" strokes and other causes of mild brain damage that present no symptoms, report researchers from The Methodist Hospital and several other institutions in an upcoming issue of Stroke (now online).

5 Jun 2013

Study reveals how type 2 diabetes and CVD increase risk of cognitive decline

People suffering from type 2 diabetes and cardiovascular disease are at an increased risk of cognitive decline, according to a new study from Wake Forest Baptist Medical Center.

5 Jun 2013

Living in neighborhoods can make measurable difference in preventing obesity, study finds

Living in a neighborhood that supports a healthy lifestyle can make a measurable difference in preventing obesity, according to a longitudinal study recently published in the journal Obesity.

5 Jun 2013

Four lifestyle behaviors protect against coronary heart disease, say researchers

A large, multi-center study led by Johns Hopkins researchers has found a significant link between lifestyle factors and heart health, adding even more evidence in support of regular exercise, eating a Mediterranean-style diet, keeping a normal weight and, most importantly, not smoking.

3 Jun 2013

Synageva BioPharma presents data on cholesteryl ester storage disease at NLA annual meeting

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare diseases, announced three poster presentations at the National Lipid Association annual meeting held in Las Vegas, Nevada, May 30- June 2, 2013, as well as a Synageva-sponsored satellite symposium held on Friday, May 31, 2013.

1 Jun 2013

Discarded neutrophils release stem cells from bone marrow into bloodstream

CNIC researchers have discovered that the daily clearance of neutrophils from the body stimulates the release of hematopoietic stem cells from the bone marrow into the bloodstream, according to a report published today in the journal Cell.

24 May 2013

Study: Air and noise pollution may increase risk of cardiovascular disease

Both fine-particle air pollution and noise pollution may increase a person's risk of developing cardiovascular disease, according to German researchers who have conducted a large population study, in which both factors were considered simultaneously.

21 May 2013

Lund University researchers map significance of heredity for atherosclerotic disease

Researchers at Lund University in Sweden have mapped the significance of heredity for common forms of atherosclerotic disease. No studies have previously examined whether different forms of the disease share heredity.

21 May 2013

FDA designates Synageva's sebelipase alfa as Breakthrough Therapy for early onset LAL Deficiency

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare diseases, today announced that the U.S. Food and Drug Administration granted Breakthrough Therapy designation to sebelipase alfa for the treatment of early onset lysosomal acid lipase deficiency, also known as Wolman disease.

20 May 2013

Researchers examine new zinc-based bioabsorbable stents

In 2012, more than 3 million people had stents inserted in their coronary arteries. These tiny mesh tubes prop open blood vessels healing from procedures like a balloon angioplasty, which widens arteries blocked by clots or plaque deposits. After about six months, most damaged arteries are healed and stay open on their own. The stent, however, is there for a lifetime.

20 May 2013

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body.

17 May 2013

Breathing motor vehicle emissions triggers change in HDL cholesterol

Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.

16 May 2013

Study suggests that a blood protein contributes to early development of atherosclerosis

It's on Saturday that the Journal of the American Heart Association published the conclusive results from a study directed by Dr. Éric Thorin of the Montreal Heart Institute (MHI), which suggests for the first time that a blood protein contributes to the early development of atherosclerosis.

14 May 2013

Synageva BioPharma reports study results of sebelipase alfa in adults with late onset LAL Deficiency

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare diseases, today reported 12-month results from an ongoing extension study with sebelipase alfa in adults with late onset Lysosomal Acid Lipase Deficiency.

9 May 2013

New therapeutic targets for reducing heart disease in people with type 1 diabetes

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks an inflammatory process that fuels the buildup of artery-clogging plaque.

8 May 2013

Increased accumulation of coronary artery calcium leads to heart attack risk

Patients with increasing accumulations of coronary artery calcium were more than six times more likely to suffer from a heart attack or die from heart disease than patients who didn't have increasing accumulations, according to a recent study published in the Journal of the American College of Cardiology.

3 May 2013

Gene study may uncover regulatory network that influences development of cardiovascular disease

University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.

30 Apr 2013

Atherosclerosis News and Research

Further Reading

PET technique detects coronary disease much earlier than other leading imaging methods

Abbott starts ABSORB Japan trial to evaluate Absorb BVS in patients with CAD

Researchers discover way to stop atherosclerosis caused by diabetes

Researchers report that two biomarkers appear to indicate risk for silent strokes

Study reveals how type 2 diabetes and CVD increase risk of cognitive decline

Living in neighborhoods can make measurable difference in preventing obesity, study finds

Four lifestyle behaviors protect against coronary heart disease, say researchers

Synageva BioPharma presents data on cholesteryl ester storage disease at NLA annual meeting

Discarded neutrophils release stem cells from bone marrow into bloodstream

Study: Air and noise pollution may increase risk of cardiovascular disease

Lund University researchers map significance of heredity for atherosclerotic disease

FDA designates Synageva's sebelipase alfa as Breakthrough Therapy for early onset LAL Deficiency

Researchers examine new zinc-based bioabsorbable stents

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

Breathing motor vehicle emissions triggers change in HDL cholesterol

Study suggests that a blood protein contributes to early development of atherosclerosis

Synageva BioPharma reports study results of sebelipase alfa in adults with late onset LAL Deficiency

New therapeutic targets for reducing heart disease in people with type 1 diabetes

Increased accumulation of coronary artery calcium leads to heart attack risk

Gene study may uncover regulatory network that influences development of cardiovascular disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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