Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Researchers use AI platform to identify best combination of available therapies against COVID-19.

A team of researchers from the National University of Singapore (NUS) has utilized a ground-breaking artificial intelligence (AI) platform to derive an optimal combination of available therapies against SARS-CoV-2, the cause of COVID-19.

11 Dec 2020

MUSC cancer researcher named as a 2020 fellow of National Academy of Innovators

In recognition of her spirit of innovation and the lasting impact of her work on cancer patients, MUSC Hollings Cancer Center researcher Nancy Klauber-DeMore, M.D., has been named as a 2020 fellow of the National Academy of Innovators, the organization announced Dec. 8.

10 Dec 2020

Using AI to find optimal combination of available therapies against SARS-CoV-2

A team of researchers from the National University of Singapore has utilized a ground-breaking artificial intelligence (AI) platform to derive an optimal combination of available therapies against SARS-CoV-2, the cause of COVID-19.

10 Dec 2020

Synthetic biology and machine-learning can speed up maturation of lab-grown organ

Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine-learning algorithm to create human liver organoids with blood- and bile-handling systems. When implanted into mice with failing livers, the lab-grown replacement livers extended life.

8 Dec 2020

Study reveals rare spawning behavior of shallow-water fish

A new study provides the first detailed documentation of a shallow-water fish diving 450 feet deep to spawn. Uncovering this very rare spawning behavior in bonefish (Albula vulpes) is unprecedented.

8 Dec 2020

Evolution of the SARS-CoV-2 proteome in 3D during the first six months of the COVID-19 pandemic

In a recent study, researchers report how the SARS-CoV-2 proteome in 3D has evolved during the first six months of the COVID-19 pandemic.

7 Dec 2020

Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Researchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's disease (AD) that could lead to therapies focused on treating the neurodegenerative condition early in its progression.

7 Dec 2020

ATCC introduces new product segment with launch of SARS-CoV-2 external control kit

ATCC today announced the introduction of its new SARS-CoV-2 External Control Kit for clinical laboratories and test manufacturers.

From American Type Culture Collection (ATCC) 4 Dec 2020

New initiative seeks to accelerate global collaborative research on COVID-19

During the COVID-19 pandemic, health care professionals and researchers have been confined mostly to using local and national datasets to study the impact of comorbidities, pre-existing medication use, demographics and various interventions on disease course.

3 Dec 2020

Horizon Discovery licenses CHOSOURCE to Sanyou Biopharmaceuticals Co.

Horizon Discovery today announced that it has granted commercial licenses for its cGMP-compliant CHOSOURCE™ platform to Sanyou Biopharmaceuticals.

From Revvity 2 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

Machine learning model uses retinal scans to detect Alzheimer’s disease

A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer's disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study from Duke University.

30 Nov 2020

Biogelx Announces Formation of Scientific Advisory Board

Biogelx today announced the creation of its Scientific Advisory Board to provide scientific review and guidance to the company regarding development.

27 Nov 2020

Deep learning helps determine a woman’s risk of breast cancer

A new deep learning model could more accurately predict a woman’s risk of developing breast cancer than current risk assessment tools.

27 Nov 2020

‘Molecular clock’ blood test could help identify actively growing tumors in metastatic breast cancer

A blood test to watch breast cancer’s ‘molecular clock’ could help track the growth of multiple tumors around the body and monitor how they are responding to treatment, new research suggests.

27 Nov 2020

Fruit fly study reveals the effects of microgravity on the heart

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that fruit flies that spent several weeks on the International Space Station (ISS)—about half of their lives—experienced profound structural and biochemical changes to their hearts.

25 Nov 2020