Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

ESMO Congress 2024 to unveil future-focused cancer treatments

The ESMO Congress 2024 will hold a press conference to introduce and discuss the "Eyes to the Future" Presidential Symposium 3, that will be presenting prominent approaches that have the potential to become increasingly effective and influential components of cancer treatment in the (near) future.

16 Sep 2024

Combination treatment improves symptoms of agitated delirium in end-of-life cancer patients

Treatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

16 Sep 2024

Combination immunotherapy yields 10-year survival for metastatic melanoma patients

Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new report from Weill Cornell Medicine and Dana-Farber Cancer Center investigators and their colleagues.

16 Sep 2024

High-dose vitamin D3 cannot be recommended as treatment for metastatic colon cancer

A double-blind randomized phase 3 clinical trial led by Dana-Farber Cancer Institute researchers and conducted across several hundred cancer centers in the U.S. tested the addition of high-dose vitamin D3 to standard treatment for patients with untreated metastatic colorectal cancer.

16 Sep 2024

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

16 Sep 2024

Antibody-drug conjugate shows promise in treating ovarian and endometrial cancers

Studies reported at ESMO 2024 reveal new groups of women with early-stage endometrial and cervical cancers who gain clinically meaningful benefit from adding immunotherapy to current standard treatments, while a first-in-human study found 'promising' antitumor activity with a novel antibody drug conjugate (ADC) targeting the protein claudin 6 in heavily pretreated patients with ovarian and endometrial cancers.

14 Sep 2024

New cancer drug shows encouraging results in Phase I/II trial

The antibody-drug conjugate (ADC) puxitatug samrotecan (AZD8205) demonstrated a manageable safety profile consistent with similar ADCs and initial efficacy in heavily pretreated patients with advanced or metastatic solid tumors, according to interim data shared today at the 2024 European Society for Medical Oncology (ESMO) Congress by researchers from The University of Texas MD Anderson Cancer Center.

14 Sep 2024

New drug shows strong activity against brain metastases in HER2-positive breast cancer

A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer.

13 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

Trial finds no benefit of adding nivolumab to tivozanib for advanced kidney cancer

In an international multicenter randomized phase 3 clinical trial led by Dana-Farber Cancer Institute, researchers tested the addition of the immune checkpoint inhibitor (ICI) nivolumab to treatment with tivozanib for patients with advanced clear cell renal cell carcinoma, a form of kidney cancer.

13 Sep 2024

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

A new editorial was recently published in Oncotarget's Volume 15, on July 10, 2024, entitled, "The advances in targeting CD47/SIRPα "do not eat me" axis and their ongoing challenges as an anticancer therapy."

13 Sep 2024

$Hypofractionation proven safer and more convenient for breast cancer treatment$

Hypofractionation proven safer and more convenient for breast cancer treatment

Giving higher doses per fraction of radiation therapy over a shorter time after breast cancer surgery significantly reduces the risk of side effects and improves quality of life compared with a conventional schedule, finds a study published by The BMJ today.

13 Sep 2024

Cancer cases in the US continued to be underdiagnosed during the second year of the COVID-19 pandemic

Researchers examine how the COVID-19 pandemic affected cancer diagnosis rates between 2021 and 2020.

13 Sep 2024

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

12 Sep 2024

Nucleophagy identified as key DNA repair mechanism in cancer treatments

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is particularly relevant for patients undergoing colorectal cancer treatments.

12 Sep 2024

Five key factors identified for predicting immunotherapy response in cancer patients

Immunotherapy has transformed cancer treatment in recent years by enabling the immune system to attack tumor cells.

12 Sep 2024

NCCN expands cancer guidelines library with Spanish translations and more languages

The National Comprehensive Cancer Network;an alliance of leading cancer centers - and the NCCN Foundation proudly announce plans to make every book in the library of NCCN Guidelines for Patients available in Spanish; with select editions available in additional languages as well.

12 Sep 2024

Duffy-null phenotype may lead to unfair exclusion from cancer drug trials

Many clinical trials of new cancer drugs may be inappropriately excluding some people with "Duffy-null phenotype," a trait found predominantly in people of African or Middle Eastern descent, researchers at Dana-Farber Cancer Institute and Queen Mary University of London report in a new study.

12 Sep 2024

Long radiotherapy course shows better organ preservation in rectal cancer

The COVID-19 pandemic has enabled researchers to show that a long course of radiotherapy given before surgery may be a better treatment for avoiding surgery, preserving the rectum and anus, and preventing regrowth of the primary tumor than a short course of radiotherapy for patients with rectal cancer – a type of bowel cancer.

11 Sep 2024

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

The c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an acceptable safety profile in patients of Asian race with c-Met protein-overexpressing, epidermal growth factor receptor (EGFR) wildtype (WT), locally advanced/metastatic nonsquamous non-small cell lung cancer (NSCLC), according to research presented today at the International Association for the Study of Lung Cancer's 2024 World Conference on Lung Cancer.

11 Sep 2024

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Oncology News and Research

Further Reading

ESMO Congress 2024 to unveil future-focused cancer treatments

Combination treatment improves symptoms of agitated delirium in end-of-life cancer patients

Combination immunotherapy yields 10-year survival for metastatic melanoma patients

High-dose vitamin D3 cannot be recommended as treatment for metastatic colon cancer

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

Antibody-drug conjugate shows promise in treating ovarian and endometrial cancers

New cancer drug shows encouraging results in Phase I/II trial

New drug shows strong activity against brain metastases in HER2-positive breast cancer

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Trial finds no benefit of adding nivolumab to tivozanib for advanced kidney cancer

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

Hypofractionation proven safer and more convenient for breast cancer treatment

Cancer cases in the US continued to be underdiagnosed during the second year of the COVID-19 pandemic

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

Nucleophagy identified as key DNA repair mechanism in cancer treatments

Five key factors identified for predicting immunotherapy response in cancer patients

NCCN expands cancer guidelines library with Spanish translations and more languages

Duffy-null phenotype may lead to unfair exclusion from cancer drug trials

Long radiotherapy course shows better organ preservation in rectal cancer

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

Your guide to microplate readers for cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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