Immune System News and Research

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Common test may overestimate exposure to mercury vapor from dental amalgams

A common test used to determine mercury exposure from dental amalgam fillings may significantly overestimate the amount of the toxic metal released from fillings, according to University of Michigan researchers.

21 Mar 2013

Phase II trial results of OHR/AVR118 in patients with cancer cachexia announced

Ohr Pharmaceutical, a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, today announced the results of a Phase II trial to evaluate the effects of OHR/AVR118 in advanced cancer patients with cachexia. Cancer cachexia is the complex, multi-symptom syndrome seen in late-stage cancer patients, characterized by anorexia and unintended loss of appetite, progressive and continual weight loss, accompanied by generalized host tissue wasting, skeletal muscle atrophy, immune and metabolic dysfunction, and a greatly diminished quality of life.

21 Mar 2013

Investigators examine effectiveness of probiotics for cancer treatment

One may not think of probiotics -- like those found in yogurt that promote good digestive health -- as a weapon used in the fight against cancer. But that is the focus of investigators at The Cancer Institute of New Jersey, who are examining the effectiveness of probiotics as they relate to the outcomes of bone marrow transplant for patients with blood cancers.

21 Mar 2013

Researchers develop promising drug candidate to treat psoriasis

Ben-Gurion University of the Negev researchers, in collaboration with Teva Pharmaceutical Industries Ltd., have developed a promising drug candidate to treat psoriasis.

21 Mar 2013

Genetically modified tomatoes mimic actions of good cholesterol

UCLA researchers have genetically engineered tomatoes to produce a peptide that mimics the actions of good cholesterol when consumed.

20 Mar 2013

Hepatitis C and HIV co-infection treatment: an interview with Prof Boecher, Boehringer Ingelheim

Chronic hepatitis C infection is one of the most frequent chronic infectious diseases worldwide. The WHO estimates that 150 million people worldwide are chronically infected with the hepatitis C virus (HCV).

20 Mar 2013

Study: Health of critically ill newborns is endangered by insufficient nurse staffing

A new study reveals that the health of critically ill newborns is endangered by insufficient nurse staffing. The national study finds that very few neonatal intensive care units (NICUs) provide sufficient numbers of nurses to meet guidelines and that the most vulnerable babies are also the most understaffed.

20 Mar 2013

Nanomedicines prevent tissue damage associated with atherosclerosis, other chronic diseases

Doses of medicine 100,000 times smaller than the diameter of a human hair prevent the tissue damage associated with atherosclerosis and other chronic diseases in mice.

20 Mar 2013

St. Jude Children's Research Hospital receives patent for genetically modified human immune cells for caner therapy

The United States Patent and Trademark Office today awarded St. Jude Children's Research Hospital U.S. patent number 8,399,645 for St. Jude's invention of compositions for genetically modifying human immune cells so they can destroy some of the most common forms of cancer in children and adults.

20 Mar 2013

Research findings could lead to development of new drugs for gout treatment

Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout.

20 Mar 2013

Protein derived from Pacific cod may inhibit prostate cancer, researchers say

Researchers at the University of Maryland School of Medicine have identified a peptide, or protein, derived from Pacific cod that may inhibit prostate cancer and possibly other cancers from spreading, according to preclinical research published online in the Proceedings of the National Academy of Sciences.

20 Mar 2013

Scientists open door to significantly improved treatments for multiple sclerosis

A team of basic and clinical scientists led by the University of Montreal Hospital* Research Centre's Dr. Nathalie Arbour has opened the door to significantly improved treatments for the symptoms of Multiple Sclerosis.

20 Mar 2013

Research reveals method to produce retinal cells from regenerative human stem cells

Research led by a biology professor in the School of Science at Indiana University-Purdue University Indianapolis has uncovered a method to produce retinal cells from regenerative human stem cells without the use of animal products, proteins or other foreign substances, which historically have limited the application of stem cells to treat disease and other human developmental disorders.

20 Mar 2013

New study may help develop targeted therapies for controlling tissue destruction

Stroke, heart attacks and numerous other common disorders result in a massive destruction of cells and tissues called necrosis. It's a violent event: As each cell dies, its membrane ruptures, releasing substances that trigger inflammation, which in turn can cause more cellular necrosis.

19 Mar 2013

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Researchers find white blood cells produce and eliminate RBCs

Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages - white blood cells that play a key role in the immune response - also help to both produce and eliminate the body's red blood cells (RBCs).

18 Mar 2013

Cytomegalovirus employs a novel trick to hide from immune detection

A virus that most people have probably never heard of, yet most of us carry, is the number 1 infectious cause of congenital birth defects. One in 750 children are born with, or develop, permanent disabilities such as hearing loss or brain damage as a result of CMV (cytomegalovirus) infection in the womb.

17 Mar 2013

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's syndrome (HS), according to results of a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

17 Mar 2013

Study shows promising benefit of combination therapy in CRPC patients

Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

16 Mar 2013

Small percentage of adults who receive rapid HIV treatment following infection might achieve 'functional cure,' French researchers say

"Rapid treatment after HIV infection may be enough to 'functionally cure' about a 10th of those diagnosed early, say researchers in France," who "have been analyzing 14 people who stopped therapy, but have since shown no signs of the virus resurging," BBC News reports (Gallagher, 3/15).

16 Mar 2013

Immune System News and Research

Common test may overestimate exposure to mercury vapor from dental amalgams

Phase II trial results of OHR/AVR118 in patients with cancer cachexia announced

Investigators examine effectiveness of probiotics for cancer treatment

Researchers develop promising drug candidate to treat psoriasis

Genetically modified tomatoes mimic actions of good cholesterol

Hepatitis C and HIV co-infection treatment: an interview with Prof Boecher, Boehringer Ingelheim

Study: Health of critically ill newborns is endangered by insufficient nurse staffing

Nanomedicines prevent tissue damage associated with atherosclerosis, other chronic diseases

St. Jude Children's Research Hospital receives patent for genetically modified human immune cells for caner therapy

Research findings could lead to development of new drugs for gout treatment

Protein derived from Pacific cod may inhibit prostate cancer, researchers say

Scientists open door to significantly improved treatments for multiple sclerosis

Research reveals method to produce retinal cells from regenerative human stem cells

New study may help develop targeted therapies for controlling tissue destruction

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Researchers find white blood cells produce and eliminate RBCs

Cytomegalovirus employs a novel trick to hide from immune detection

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

Study shows promising benefit of combination therapy in CRPC patients

Small percentage of adults who receive rapid HIV treatment following infection might achieve 'functional cure,' French researchers say

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