Immune System News and Research

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Study: Flagellin plays a critical role in regulating host innate defences against UTIs

A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs).

15 Mar 2013

Previously unknown cell discovered in the urethra of mice

A recent study conducted by a group of German scientists revealed the presence of a previously unknown cell in the urethra of mice. These chemosensory cholinergic brush cells are in close contact to sensory neurons that express cholinergic receptors.

15 Mar 2013

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific for proteins on the outside of the virus, specifically the hemagglutinin protein.

15 Mar 2013

Probiotics help stress-associated gastrointestinal disorders, study says

For those with irritable bowel syndrome who wonder if stress aggravates their intestinal disorder, a new University of Michigan Health System study shows it's not all in their head.

15 Mar 2013

Researchers: Acupuncture can reduce stress hormone response in animal model of chronic stress

While acupuncture is used widely to treat chronic stress, the mechanism of action leading to reported health benefits are not understood. In a series of studies at Georgetown University Medical Center, researchers are demonstrating how acupuncture can significantly reduce the stress hormone response in an animal model of chronic stress.

15 Mar 2013

Scientists to create new human monoclonal antibody targeting protein associated with cancer

Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer are buried inside cancer cells.

14 Mar 2013

Research finding aids efforts toward cytomegalovirus vaccine

A virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero development, 1 in 750 children are born with or develop permanent disabilities such as hearing loss or brain damage.

14 Mar 2013

UCSF study on T-cell behavior sheds light on how vaccines work

The immune system's T cells, while coordinating responses to diseases and vaccines, act like honey bees sharing information about the best honey sources, according to a new study by scientists at UC San Francisco.

14 Mar 2013

More frequent HIV testing would be cost-effective for high- and low-risk groups, researchers report

Early HIV treatment can save lives as well as have profound prevention benefits. But those infected with the virus first must be identified before they can be helped.

14 Mar 2013

Study: Dietary deficiency of mineral selenium likely to be endemic among Malawi population

Enriching crops by adding a naturally-occurring soil mineral to fertilisers could potentially help to reduce disease and premature death in the African country of Malawi, researchers have said.

14 Mar 2013

Researchers study how skin microbiome gets transmitted between players using roller derby

The human skin is home to countless microorganisms that we can't see, but these microbes help define who we are. Our invisible passengers - known as the skin microbiome - contribute to our health in numerous ways including educating our immune system, protecting us from pathogens, and mediating skin disorders.

14 Mar 2013

Studies show local chemotherapy more effective in reducing tumor growth than regular chemotherapy

Reducing the growth of a tumor by localized delivery of cancer medication can be achieved by using a combination of ultrasound, temperature-sensitive nanoparticles and MRI.

14 Mar 2013

Immune system B cells play crucial role in defence of pathogens

Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy.

13 Mar 2013

MGH investigators identify new disease that causes widespread chronic pain in children

Massachusetts General Hospital (MGH) investigators have described what may be a newly identified disease that appears to explain some cases of widespread chronic pain and other symptoms in children and young adults.

13 Mar 2013

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms.

13 Mar 2013

Pneumococcal vaccine pre-clinical development supported by £0.2 million award from Biomedical Catalyst

ImmBio (Immunobiology Ltd), a biopharmaceutical company developing innovative vaccines against serious infectious diseases, today announced that the UK government-backed Biomedical Catalyst has awarded the company approximately £0.2 million ($0.3 million) to support pre-clinical development of its pneumococcal vaccine, PnuBioVax™, which targets a wide range of strains of the bacteria.

12 Mar 2013

Many challenges exist to delivering proven interventions for preventing pediatric HIV infections

Last week's "scientific report on the 'functional cure' of a HIV-infected infant has set the world's media ablaze with discussion and speculation," Randal Kuhn, director of the Global Health Affairs Program at the University of Denver's Josef Korbel School of International Studies, and Benjamin Young, chief medical officer of the International Association of Providers of AIDS Care, write in a GlobalPost opinion piece.

12 Mar 2013

Study: No increase in mortality with well-controlled HIV

For HIV-infected patients whose disease is well-controlled by modern treatment, the risk of death is not significantly higher than in the general population, according to a study published in AIDS, official journal of the International AIDS Society. AIDS is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

12 Mar 2013

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

Influenza or flu for short is caused by a family of viruses, which can be called influenza A or influenza B. Influenza A viruses are found in humans, animals – like swine and horses- and mostly aquatic birds. Influenza B is only found in humans.

11 Mar 2013

Cell fusion studies at Johns Hopkins could lead to improved treatments for muscular dystrophy

Researchers at Johns Hopkins have established a high-efficiency cell-cell fusion system, providing a new model to study how fusion works. The scientists showed that fusion between two cells is not equal and mutual as some assumed, but, rather, is initiated and driven by one of the fusion partners. The discovery, they say, could lead to improved treatments for muscular dystrophy, since muscle regeneration relies on cell fusion to make muscle fibers that contain hundreds or even thousands of nuclei.

8 Mar 2013

Immune System News and Research

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

Previously unknown cell discovered in the urethra of mice

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Probiotics help stress-associated gastrointestinal disorders, study says

Researchers: Acupuncture can reduce stress hormone response in animal model of chronic stress

Scientists to create new human monoclonal antibody targeting protein associated with cancer

Research finding aids efforts toward cytomegalovirus vaccine

UCSF study on T-cell behavior sheds light on how vaccines work

More frequent HIV testing would be cost-effective for high- and low-risk groups, researchers report

Study: Dietary deficiency of mineral selenium likely to be endemic among Malawi population

Researchers study how skin microbiome gets transmitted between players using roller derby

Studies show local chemotherapy more effective in reducing tumor growth than regular chemotherapy

Immune system B cells play crucial role in defence of pathogens

MGH investigators identify new disease that causes widespread chronic pain in children

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

Pneumococcal vaccine pre-clinical development supported by £0.2 million award from Biomedical Catalyst

Many challenges exist to delivering proven interventions for preventing pediatric HIV infections

Study: No increase in mortality with well-controlled HIV

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

Cell fusion studies at Johns Hopkins could lead to improved treatments for muscular dystrophy

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