Immune System News and Research

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Clinical Research Forum selects sickle cell project among 'Top 10' clinical research achievements of 2012

Pioneering research led by Johns Hopkins scientists on the use of partially matched bone marrow transplants to wipe out sickle cell disease has been selected as one of the Top 10 Clinical Research Achievements of 2012 by the Clinical Research Forum.

22 Apr 2013

Aurigene and Endo’s collaborative efforts yield novel drug candidates

Aurigene and Endo entered into collaboration in 2009, for multiple integrated drug discovery programs in the areas of Inflammation and Oncology.

22 Apr 2013

Edible malarial vaccine may work against other viral and bacterial infections

Can scientists rid malaria from the Third World by simply feeding algae genetically engineered with a vaccine? That's the question biologists at UC San Diego sought to answer after they demonstrated last May that algae can be engineered to produce a vaccine that blocks malaria transmission.

22 Apr 2013

Genetic study defines link between primary sclerosing cholangitis and other autoimmune diseases

Researchers have newly associated nine genetic regions with a rare autoimmune disease of the liver known as primary sclerosing cholangitis (PSC). This brings the total number of genetic regions associated with the disease to 16.

22 Apr 2013

Researchers decipher the underlying mechanism of antiviral drug

A long-forgotten candidate for antiviral therapy is undergoing a renaissance: Since the 1970s, the small molecule CMA has been considered a potent agent against viral infections, yet it was never approved for clinical use.

22 Apr 2013

Study: Use of anti-TNF therapies in RA patients does not increase risk of herpes zoster

Patients with rheumatoid arthritis (RA) who initiated use of anti-tumor necrosis factor therapies were not at a higher risk of developing herpes zoster (shingles), compared with patients who initiated nonbiologic treatment regimens, according to research from the University of Alabama at Birmingham (UAB) and the Oregon Health and Science University. The findings appeared in the March 6, 2013, issue of the Journal of the American Medical Association (JAMA).

22 Apr 2013

FAP cells help in repairing injured muscles

UC San Francisco scientists have discovered that muscle repair requires the action of two types of cells better known for causing inflammation and forming fat.

20 Apr 2013

Circumcision lowers bacterial load, possibly allowing for HIV infection risk reduction, researchers say

"Circumcision reduces a man's risk of acquiring and transmitting HIV and other sexually transmitted diseases, and now researchers have found a possible explanation: the procedure reduces the quantity and diversity of bacteria at the head of the penis," the New York Times' "Well" blog reports (Bakalar, 4/18).

20 Apr 2013

BIIR researchers report results of comparative study of molecular immune responses to influenza and pneumococcal vaccines

In a manuscript published today in Immunity, scientists at the Baylor Institute for Immunology Research (BIIR) and the Benaroya Research Institute at Virginia Mason report the results of a comparative study of the molecular immune responses to influenza and pneumococcal vaccines.

19 Apr 2013

SCCA pioneers new transplant procedures to reduce need for matching bone marrow donors

Patients from ethnic minority and mixed-racial backgrounds are less likely to receive a lifesaving bone marrow transplant than Caucasian patients with the same disease due to lack of matching donors, according to the National Marrow Donor Program.

19 Apr 2013

GBM brain cancer patient treated with DCVax-L celebrates 10th anniversary of cancer-free survival

Northwest Biotherapeutics, a biotechnology company developing DCVax personalized immune therapies for solid tumor cancers, announced today that Brad Silver, an All American swimming and water polo athlete who was diagnosed with Glioblastoma multiforme brain cancer in late 2002, and was treated with DCVax-L in March of 2003, just celebrated the 10th anniversary of his continued cancer-free survival.

19 Apr 2013

SynCon universal H1N1 influenza vaccine generates protective antibody levels in phase 1 study

Inovio Pharmaceuticals, Inc. announced today that its SynCon universal H1N1 influenza vaccine generated protective antibody levels comparable to a current FDA-approved seasonal influenza vaccine against a currently circulating influenza strain.

19 Apr 2013

Researcher explores new way to deliver therapy to brain metastases from primary breast cancer

An Indiana University School of Medicine breast cancer surgeon is pursuing research that will utilize glass, gold, nanotechnology and Greek mythology hoping to vanquish breast cancer that has metastasized to the brain.

19 Apr 2013

Researchers propose strategies for improving the anti-cancer effects of interferon

Interferons have antitumor activity and have been used to treat a variety of malignancies, including colorectal and ovarian cancers.

18 Apr 2013

New assays are effective in managing patients with influenza virus infection

Over 40,000 people die each year in the United States from influenza-related diseases. In patients whose immune systems are compromised, antiviral therapy may be life-saving, but it needs to be initiated quickly. It is therefore crucial to diagnose and type the influenza rapidly.

18 Apr 2013

Two abstracts related to Advaxis' ADXS-HPV selected for poster presentation at ASCO meeting

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that two abstracts related to ADXS-HPV (ADXS11-001), the Company's lead clinical stage product candidate, have been selected for poster presentation at the 2013 American Society of Clinical Oncology Annual Meeting in Chicago, IL, from May 31 - June 4, 2013, at the McCormick Place Convention Center.

18 Apr 2013

CRISPR helps some bacteria evade mammalian immune system

CRISPR, a system of genes that bacteria use to defend themselves against viruses, has been found to be involved in helping some bacteria evade the mammalian immune system.

18 Apr 2013

Animal medication studies may lead way in discovering new drugs to relieve human suffering

It's been known for decades that animals such as chimpanzees seek out medicinal herbs to treat their diseases. But in recent years, the list of animal pharmacists has grown much longer, and it now appears that the practice of animal self-medication is a lot more widespread than previously thought, according to a University of Michigan ecologist and his colleagues.

18 Apr 2013

Findings hold promise for development of therapies to fight different viral infections

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells.

18 Apr 2013

IDRI, Medicago announce positive Phase I clinical trial results for avian flu pandemic vaccine

IDRI, a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today reported positive interim results from a Phase I clinical trial for an H5N1 Avian Influenza VLP vaccine candidate.

18 Apr 2013

Immune System News and Research

Clinical Research Forum selects sickle cell project among 'Top 10' clinical research achievements of 2012

Aurigene and Endo’s collaborative efforts yield novel drug candidates

Edible malarial vaccine may work against other viral and bacterial infections

Genetic study defines link between primary sclerosing cholangitis and other autoimmune diseases

Researchers decipher the underlying mechanism of antiviral drug

Study: Use of anti-TNF therapies in RA patients does not increase risk of herpes zoster

FAP cells help in repairing injured muscles

Circumcision lowers bacterial load, possibly allowing for HIV infection risk reduction, researchers say

BIIR researchers report results of comparative study of molecular immune responses to influenza and pneumococcal vaccines

SCCA pioneers new transplant procedures to reduce need for matching bone marrow donors

GBM brain cancer patient treated with DCVax-L celebrates 10th anniversary of cancer-free survival

SynCon universal H1N1 influenza vaccine generates protective antibody levels in phase 1 study

Researcher explores new way to deliver therapy to brain metastases from primary breast cancer

Researchers propose strategies for improving the anti-cancer effects of interferon

New assays are effective in managing patients with influenza virus infection

Two abstracts related to Advaxis' ADXS-HPV selected for poster presentation at ASCO meeting

CRISPR helps some bacteria evade mammalian immune system

Animal medication studies may lead way in discovering new drugs to relieve human suffering

Findings hold promise for development of therapies to fight different viral infections

IDRI, Medicago announce positive Phase I clinical trial results for avian flu pandemic vaccine

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