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CRISPR-scanning could lead to more effective treatments for cancer

11,000 people are predicted to die from acute myeloid leukemia in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to prevent blood cells from replicating again and again and again, growing tumors.

16 Apr 2019

Spatial orgnization of the genome can be altered using small molecules

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs.

16 Apr 2019

New catalog of DNA mutation 'fingerprints' could help doctors pinpoint cancer culprits

Scientists in Cambridge and London have developed a catalog of DNA mutation 'fingerprints' that could help doctors pinpoint the environmental culprit responsible for a patient's tumor - including showing some of the fingerprints left in lung tumors by specific chemicals found in tobacco smoke.

16 Apr 2019

Cannabis users could be more tolerant to anesthesia agents

Researchers from Colorado have found that people who regularly use cannabis are more likely to be tolerant to anesthetic agents and may require higher doses to achieve same effects as non users.

15 Apr 2019

Researchers uncover cellular resistance mechanisms to BRAF inhibitors in melanoma

Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, due to the development of drug resistance and tumor recurrence.

15 Apr 2019

Mulvaney: Trump brought down drug prices for the first time in 50 years

President Donald Trump announced last month that the GOP will become “the party of health care,” and news reports suggest he intends to make it a top issue in his reelection campaign.

15 Apr 2019

UTA scientist receives $1.17 million grant for cancer research

A scientist's research at The University of Texas at Arlington could lead to more effective, targeted treatment of cancer cells--adding to the University's diverse array of projects focused on advancing health and the human condition.

15 Apr 2019

Neuronal mechanisms underlying formation and retrieval of cocaine-associated memories

The environmental context in which addicts experience the rewarding effects of cocaine can readily elicit cocaine-associated memories. These memories persist long after abstinence and trigger cocaine-craving and consumption.

15 Apr 2019

Restoring function of 'misregulated' cancer-fighting genes

Working with human colon cancer cells and mice, researchers led by experts at the Johns Hopkins Kimmel Cancer Center say they have successfully blocked the activity of portions of a protein known as UHRF1 and restored the function of hundreds of cancer-fighting genes that became "misregulated" by the disease.

15 Apr 2019

Using slime mold to produce accessible biosensors

An EU-funded project is using slime mold to produce accessible sensing devices with a wide range of applications, including environmental monitoring and health - helping European industry become more competitive in the growing biosensor device market.

15 Apr 2019

IMI launches new project that focuses on development of new biomarkers

The University of Zurich coordinates a worldwide research project that focuses on the development of new biomarkers.

15 Apr 2019

Cancer cells use tactics to avoid being recognised by immunotherapy agents

Researchers have found that bowel cancer cells have a mechanism by which they can switch off some key molecules on their surfaces and thus escape being recognised and killed by the immunotherapy agents.

15 Apr 2019

Study finds ‘superbug’ in hands or nostrils of patients staying in the hospital

For decades, hospitals have worked to get doctors, nurses and others to wash their hands and prevent the spread of germs.

15 Apr 2019

Novo Biosciences achieves major milestones in its new drug to treat heart disease and DMD

Novo Biosciences Inc., has achieved several major milestones in its mission of bringing its breakthrough drug candidate, trodusquemine, to market as a potential regenerative medicine treatment for heart disease and Duchenne muscular dystrophy.

15 Apr 2019

Hospital ICU patients with non-brain-related injuries may have undetected cognitive deficits

A new study led by Western University and Lawson Health Research Institute has found that most patients entering hospital intensive care units (ICU) for non-brain-related injuries or ailments also suffer from some level of related cognitive dysfunction that currently goes undetected in most cases.

12 Apr 2019

Discovery of biomarkers could lead to new, better treatment options for heart disease

Coronary heart disease is a leading cause of death worldwide, but identifying those at high risk remains difficult. EU-funded research has helped identify new biomarkers that will improve diagnosis and lead to new and better treatment options.

12 Apr 2019

Potential new therapeutic approach identified for neuroblastoma tumors

Research led by Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and identified a potential new therapeutic approach for the disease.

12 Apr 2019

FDA approves new treatment for adults with metastatic bladder cancer

The U.S. Food and Drug Administration today granted accelerated approval to Balversa (erdafitinib), a treatment for adult patients with locally advanced or metastatic bladder cancer that has a type of susceptible genetic alteration known as FGFR3 or FGFR2, and that has progressed during or following prior platinum-containing chemotherapy.

12 Apr 2019

Removing damaged mitochondria may relieve chronic inflammatory conditions

Researchers have discovered a potential new way to treat chronic inflammatory diseases, by eliminating damaged mitochondria before they trigger excessive inflammation.

12 Apr 2019

ACR praises Representatives Ruiz and Wenstrup for introducing bipartisan step therapy legislation

The American College of Rheumatology today praised Representative Raul Ruiz, MD (D-CA) and Representative Brad Wenstrup, MD (R-OH) for introducing the "Safe Step Act" (H.R. 2279). If enacted, H.R. 2279 would place reasonable parameters around the use of step therapy among employer-sponsored health plans.

12 Apr 2019