Drugs News and Research

RSS

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher Navin Varadarajan has published in Arthritis & Rheumatology journal a first-of-its-kind study - a comprehensive profile of B cells in rheumatoid arthritis.

12 Apr 2019

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. I

12 Apr 2019

Researchers discover unique approach to treat some chronic inflammatory diseases

Inflammation is a balanced physiological response -- the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases.

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

The two-hit model can lead to better understanding of heart failure

Nearly half of current hospital admissions for heart failure are caused by a type of the disease with no treatment options. Cardiology researchers at UT Southwestern Medical Center are changing that reality with a fresh approach, recently published in Nature.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

FDA issues safety labeling changes for female sexual dysfunction treatment

The U.S. Food and Drug Administration today issued a safety labeling change order to Sprout Pharmaceuticals for their drug, Addyi (flibanserin), that requires the company to revise important safety information that women and their health care professionals need to have when considering use of the drug.

12 Apr 2019

Rare gut condition is more predictable from individual's genetic makeup, study finds

Hirschsprung disease - a rare condition where the failure of gut nerves to develop before birth leads to impaired bowel contractions that prevent infants from passing stool - is more predictable from an individual's genetic makeup than previously envisioned.

11 Apr 2019

USC researchers report breakthrough to prevent osteonecrosis of the jaw

USC researchers and collaborators report a breakthrough to prevent damage to the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis.

11 Apr 2019

Prostate drugs linked to increased risk of developing type 2 diabetes

Researchers say patients should continue to take the drugs, which are commonly prescribed to older men, but warn they may need additional health checks.

11 Apr 2019

Scientists aim to minimize or eliminate hair loss during cancer treatment

SCIENTISTS at the University of Huddersfield aim to minimize or eliminate completely, the hair loss that is one of the most distressing side-effects of cancer treatment.

11 Apr 2019

Hundreds of new anti-cancer drug targets identified using CRISPR

A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells.

11 Apr 2019

Experimental drug may be twice as good at fighting vision loss as previously thought

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.

11 Apr 2019

Characterizing Small Molecules with NMR

In this interview, Marcel Lachenmann describes the importance of characterizing small molecules in the pharma, food and polymer industry and how NMR achieves this.

From Oxford Instruments - Life Sciences 11 Apr 2019

Biochemical switches could be triggered to treat pathology of IBM, ALS and FTD

St. Jude Children's Research Hospital scientists have found that the enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that kill muscle and brain cells.

11 Apr 2019

GARDP forms multi-actor partnerships to discover new antibiotics

Multi-actor partnership tests natural products and compound libraries for antibacterial activity Discovery efforts will focus on World Health Organization's priority pathogens The Global Antibiotic Research and Development Partnership is partnering with Calibr, the Helmholtz Centre for Infection Research, in particular its location Helmholtz-Institute for Pharmaceutical Research Saarland, and the University of Queensland's Community for Open Antimicrobial Drug Discovery in its efforts to develop and ensure new antibiotics are globally available to all patients who need them.

11 Apr 2019