Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Donanemab: A trailblazer for Alzheimer's disease treatment?

A recent study evaluated the efficacy and side effects of donanemab, an antibody that could possibly clear brain amyloid plaque in early symptomatic Alzheimer disease (AD).

20 Jul 2023

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Researchers evaluated the impact of Lewy body (LB) positivity (+) on clinical outcomes such as cognition and smell among cognitively.

20 Jul 2023

Early treatment for multiple sclerosis linked to lower disability risk

People who start taking medication soon after the first signs of multiple sclerosis (MS) may have a lower risk of disability later, according to a study published in the July 19, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Jul 2023

Vitamin B-related amino acids may increase dementia risk from air pollution

Higher levels of vitamin B-related amino acids may be linked to the risk of dementia associated with a certain type of air pollutants called particulate matter, according to a study published in the July 19, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Jul 2023

New protein discovered in Alzheimer's brains could lead to better diagnosis and treatment

Alzheimer's is considered a disease of old age, with most people being diagnosed after 65. But the condition actually begins developing out of sight many years before any symptoms emerge.

19 Jul 2023

Finger prick blood sample can detect Alzheimer's biomarkers

Advancements in technology and practice reported for the first time at AAIC 2023 demonstrate the simplicity, transportability and diagnostic value of blood-based biomarkers for Alzheimer's, including the future potential for at-home testing by a patient or a family member.

19 Jul 2023

Espresso compounds inhibit tau protein aggregation in preliminary in vitro tests

Whether enjoyed on its own or mixed into a latte, Americano or even a martini, espresso provides an ultra-concentrated jolt of caffeine to coffee lovers.

19 Jul 2023

Older adults see the benefit in cognitive screening, but many have not been tested

Eighty percent of older adults see the benefit of tests that can give an early warning that a person's memory and thinking abilities have started to decline, a new poll of people age 65 to 80 finds.

19 Jul 2023

The brain structure of superagers: identifying demographic, lifestyle, and clinical factors associated with their phenotype

Researchers used machine learning models to assess the physical and primarily mental performance of superagers.

19 Jul 2023

A machine-learning approach for monitoring the progression of Alzheimer's disease

Researchers evaluate the predictive value of a multidimensional machine learning approach for monitoring the progression of Alzheimer’s disease.

19 Jul 2023

Hearing aids may offer protection against cognitive decline in older adults at high risk of dementia

While hearing aids and audiological support services did not have any impact on cognitive decline over 3 years in a general population of older adults, treating hearing loss protected against cognitive decline in older adults at greater risk of dementia.

18 Jul 2023

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Francesca Marassi, PhD, professor and chair of biophysics at the Medical College of Wisconsin (MCW), has been awarded a five-year, $13 million program project grant (PPG) by the National Institutes of Health (NIH) to study misplaced calcification in the eyes and brains of patients suffering from age-related macular degeneration (AMD) and Alzheimer's disease (AD).

18 Jul 2023

Spinal fluid test could be used for early detection of Lewy body disease

Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test.

18 Jul 2023

IU researchers present groundbreaking findings at Alzheimer's conference

Researchers from Indiana University School of Medicine had a large presence and leadership role at the 2023 Alzheimer's Association International Conference in Amsterdam, Netherlands, with involvement in more than 150 presentations at the four-day meeting.

18 Jul 2023

Donanemab may offer new hope for people with early Alzheimer's disease

The data reported today by Eli Lilly from the TRAILBLAZER-ALZ 2 clinical trial of donanemab in early symptomatic Alzheimer's disease demonstrate an important advancement in Alzheimer's research and treatment.

17 Jul 2023

COVID-19 vaccines saved lives of older adults with dementia in long-term care

Deaths among older adults with dementia fell starkly in nursing homes and long-term care centers after COVID-19 vaccinations became available, yet remained high for those living at home, according to a new study led by UC San Francisco.

17 Jul 2023

Donanemab shows promise in slowing Alzheimer's disease

With yet a third new Alzheimer's drug expected to be approved by the Food and Drug Administration (FDA), the field is beginning to show progress in the fight to slow the disease.

17 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

First-ever county-level estimates of Alzheimer's prevalence released at AAIC 2023

The first-ever county-level estimates of the prevalence of people with Alzheimer's dementia — in all 3,142 United States counties — were released today at the Alzheimer's Association International Conference 2023, in Amsterdam, Netherlands, and online.

17 Jul 2023

New proteomic insights: cerebrospinal fluid biomarkers show promise in detecting dementia with Lewy bodies

Researchers conducted cerebrospinal fluid (CSF) proteome profiling and identified CSF proteins.

17 Jul 2023

Alzheimer's Disease News and Research

Further Reading

Donanemab: A trailblazer for Alzheimer's disease treatment?

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Early treatment for multiple sclerosis linked to lower disability risk

Vitamin B-related amino acids may increase dementia risk from air pollution

New protein discovered in Alzheimer's brains could lead to better diagnosis and treatment

Finger prick blood sample can detect Alzheimer's biomarkers

Espresso compounds inhibit tau protein aggregation in preliminary in vitro tests

Older adults see the benefit in cognitive screening, but many have not been tested

The brain structure of superagers: identifying demographic, lifestyle, and clinical factors associated with their phenotype

A machine-learning approach for monitoring the progression of Alzheimer's disease

Hearing aids may offer protection against cognitive decline in older adults at high risk of dementia

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Spinal fluid test could be used for early detection of Lewy body disease

IU researchers present groundbreaking findings at Alzheimer's conference

Donanemab may offer new hope for people with early Alzheimer's disease

COVID-19 vaccines saved lives of older adults with dementia in long-term care

Donanemab shows promise in slowing Alzheimer's disease

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

First-ever county-level estimates of Alzheimer's prevalence released at AAIC 2023

New proteomic insights: cerebrospinal fluid biomarkers show promise in detecting dementia with Lewy bodies

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