Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

SOX9 broadly modifies the severity of Alagille syndrome liver disease in mice

Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues.

11 Oct 2019

Study investigates how aging influences fate of fibro-adipogenic progenitors in skeletal muscles

In adult skeletal muscle, loss of myofiber integrity caused by mechanical injuries or diseases are repaired by resident muscle stem cells, called satellite cells, which promptly exit from quiescence after disruption of muscle architecture to expand, differentiate and drive tissue regeneration.

11 Oct 2019

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

In adolescent and adult patients with cystic fibrosis taking lumacaftor-ivacaftor (ORKAMBI), the combination drug appears to improve lung function and body weight and reduce the need for intravenous antibiotic treatment, according to a French study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

11 Oct 2019

Vaccine against gastrin may slow spread of pancreatic cancer

New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.

10 Oct 2019

Researchers identify genetic mutation that causes idiopathic pulmonary fibrosis

Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis by killing the cells lining the lung's airways.

10 Oct 2019

UD engineering professor receives NIH grant to accelerate study of lung fibrosis

University of Delaware Professor April Kloxin has been awarded a National Institutes of Health Director's New Innovator Award from the NIH Common Fund's High-Risk, High-Reward Research program, which supports highly innovative research proposals.

9 Oct 2019

Peripherally inserted central catheters associated with serious allergic reactions in patients

Peripherally inserted central catheters (PICCs) that use a magnetized tip to guide insertion were associated with serious allergic reactions in patients, according to a study published today in Infection Control & Hospital Epidemiology, the journal for the Society for Healthcare Epidemiology of America. Severe adverse reactions occurred in patients within minutes of PICC insertion.

8 Oct 2019

Study identifies a common denominator that triggers asthma in favorable environments

In recent decades, asthma has become a major public health problem. The exponential increase in asthma cases in industrialized countries over the past 50 years is due to major changes in our environment.

7 Oct 2019

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

Cincinnati Children's Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic gastrointestinal disorders.

7 Oct 2019

Researchers identify new targets to treat fibrotic diseases

When it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. Fibroblasts give rise to healing cells called myofibroblasts, which generally is good in the short term - but bad when myofibroblast activation gets out of hand.

4 Oct 2019

$28 million grant supports Cincinnati Children's role as coordinating center for Rare Diseases Clinical Research Network

The federal agency that oversees a large network of research centers seeking cures for hundreds of rare, disabling and often fatal diseases has named Cincinnati Children's as its new data management and coordinating center.

4 Oct 2019

Fewer than half of U.S. adults get annual flu shot, shows study

So far this calendar year, 1,243 people scattered around 31 states had confirmed measles, the highest number of measles cases reported in the U.S.

3 Oct 2019

Nanoparticles moving through airway mucus may predict severity of COPD

In a proof-of-concept experiment, researchers from Johns Hopkins Medicine say they have successfully used microscopic man-made particles to predict the severity of patients' chronic obstructive pulmonary disease by measuring how quickly the particles move through mucus samples.

30 Sep 2019

New imaging systems can help diagnose heart disease

Researcher and professor Lasse Løvstakken starts a video on his computer screen. We're in the eye of a storm. It looks almost like a hurricane approaching a coastline.

30 Sep 2019

Nintedanib drug can benefit patients with broad range of scarring lung diseases

Nintedanib, a medication approved for the treatment of idiopathic pulmonary fibrosis, slows the decline in lung function among patients with a broad range of scarring lung diseases.

30 Sep 2019

Smart shirt technology is a promising tool for monitoring lung disease

A smart shirt that measures lung function by sensing movements in the chest and abdomen has proved to be accurate when compared to traditional testing equipment, according to research presented at the European Respiratory Society International Congress.

30 Sep 2019

Fibrosis News and Research

Further Reading

SOX9 broadly modifies the severity of Alagille syndrome liver disease in mice

Study investigates how aging influences fate of fibro-adipogenic progenitors in skeletal muscles

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

Vaccine against gastrin may slow spread of pancreatic cancer

Researchers identify genetic mutation that causes idiopathic pulmonary fibrosis

UD engineering professor receives NIH grant to accelerate study of lung fibrosis

Peripherally inserted central catheters associated with serious allergic reactions in patients

Study identifies a common denominator that triggers asthma in favorable environments

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

Researchers identify new targets to treat fibrotic diseases

$28 million grant supports Cincinnati Children's role as coordinating center for Rare Diseases Clinical Research Network

Fewer than half of U.S. adults get annual flu shot, shows study

Nanoparticles moving through airway mucus may predict severity of COPD

New imaging systems can help diagnose heart disease

Nintedanib drug can benefit patients with broad range of scarring lung diseases

Smart shirt technology is a promising tool for monitoring lung disease

Vapors from tank-style e-cigarettes have higher concentrations of harmful metals

Better methods needed to identify people at risk for liver disease

Study may lead to earlier detection of heart failure and new targeted treatments

New protein could offer a fresh target for cancer treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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