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Ginseng genome unlocks secrets of medicinal benefits

A landmark study has successfully decoded the complete ginseng genome, unveiling the genetic mechanisms that govern saponin biosynthesis. This detailed genetic map illuminates the evolutionary and metabolic pathways of Panax ginseng, a staple in traditional medicine. This pivotal discovery promises to drive forward breeding initiatives and augment the plant's medicinal qualities, unlocking new possibilities for therapeutic applications.

19 Jul 2024

Museum flies and wild specimens help fill gaps in fruit fly evolution

A multitude of new genomic sequence data fills major gaps in the fruit fly tree of life, Bernard Kim from Stanford University, US, and colleagues report in the open-access journal PLOS Biology, publishing July 18th.

19 Jul 2024

New study links cellular health to well-being of dementia caregivers

It's no secret that the caregivers of spouses with memory impairment face enormous amounts of stress.

18 Jul 2024

Type 1 diabetes in children linked to increased risk of mental health problems

Children diagnosed with type 1 diabetes are at significantly higher risk of a number of mental health issues, including mood and anxiety disorders, a study from a team in the UK and the Czech Republic has found.

18 Jul 2024

CU Boulder research uncovers role of endogenous retroviruses in cancer

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago.

18 Jul 2024

Novel method enables RNA detection with Cas12 nucleases

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

17 Jul 2024

E. coli genomic analysis uncovers antibiotic resistance mechanisms in dogs

Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.

16 Jul 2024

Researchers reveal unique characteristics of previously unexplored protein FAM110A

An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies and Institute of Clinical and Experimental Pharmacology and Toxicology, University of Freiburg), Dr. Libor Macurek (Institute of Molecular Genetics, Czech Academy of Sciences, Prague) and Dr. Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague) has uncovered a new mechanism of the crosstalk between microtubules and actin cytoskeleton during cell division and revealed unique characteristics of the previously unexplored protein FAM110A.

16 Jul 2024

UChicago expands microbiome research capabilities with new manufacturing facility

The Duchossois Family Institute (DFI) at the University of Chicago can manufacture clinical-grade encapsulated bacteria – catalyzing opportunities to better understand the microbiome and its myriad of roles in human health.

16 Jul 2024

Genetic marker predicts gabapentin response in chronic pelvic pain

Women who carry a particular form of a pain gene are more likely to respond well to a common medication used to treat long-term discomfort, research shows.

15 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

Study finds dried fruit consumption lowers type 2 diabetes risk

Recent research shows that higher dried fruit intake is linked to a reduced risk of type 2 diabetes, highlighting potential health benefits despite its sugar content.

14 Jul 2024

Lifestyle changes can greatly reduce heart disease risk in people with high genetic risk

Study highlights the significant impact of genetic risk and lifestyle on early- and late-onset cardiovascular diseases, showing that lifestyle improvements can notably reduce CVD risk, especially in high genetic risk individuals.

14 Jul 2024

Gene editing silences mutant microRNA, restores hearing in adult mice

Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss. They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled the animals to regain hearing. The approach by a research team supported by the National Institutes of Health (NIH), reported in Science Translational Medicine, may eventually lead to potential treatments for inherited hearing loss in people.

13 Jul 2024

Groundbreaking mRNA vaccine administered to captive elephant to fight EEHV

Colossal, the de-extinction company, announces that the mRNA vaccine it helped to provide research support and acceleration funding for has been administered to the first elephant in captivity.

13 Jul 2024

Novel DNA aptamers of melanopsin developed to regulate circadian rhythm

DNA aptamers of melanopsin that regulate the clock hands of biological rhythms were developed by the Toyohashi University of Technology and the National Institute of Advanced Industrial Science and Technology (AIST) group.

12 Jul 2024

ARPP21 gene mutation could be the cause of ALS

Researchers from the Neuromuscular Diseases Group and the Dementia Neurobiology Group of the Sant Pau Research Institute (IR Sant Pau) and the Memory Unit of the Sant Pau Hospital, led by neurologist Dr. Ricard Rojas-García, have identified a new mutation in the ARPP21 gene that could be the cause of Amyotrophic Lateral Sclerosis (ALS), a devastating neurodegenerative disease.

11 Jul 2024

New study reveals the genetic cause of Parkinson's disease

According to Science Alert, neuroscientists from Johns Hopkins University have recently discovered a new treatment for Parkinson's disease using an FDA-approved cancer drug.

11 Jul 2024

Study reveals how DDM1 protein suppresses 'jumping genes' in plants

International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of "jumping genes."

11 Jul 2024

Prime editing offers promising path to permanent treatment for cystic fibrosis

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection.

11 Jul 2024