Immune System News and Research

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Salt can induce and worsen pathogenic immune system responses in mice

For the past few decades, health officials have been reporting increases in the incidence of autoimmune diseases such as multiple sclerosis (MS). Now researchers at Yale School of Medicine, Harvard Medical School and the Broad Institute have identified a prime suspect in the mystery - dietary salt.

7 Mar 2013

Study combines induced pluripotent stem cell technology and genetic correction to treat DMD

Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in a mouse model for Duchenne Muscular Dystrophy (DMD).

7 Mar 2013

Study shows how fish oils help lower blood pressure via vasodilation at ion channels

Omega-3 fatty acids found in oily fish may have diverse health-promoting effects, potentially protecting the immune, nervous, and cardiovascular systems.

6 Mar 2013

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Two brothers have been cured of their sickle cell disease at the University of Illinois Hospital & Health Sciences System using a relatively uncommon type of stem cell transplant that is performed without chemotherapy.

6 Mar 2013

Aerobic walking program alleviates lower back pain, says Tel Aviv University researcher

Lower back pain is a common complaint, and treatment often requires many hours of physical therapy over multiple weekly clinic visits - a costly commitment.

6 Mar 2013

New research findings could lead to development of effective therapies for anxiety disorders

Researchers at Boston University School of Medicine have, for the first time, identified a specific group of cells in the brainstem whose activation during rapid eye movement sleep is critical for the regulation of emotional memory processing.

6 Mar 2013

SIRT1 gene may be involved in development of type 1 diabetes

A JDRF-funded study out of Switzerland has shown that a single gene called SIRT1 may be involved in the development of type 1 diabetes (T1D) and other autoimmune diseases. The study, "Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes," was published today in Cell Metabolism and represents the first demonstration of a monogenetic defect leading to the onset of T1D.

6 Mar 2013

Scientists decode the antihypertensive impact of omega-3 fatty acids

Scientists of Friedrich Schiller University Jena and Jena University Hospital decode the antihypertensive impact of omega-3 fatty acids. In two newly published articles for the well-known science magazine 'Proceedings of the National Academy of Sciences, USA' they describe how they analyzed the impact of omega-3 fatty acids on a systemic level and they also described the underlying molecular mechanisms for the first time.

6 Mar 2013

National Jewish Health receives U.S. patent for POPG and related compounds

Dennis Voelker, PhD, professor of medicine at National Jewish Health, has been awarded a U.S. patent (#8,367,643) for various lipids and related compounds that can inhibit inflammation and infection in the lungs, especially those caused by influenza and respiratory syncytial virus (RSV).

5 Mar 2013

Viewpoints: Disappointing 'surprises' in health law; Cuts in graduate medical training threatens physician supply; Va. can afford Medicaid expansion

The proposed 2.3 percent reduction in (Medicare Advantage plan) payments, which comes on top of cuts already scheduled under the Affordable Care Act, pays no mind to the potential impact on quality of care throughout the program. These cuts will apply to all plans no matter the value they bring in providing quality care to beneficiaries or offering innovative solutions that could ultimately be scaled and applied to the broader program.

5 Mar 2013

Left-sided brain injury increases infection risk

Patients with a left-sided brain injury are more likely to develop hospital-acquired infections than those with right-sided injury, show study findings.

5 Mar 2013

Forceps delivery ‘does not increase atopy risk’

Results from a population-based cohort study suggest that forceps-assisted birth is associated with an increased risk for asthma, but not allergic sensitization, in later childhood.

5 Mar 2013

HIV might promote aging and disease progression in people with HCV, study results suggest

Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus, co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.

5 Mar 2013

Results of two important studies published in March issue of AIDS

The results of two important studies have been published in the March issue of AIDS, the official journal of the International AIDS Society. One study notes that screening for HIV should be performed more frequently—up to every three months for the highest-risk patients, while low-risk groups to be tested every three years. A second study demonstrates a link between heavy drinking and risky behaviors for men who have sex with men (MSM).

5 Mar 2013

Study highlights long-term benefits of early antiretroviral therapy initiated in infants

A study led by University of Massachusetts Medical School professor and immunologist Katherine Luzuriaga, MD, and Johns Hopkins Children's Center virologist Deborah Persaud, MD, highlights the long-term benefits of early antiretroviral therapy (ART) initiated in infants.

5 Mar 2013

Eating your greens may be even more important than previously thought

Eating your greens may be even more important than previously thought, with the discovery that an immune cell population essential for intestinal health could be controlled by leafy greens in your diet.

5 Mar 2013

Overall risk of infection associated with most neuroangiographic procedures is very low

Patients undergoing cerebral angiography and neurointerventional procedures on the brain are at very low risk of infection-even without preventive antibiotics, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

5 Mar 2013

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Pfizer Inc. presented today the results from a Phase 3 study demonstrating the immunogenicity, tolerability and safety of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine Diphtheria CRM197 Protein)in adults infected with human immunodeficiency virus (HIV).

5 Mar 2013

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex to target with a drug since it is also crucial to the healthy functioning of many immune cells in the body, not just B cells gone bad.

4 Mar 2013

Prompt antiretroviral therapy may help infants clear the HIV and achieve long-term remission

A team of researchers from Johns Hopkins Children's Center, the University of Mississippi Medical Center and the University of Massachusetts Medical School describe the first case of a so-called "functional cure" in an HIV-infected infant. The finding, the investigators say, may help pave the way to eliminating HIV infection in children.

4 Mar 2013

Immune System News and Research

Salt can induce and worsen pathogenic immune system responses in mice

Study combines induced pluripotent stem cell technology and genetic correction to treat DMD

Study shows how fish oils help lower blood pressure via vasodilation at ion channels

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Aerobic walking program alleviates lower back pain, says Tel Aviv University researcher

New research findings could lead to development of effective therapies for anxiety disorders

SIRT1 gene may be involved in development of type 1 diabetes

Scientists decode the antihypertensive impact of omega-3 fatty acids

National Jewish Health receives U.S. patent for POPG and related compounds

Viewpoints: Disappointing 'surprises' in health law; Cuts in graduate medical training threatens physician supply; Va. can afford Medicaid expansion

Left-sided brain injury increases infection risk

Forceps delivery ‘does not increase atopy risk’

HIV might promote aging and disease progression in people with HCV, study results suggest

Results of two important studies published in March issue of AIDS

Study highlights long-term benefits of early antiretroviral therapy initiated in infants

Eating your greens may be even more important than previously thought

Overall risk of infection associated with most neuroangiographic procedures is very low

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

Prompt antiretroviral therapy may help infants clear the HIV and achieve long-term remission

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