Immune System News and Research

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Study instructs how to design new, more powerful vaccine formulas for cancer

Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

4 Mar 2013

Investigators identify seven new genetic regions associated with AMD

An international group of investigators has identified seven new genetic regions associated with age-related macular degeneration (AMD), a common cause of blindness in older individuals. The findings, reported online March 3 in Nature Genetics, could point to new biological pathways and therapeutic targets for AMD.

4 Mar 2013

Workshop to help physicians and clinicians increase job satisfaction and prevent burnout

On Saturday, May 11, the Center for Mindfulness at University of California, San Diego School of Medicine is hosting a workshop to help physicians and clinicians increase job satisfaction and prevent burnout. The program will show participants how to incorporate the concept of mindfulness into their daily clinical practice with the long-term goal of enhancing patient-centered care and physician well-being through compassionate communication.

4 Mar 2013

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell.

3 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

NPR blog examines debate over option B+ HIV prevention strategy

NPR's "Shots" blog examines the debate over Option B+, a strategy to prevent mother-to-child HIV transmission that "aims to put every pregnant woman with HIV on triple-drug treatment and keep her on it for the rest of her life -- even if the virus has not yet damaged her immune system to the point where she needs medications to preserve her own health."

2 Mar 2013

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune response unable to kill off the tumour's cancerous cells.

2 Mar 2013

Combination of two environmental factors contributes to schizophrenia

The interplay between an infection during pregnancy and stress in puberty plays a key role in the development of schizophrenia, as behaviourists from ETH Zurich demonstrate in a mouse model. However, there is no need to panic.

2 Mar 2013

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, but these therapies can leave patients vulnerable to infection.

2 Mar 2013

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus.

2 Mar 2013

Influenza vaccine linked to narcolepsy in children in England

Researchers have found an increased risk for narcolepsy in children who received the swine flu vaccination in England.

1 Mar 2013

Macrophages allow entry of HIV in the urethra

Having suggested in 2011 that the urethra is a novel entry site for HIV, a team from the Institut Cochin, has now confirmed this hypothesis and identified the cells and mechanisms brought into play: the immune system cells macrophages, present in the epithelium of the urethra, allow the entry of HIV. This work, published online on the website of the journal Mucosal Immunology, could make it possible to test novel HIV/AIDS prevention strategies.

1 Mar 2013

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for under-served medical needs in neurology and cardiology, announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).

1 Mar 2013

Not all acne bacteria trigger pimples: Study

The bacteria that cause acne live on everyone's skin, yet one in five people is lucky enough to develop only an occasional pimple over a lifetime.

1 Mar 2013

Exposure to BPA may increase risk of asthma in young children

Researchers at the Columbia Center for Children's Environmental Health at the Mailman School of Public Health are the first to report an association between early childhood exposure to the chemical bisphenol A (BPA) and an elevated risk for asthma in young children. BPA is a component of some plastics and is found in food can liners and store receipts.

1 Mar 2013

Griffith University's Institute for Glycomics launches human trials for Streptococcus A vaccine

Griffith University's Institute for Glycomics has launched human trials for a vaccine against Streptococcus A, the germ that causes rheumatic fever.

1 Mar 2013

Anti-LG3 associated with high rate of organ rejection during transplantation

A team led by Dr. Marie-Jos-e H-bert from the University of Montreal Hospital* Research Centre (CRCHUM) has discovered a new cause of organ rejection in some kidney transplant patients. Her team has identified a new class of antibodies - anti-LG3 - which when activated lead to severe rejection episodes associated with a high rate of organ loss.

28 Feb 2013

Mutant HSP70i protein may offer potent treatment opportunities for vitiligo

Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune responses in human skin tissue samples.

28 Feb 2013

EpiCept fourth quarter revenue decreases to $0.1 million

EpiCept Corporation today announced operating and financial results for the fourth quarter and full year ended December 31, 2012, and provided an update on the Company's merger with Immune Pharmaceuticals, Ltd. (Immune).

28 Feb 2013

Researchers identify 25 human proteins that may be crucial for HIV-1 infection and survival

Studying HIV-1, the most common and infectious HIV subtype, Johns Hopkins scientists have identified 25 human proteins "stolen" by the virus that may be critical to its ability to infect new cells. HIV-1 viruses capture many human proteins from the cells they infect but the researchers believe these 25 proteins may be particularly important because they are found in HIV-1 viruses coming from two very different types of infected cells.

28 Feb 2013

Immune System News and Research

Study instructs how to design new, more powerful vaccine formulas for cancer

Investigators identify seven new genetic regions associated with AMD

Workshop to help physicians and clinicians increase job satisfaction and prevent burnout

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

NPR blog examines debate over option B+ HIV prevention strategy

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

Combination of two environmental factors contributes to schizophrenia

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Influenza vaccine linked to narcolepsy in children in England

Macrophages allow entry of HIV in the urethra

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Not all acne bacteria trigger pimples: Study

Exposure to BPA may increase risk of asthma in young children

Griffith University's Institute for Glycomics launches human trials for Streptococcus A vaccine

Anti-LG3 associated with high rate of organ rejection during transplantation

Mutant HSP70i protein may offer potent treatment opportunities for vitiligo

EpiCept fourth quarter revenue decreases to $0.1 million

Researchers identify 25 human proteins that may be crucial for HIV-1 infection and survival

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