Tumor News and Research

RSS

Interim results from CEL-SCI's Multikine Phase III study on head and neck cancer

CEL-SCI Corporation announced today that an interim review of the safety data from its open label, randomized, controlled, pivotal Phase III study of Multikine (Leukocyte Interleukin, Injection) investigational immunotherapy by an Independent Data Monitoring Committee (IDMC) raised no safety concerns.

23 Oct 2012

Glioblastoma multiforme can originate from cortical neurons

Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science Express, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

23 Oct 2012

$Ustekinumab success in refractory Crohn’s disease$

Ustekinumab success in refractory Crohn’s disease

Patients with Crohn’s disease who have failed to respond adequately to anti–tumor necrosis factor treatment may benefit from the monoclonal antibody ustekinumab, results of a double-blind, placebo-controlled trial suggest.

22 Oct 2012

Study describes design and effectiveness of NIR responsive gold nanorods for chemotherapy

Excitement around the potential for targeted nanoparticles (NPs) that can be controlled by stimulus outside of the body for cancer therapy has been growing over the past few years. More specifically, there has been considerable attention around near-infrared (NIR) light as an ideal method to stimulate nanoparticles from outside the body.

19 Oct 2012

ACT TIL therapy effective in treating metastatic melanoma

Researchers at Moffitt Cancer Center have carried out a clinical trial in which patients with metastatic melanoma were given chemotherapy and an immunotherapy of adoptive cell transfer (ACT) with tumor infiltrating lymphocytes (TIL).

19 Oct 2012

Breast-feeding associated with reduced risk of ER/PR-negative breast cancer

Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health.

19 Oct 2012

Minnelide gives new hope for patients with pancreatic cancer

A new drug created at the University of Minnesota may hold the answer to defeating pancreatic cancer, according to results published today in the prestigious journal Science Translational Medicine.

19 Oct 2012

Ustekinumab shows positive results in decreasing debilitating effects of Crohn's Disease

Ustekinumab, an antibody proven to treat the skin condition psoriasis, has now shown positive results in decreasing the debilitating effects of Crohn's Disease, according to researchers at the University of California San Diego, School of Medicine.

18 Oct 2012

Research may lead to new ways to identify women with breast cancer risks from low-dose radiation

Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory have identified tissue mechanisms that may influence a woman's susceptibility or resistance to breast cancer after exposure to low-dose ionizing radiation, such as the levels used in full-body CT scans and radiotherapy.

18 Oct 2012

Cytokine levels altered in FEP, schizophrenia patients

Levels of certain cytokines are altered in patients with first-episode psychosis and patients with schizophrenia, research shows.

17 Oct 2012

DNA damage response contains previously unknown components: Study

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida; Duke University; Johns Hopkins University; the Brazilian National Cancer Institute; and the Rio de Janeiro Federal Institute of Education, Science and Technology have discovered that an intricate system to repair DNA damage called the "DNA damage response" (DDR) contains previously unknown components, including proteins that could be targeted as sensitizers for chemotherapy.

17 Oct 2012

UMB, UMCP to develop small robot that could help neurosurgeons in removing brain tumors

A research team from the University of Maryland, College Park (UMCP) and the University of Maryland, Baltimore (UMB) have been awarded a new $2 million grant from the National Institutes of Health (NIH) to continue developing a small robot that could one day be a huge aid to neurosurgeons in removing difficult-to-reach brain tumors.

17 Oct 2012

Universal tumor testing superior to selective strategy in identifying Lynch syndrome among CRC patients

In a comparison of strategies to identify individuals with Lynch syndrome, the most common form of hereditary colorectal cancer (CRC), caused by mutations in certain genes (DNA mismatch repair [MMR] genes), universal tumor MMR testing among certain CRC patients had a greater sensitivity for the identification of Lynch syndrome compared with multiple alternative strategies, although the diagnostic improvement was modest, according to a study in the October 17 issue of JAMA.

17 Oct 2012

Stat5 protein could serve as biomarker to help guide prostate cancer treatment

Men who had high levels of the activated Stat5 protein in their prostate cancer after a radical prostatectomy were more likely to have a recurrence or die from the disease compared to men who had little to no presence of the growth protein, according to a recent study published in Human Pathology by Jefferson's Kimmel Cancer Center researchers.

17 Oct 2012

Study determines how Trop2 protein drives growth of tumor cells in prostate and other epithelial cancers

Researchers led by Tanya Stoyanova and Dr. Owen Witte of UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have determined how a protein known as Trop2 drives the growth of tumor cells in prostate and other epithelial cancers.

17 Oct 2012

Salk findings on cold virus proteins may spur new cancer treatments

Cold viruses generally get a bad rap----which they've certainly earned----but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ally in the fight against cancer.

17 Oct 2012

Recurrent patterns of genomic imbalances determine evolution of invasive breast cancer

Ductal carcinoma in situ (DCIS) is considered a precursor lesion for invasive breast cancer if untreated, and is found in approximately 45% of patients with invasive ductal carcinoma (IDC). Patients with DCIS only (not accompanied by invasive disease) have a 5-year-survival of nearly 100%, compared to 89% for all stages of invasive breast cancer (24% for patients with distant metastasis).

17 Oct 2012

Tumor News and Research

Interim results from CEL-SCI's Multikine Phase III study on head and neck cancer

Glioblastoma multiforme can originate from cortical neurons

Ustekinumab success in refractory Crohn’s disease

Study describes design and effectiveness of NIR responsive gold nanorods for chemotherapy

ACT TIL therapy effective in treating metastatic melanoma

Breast-feeding associated with reduced risk of ER/PR-negative breast cancer

Minnelide gives new hope for patients with pancreatic cancer

Ustekinumab shows positive results in decreasing debilitating effects of Crohn's Disease

Research may lead to new ways to identify women with breast cancer risks from low-dose radiation

Cytokine levels altered in FEP, schizophrenia patients

DNA damage response contains previously unknown components: Study

UMB, UMCP to develop small robot that could help neurosurgeons in removing brain tumors

Universal tumor testing superior to selective strategy in identifying Lynch syndrome among CRC patients

Stat5 protein could serve as biomarker to help guide prostate cancer treatment

Study determines how Trop2 protein drives growth of tumor cells in prostate and other epithelial cancers

Salk findings on cold virus proteins may spur new cancer treatments

Recurrent patterns of genomic imbalances determine evolution of invasive breast cancer

Experts blaze TRAIL for pulmonary arterial hypertension therapy

First analysis of IASLC malignant pleural mesothelioma database

Thymic stromal lymphopoietin molecule makes mice resistant to skin cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News