Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has honored Philipp E. Scherer, PhD, with the 15th Naomi Berrie Award for Outstanding Research in Diabetes, for his work that helped usher in a new understanding of fat and its role in diabetes and other metabolic diseases. His discovery of adiponectin, a hormone produced by fat, helped transform the scientific concept of fat as an inert storage depot to one of it as an endocrine "organ" that exerts control over the brain, muscles, and other organs. The award, given annually by CUMC's Naomi Berrie Diabetes Center, is Columbia's top honor for excellence in diabetes research.

19 Nov 2013

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

Despite high expectations for the commonly used diabetes drug metformin to improve risk factors for heart disease in people without diabetes, few beneficial effects have been found in a randomised trial of patients with established cardiovascular disease, published in The Lancet Diabetes & Endocrinology.

7 Nov 2013

Simple urine test can help identify disease risks in young type 1 diabetes patients

Using a simple urine test, researchers can now identify young people with type 1 diabetes at risk of heart and kidney disease. The new research, funded by JDRF, Diabetes UK, and the British Heart Foundation, was published today, 06 November, in the journal Diabetes Care.

7 Nov 2013

Wild blueberries: 2 cups a day may keep the doctor away

Wild blueberries are a rich source of phytochemicals called polyphenols, which have been reported by a growing number of studies to exert a wide array of protective health benefits. A new study by researchers at the University of Maine adds to this growing body of evidence.

6 Nov 2013

Use of testosterone therapy after angiography associated with increased risk of death

Among a group of men who underwent coronary angiography and had a low serum testosterone level, the use of testosterone therapy was associated with increased risk of death, heart attack, or ischemic stroke, according to a study in the November 6 issue of JAMA.

6 Nov 2013

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Making fat cells immortal might seem like a bad idea to most people, but for a team of University of Iowa scientists it was the ideal way to study how the interaction between bacteria and fat cells might contribute to diabetes.

31 Oct 2013

Protective effect of estrogen in women with NASH against development of severe fibrosis

New research suggests that estrogen protects women with nonalcoholic steatohepatitis (NASH) from severe liver fibrosis. According to the study published online in Hepatology, a journal of the American Association for the Study of Liver Diseases, men are at higher risk of more severe fibrosis compared to women prior to menopause, but liver fibrosis severity is similar in men and post-menopausal women.

30 Oct 2013

Researchers discover novel genetic cause of severe obesity

Researchers from the University of Cambridge have discovered a novel genetic cause of severe obesity which, although relatively rare, demonstrates for the first time that genes can reduce basal metabolic rate - how the body burns calories.

25 Oct 2013

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

Research from Boston University School of Medicine suggests that testosterone treatment in hypogonadal (testosterone deficient) men restores normal lipid profiles and may reduce the risk of cardiovascular disease. These finding currently appear online in the International Journal of Clinical Practice.

24 Oct 2013

Inflammation causally linked to functional decline in aging

Inflammation is the common denominator of many chronic age-related diseases such as arthritis, gout, Alzheimer's, and diabetes. But according to a Yale School of Medicine study, even in the absence of a disease, inflammation can lead to serious loss of function throughout the body, reducing healthspan - that portion of our lives spent relatively free of serious illness and disability.

23 Oct 2013

High-intensity interval training with Mediterranean diet counselling 'supersizes' heart health

Lifestyle programs focused on high-intensity interval training combined with nutritional counselling on the Mediterranean diet have shown dramatic results for improving the heart health of people with abdominal obesity, finds a study released at the Canadian Cardiovascular Congress.

18 Oct 2013

New less invasive surgical method paves way for development of efficient anti-obesity therapies

Bariatric surgeries, such as a gastric bypass, are currently the most effective anti-obesity therapies. They also lead to a reduced insulin resistance. However, the pitfall of these surgical interventions is that they are highly invasive and often permanent procedures.

11 Oct 2013

NUS, A*STAR establish joint center to study role of nutrition and development in health, disease in Asia

The National University of Singapore (NUS) and A*STAR will be jointly establishing the S$148 million Singapore Centre for Nutritional Sciences, Metabolic Diseases, and Human Development (SiNMeD).

11 Oct 2013

Hyperglycemia heightens pneumonia risk in pediatric burns patients

Research indicates that hyperglycemia puts pediatric burns patients at increased risk for pneumonia.

8 Oct 2013

Study shows PTSD increases individual's risk of metabolic syndrome

People suffering from post-traumatic stress disorder (PTSD) face a greater risk of cardiovascular disease and death. A new study involving a comprehensive review of the medical literature shows that PTSD also increases an individual's risk of metabolic syndrome.

3 Oct 2013

New insights into how obesity, type 2 diabetes can create stress response in the brain

Joslin researchers have gained new insights into how obesity and type 2 diabetes can create a stress response in the brain, especially in the hypothalamus (the brain region that regulates appetite and energy production), that may contribute to altering metabolism throughout the body. The findings are reported in the October issue of the Journal of Clinical Investigation.

2 Oct 2013

Addition of walnuts to diet can protect against diabetes and heart disease in at-risk individuals

Medical researchers from the Yale-Griffin Prevention Research Center in Connecticut have found evidence suggestive that adding walnuts to one's diet can protect against diabetes and heart disease in at-risk individuals.

24 Sep 2013

Causes of obesity, insulin resistance tied to fructose generated by the body

Researchers at the University of Colorado School of Medicine reported today that the cause of obesity and insulin resistance may be tied to the fructose your body makes in addition to the fructose you eat.

11 Sep 2013

NIH awards nearly $14M grants to research on how genetic factors influence susceptibility to disease

Five research teams have received new four-year awards to study the genomics of disease susceptibility in ethnically diverse populations. The projects aim to unravel the subtle variations in genetic makeup among groups - including African-Americans, Asian-Americans, Hispanics and more - that may account for differences in risks for conditions such as high blood pressure and high blood lipids, in addition to common diseases such as cancer and heart disease.

7 Sep 2013

NIH Funds Minority Disease Susceptibility Studies

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6 Sep 2013