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Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Boston College Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to study viral insulins and mechanisms related to IGF-1 receptor protein inhibition and its potential applications in cancer treatment.

26 Feb 2024

Globe artichokes: A rich source of dietary fiber and phenolic antioxidants

The clinical and nutraceutical health benefits of Cynarra scolymus, the globe artichoke.

26 Feb 2024

Understanding the role played by HIV in pulmonary hypertension

Across the globe, more than 39 million people are living with the Human Immunodeficiency Virus (HIV), the virus that causes AIDS, including more than 1.3 million new HIV diagnoses last year.

23 Feb 2024

Genetic variants influence blood pressure from early in life

Certain genes associated with hypertension affect blood pressure from early in life, and they increase the risk of cardiovascular disease as you get older. But you can do something about it.

23 Feb 2024

Study reveals over 134,000 missed cancer diagnoses in the U.S. during COVID-19 pandemic

Over 134,000 cancer cases went undiagnosed in the U.S. during the first 10 months of the COVID-19 pandemic, according to a new University of Kentucky Markey Cancer Center study.

23 Feb 2024

Cedars-Sinai researchers discover why some injured kidneys heal while others develop scarring

Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure.

22 Feb 2024

Machine learning model to determine associations between metabolic syndrome and lactation

Machine learning models to investigate the relationship of lactation with metabolic syndrome risk.

22 Feb 2024

Underutilized obesity treatments could transform patient health

When someone has obesity, losing even 5% of their body weight can make a major difference in their health -- especially if they can keep from regaining it.

21 Feb 2024

Targeting the Hippo signaling pathway to treat systemic sclerosis

Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease.

21 Feb 2024

Pioneering cell-based treatment for melanoma offered at Siteman Cancer Center

Siteman Cancer Center, based at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, is one of the first centers nationwide to offer a newly approved cell-based immunotherapy that targets melanoma.

20 Feb 2024

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine's mechanism of action has been unclear.

20 Feb 2024

NIH-funded research enhances genetic testing for health equity

To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.

20 Feb 2024

New RNA therapy zilebesiran shows promise in lowering blood pressure

Zilebesiran, an RNA interference therapeutic, significantly reduces blood pressure in hypertension patients with a favorable safety profile, offering a potential biannual treatment option.

19 Feb 2024

Selection, optimization, and validation of genetic tests for 10 common diseases

By analyzing millions of small genetic differences across a person's genome, researchers can calculate a polygenic risk score to estimate someone's lifetime odds of developing a certain disease.

19 Feb 2024

Evaluating a machine learning tool for predicting hospital-acquired acute kidney injury

Hospital-acquired acute kidney injury (HA-AKI) is a common complication in hospitalized patients that can lead to chronic kidney disease and is associated with longer hospital stays, higher health care costs and increased mortality.

16 Feb 2024

Heart attack survivors face higher risk of long-term health conditions

Having a heart attack significantly increases the risk of developing other serious long-term health conditions, a major new study shows.

16 Feb 2024

6th CKD Drug Development Summit: Countdown Begins

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From 6th CKD Drug Development Summit 16 Feb 2024

Ketogenic diet boosts brain's natural calm to combat epilepsy

A study in Cell Discovery shows the ketogenic diet increases brain GABA levels and the GABA/glutamate ratio through β-hydroxybutyric acid, offering a potential mechanism for its effectiveness in reducing epilepsy seizures.

15 Feb 2024

Good news for Valentine’s Day: Dark chocolate and champagne may improve heart health

It’s news you’ll love for Valentine’s Day: a leading health expert says the dark chocolates and bubbly you bought your sweetheart may also improve their heart health.

13 Feb 2024

Therapist-guided digital therapy reduces distress in people with long-term physical health conditions

A therapist-guided digital cognitive behavioural therapy reduced distress in 89 per cent of participants living with long-term physical health conditions, a new King's College London study finds.

13 Feb 2024