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Study shows potential of uric acid as add-on therapy for stroke

In a preclinical study, rodents treated with uric acid showed improved long-term outcomes after acute ischemic stroke. The findings suggest that the treatment may work as an add-on therapy to standard stroke treatments in humans.

17 Mar 2025

Neuropeptide Y identified as key driver of pancreatic cancer spread

Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolism 'switch' to help it spread, revealing a potential new treatment strategy for this highly aggressive disease.

17 Mar 2025

Yale research supports MRD detection for post-treatment lung cancer care

In the continuing evolution of personalized medicine, a new Yale study has found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer years after their treatment.

17 Mar 2025

Adding chemotherapy to radiotherapy does not improve outcomes for cervical cancer patients

Results from the NRG Oncology GOG-0263 phase III clinical trial testing the addition of cisplatin-based chemotherapy to adjuvant radiotherapy following radical hysterectomy and lymphadenectomy for patients with early-stage, intermediate-risk cervical carcinoma indicated that the addition of chemotherapy did not improve outcomes for patients and led to increased toxicity for patients.

14 Mar 2025

Fighting cancer, inflammation and unlocking dementia diagnostics

In recognition of their discovery of one of our immune system’s foundations, physician Andrea Ablasser, virologist Glen Barber and biochemist Zhijian J. Chen will be awarded the Paul Ehrlich and Ludwig Darmstaedter Prize 2025, endowed with €120,000, in Frankfurt’s Paulskirche today.

14 Mar 2025

Long-term study shows knee replacements last lifetime for active young adults

A 40-year study by Hospital for Special Surgery (HSS) researchers has found that active young adults who underwent total knee replacement were unlikely to require knee replacement revision in their lifetime, according to a new study shared today in a podium presentation at the American Academy of Orthopaedic Surgeons 2025 Annual Meeting.

14 Mar 2025

New method enhances precision in monitoring brain activity during deep brain stimulation

Mayo Clinic researchers have found a new way to more precisely detect and monitor brain cell activity during deep brain stimulation, a common treatment for movement disorders such as Parkinson's disease and tremor.

14 Mar 2025

Current state and future prospects of artificial ligaments for treating ACL injuries

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

14 Mar 2025

Study shows how autism-linked picky eating causes serious vitamin deficiencies

Children with autism spectrum disorder (ASD) face a high risk of multiple micronutrient deficiencies, especially vitamins A, D, B12, and calcium, due to extreme food selectivity. These deficiencies can lead to severe health issues like rickets, vision loss, and immune dysfunction, even in children with normal body weight.

13 Mar 2025

Already approved drug avapritinib shows promise in treating high-grade gliomas

High-grade glioma, an aggressive form of pediatric and adult brain cancer, is challenging to treat given the tumor location, incidence of recurrence and difficulty for drugs to cross the blood-brain barrier.

13 Mar 2025

Combination immunotherapy improves treatment response for head and neck cancer

Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherapy drug.

13 Mar 2025

Study uncovers new insights into pain pathways linked with temporomandibular joint disorders

A groundbreaking study has uncovered new insights into the pain pathways associated with temporomandibular joint (TMJ) disorders.

13 Mar 2025

Current PSA monitoring guidelines may lead to overtreatment after prostate surgery

After surgical removal of the prostate to treat prostate cancer, clinicians monitor Prostate Specific Antigen (PSA) levels.

13 Mar 2025

Hospital gun-violence prevention programs may be caught in US funding crossfire

Seven years ago, Erica Green learned through a Facebook post that her brother had been shot.

13 Mar 2025

Innovative gel prevents post-surgery adhesions in animal models

Surgical adhesions - common, sometimes life-threatening complications that arise after open or laparoscopic abdominal surgery - can be prevented in mice and pigs by a gel impregnated with a molecule that blocks a key signaling pathway in the formation of scar tissue.

12 Mar 2025

New technique effectively identifies aggressive medulloblastoma

Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma-the most common type of malignant brain tumour in children-and potentially sparing young patients from unnecessary treatments and their harmful long-term side effects.

12 Mar 2025

Examining skin cancer risk perceptions and reported sunburns among U.S. adults

Skin cancer is the most common cancer in the United States and a significant health issue, with millions of non-melanoma cases and tens of thousands of melanomas diagnosed annually. Furthermore, treating skin cancer costs the U.S. approximately $8.9 billion annually.

12 Mar 2025