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Biocompatibles, Philips to develop new treatment protocol for trans-arterial embolization

Royal Philips Electronics and Biocompatibles, a BTG international group company, announced a collaboration to advance the use of image guidance to control the delivery of beads during the arterial embolization of hypervascularized tumors today at the annual CIRSE (Cardiovascular and Interventional Radiological Society of Europe) meeting.

15 Sep 2012

CINJ experts available to discuss prevention and treatment of breast cancer

The Cancer Institute of New Jersey (CINJ) is making experts available to discuss the risks, and options for treatment and prevention surrounding breast cancer. According to the American Cancer Society 227,000 women nationwide will be diagnosed with the disease this year, and while the disease affects mostly women, men also can be diagnosed with breast cancer.

15 Sep 2012

Objective response rate promising after crizotinib for NSCLC

More than half of the latest evaluated participants from the ongoing phase II PROFILE 1005 trial of crizotinib against ALK-positive advanced non-small-cell lung cancer, achieved an objective tumor response, report researchers.

14 Sep 2012

Genomes of lung cancer smokers have more mutations

Lung cancer patients with a history of smoking have 10 times more genetic mutations in their tumors than those with the disease who have never smoked, according to a new study from Washington University School of Medicine in St. Louis.

14 Sep 2012

UMass Amherst develops 'chemical nose' array to detect metastatic cancers

In the fight against cancer, knowing the enemy's exact identity is crucial for diagnosis and treatment, especially in metastatic cancers, those that spread between organs and tissues. Now chemists led by Vincent Rotello at the University of Massachusetts Amherst have developed a rapid, sensitive way to detect microscopic levels of many different metastatic cell types in living tissue. Findings appear in the current issue of the journal ACS Nano.

14 Sep 2012

HIF-1a protein of hypoxia creates CD24 overexpression in many tumors

It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, is in fact linked with more aggressive tumor behavior and poorer prognosis.

14 Sep 2012

University of Central Florida professor receives NIH’s New Innovator award

The National Institutes of Health today awarded University of Central Florida Professor Ming Su its coveted New Innovator award, which comes with a $2 million grant.

14 Sep 2012

Senesco initiates SNS01-T cohort 2 trial in multiple myeloma

Senesco Technologies, Inc. reported today that the first patient has been enrolled and dosing has been initiated in cohort 2 of its clinical trial with SNS01-T in multiple myeloma.

14 Sep 2012

Optimal approach for esophageal cancer surgery varies

Accurate preoperative staging of junctional adenocarcinoma of the esophagus can impact the surgical approach used, and postoperative outcomes vary according to the patients’ stage of disease, report German researchers.

13 Sep 2012

Gefitinib shows promise in Chinese lung cancer patients

Gefitinib improves progression-free survival, overall response, and health-related quality of life over carboplatin/paclitaxel for first-line advanced non-small-cell lung cancer treatment, a study indicates.

13 Sep 2012

Platinum tissue concentrations predict NSCLC treatment response

Reduced tissue platinum accumulation might explain why some patients with non-small-cell lung cancer fail to respond to platinum-based chemotherapy, research shows.

13 Sep 2012

Crizotinib may be effective treatment option for NSCLC subtype

Phase I trial results show that the chemotherapy drug crizotinib may be fast-acting and produce long-lasting treatment responses in patients with anaplastic lymphoma receptor tyrosine kinase-positive non-small-cell lung cancer.

13 Sep 2012

Solubilized curcumin shrinks lung tumors in mice

Belgian researchers report that orally administered curcumin can reduce the size of lung cancer tumors in mice.

13 Sep 2012

Addition of sorafenib to chemotherapy does not prolong survival

The addition of sorafenib to gemcitabine/cisplatin fails to provide any additional benefit in chemotherapy-naïve patients with nonsquamous non-small-cell lung cancer, research shows.

13 Sep 2012

FDG–PET/CT improves staging and modifies radiotherapy management

The addition of FDG–positron emission tomography/computed tomography revised radiotherapy decision-making and enhanced tumor staging capabilities in patients with non-small-cell lung cancer, research shows.

13 Sep 2012

Changes in physical characteristics of regulatory T cell can predict MDS progression risk

Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) to acute myeloid leukemia. The finding could improve prognostication for patients with MDS and better inform therapeutic decision making.

13 Sep 2012

World experts shed light on the extent of dangers of night-time artificial lighting

"The most important thing for us is to raise awareness of the dangers of artificial light at night and we have already come a long way now that the American Medical Association (AMA) recently announced its new policy recognizing adverse health effects of exposure to light at night and encouraging further research into the matter," said Prof. Abraham Haim, a leading authority on light pollution, who coordinated the 21st International Congress of Zoology (ICZ) that was held last week at the University of Haifa, Israel.

12 Sep 2012

Data from Oncolytics’ REOLYSIN Phase III combination trial on head and neck cancers

Oncolytics Biotech Inc. today provided an update on its Phase III trial of REOLYSIN in combination with carboplatin and paclitaxel for the treatment of head and neck cancers (REO 018).

12 Sep 2012

Bioengineers design nanoparticles that can safely and predictably infiltrate deep into the brain

The brain is a notoriously difficult organ to treat, but Johns Hopkins researchers report they are one step closer to having a drug-delivery system flexible enough to overcome some key challenges posed by brain cancer and perhaps other maladies affecting that organ.

12 Sep 2012

Mount Sinai scientists identify cancer’s Achilles heel

Scientists at Mount Sinai School of Medicine have discovered a subpopulation of cells that display cancer stem cell properties and resistance to chemotherapy, and participate in tumor progression. This breakthrough could lead to the development of new tests for early cancer diagnosis, prognostic tests, and innovative therapeutic strategies, as reported in Cancer Cell.

11 Sep 2012