Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

Through a recent platform demonstration project, LabGenius’ machine learning-driven lead optimisation capability delivered dozens of novel T-cell engagers with best-in-class killing selectivity.

From LabGenius 16 May 2023

Study identifies two novel highly pathogenic avian influenza viruses (H5N1) clade 2.3.4.4b.2

Researchers investigated the genetic origin, distribution patterns, and antigenicity of novel AIVs.

16 May 2023

Insights from blood donors: Serosurveillance reveals population insights for targeted health interventions

Research highlights the effectiveness of serosurveillance in monitoring SARS-CoV-2 exposure within a population. It emphasizes the importance of considering demographic variations in antibody prevalence to inform targeted public health strategies.

16 May 2023

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma.

15 May 2023

Obesity undermines COVID-19 vaccines

Researchers examine the impact of obesity on COVID-19 outcomes and the effectiveness of vaccines in individuals with obesity. Using data from Scotland, the study explores the relationship between body mass index (BMI) and hospitalization/mortality due to COVID-19.

15 May 2023

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Announcing a new article publication for BIO Integration journal. Antibody-drug conjugates (ADCs) have the following advantages: target specificity; wide therapeutic index; and prolonged circulation half-life.

15 May 2023

Study indicates that the Omicron wave and the rollout of vaccines led to almost 100% seropositivity and boosted anti-spike IgG titers in children and adolescents

Researchers discussed the presence of persistent humoral immunity among children and adolescents during COVID-19.

15 May 2023

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

Researchers longitudinally isolated immensely potent monoclonal antibodies from macaques vaccinated with COVID-19.

12 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

People with obesity may need more frequent booster vaccines to maintain their immunity

The protection offered by COVID-19 vaccination declines more rapidly in people with severe obesity than in those with normal weight, scientists at the Universities of Cambridge and Edinburgh have found.

11 May 2023

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Research compares the durability of neutralizing antibody responses among recipients of three different COVID-19 vaccines (BNT162b2, mRNA-1273, and Ad26.COV2.S) over a period of 6 months.

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

New SNAP approach to customizing T cell-based immunotherapies

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other immunotherapies for treating cancer and other diseases.

9 May 2023

Concomitant tuberculosis disease significantly impacts HIV immune responses in people with HIV

New research from Boston Medical Center found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody resistant as compared to those without suspected or documented tuberculosis.

9 May 2023

Antibody News and Research

Further Reading

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

Study identifies two novel highly pathogenic avian influenza viruses (H5N1) clade 2.3.4.4b.2

Insights from blood donors: Serosurveillance reveals population insights for targeted health interventions

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

Obesity undermines COVID-19 vaccines

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Study indicates that the Omicron wave and the rollout of vaccines led to almost 100% seropositivity and boosted anti-spike IgG titers in children and adolescents

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

Targeting the hemoglobin problem in sickle cell disease using a new drug

People with obesity may need more frequent booster vaccines to maintain their immunity

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

New SNAP approach to customizing T cell-based immunotherapies

Concomitant tuberculosis disease significantly impacts HIV immune responses in people with HIV

UCF researcher develops a new, more precise treatment for acute respiratory viral infections

SARS-CoV-2 infection leads to higher IgA levels in breast milk than vaccination

Novel Rutgers vaccine may provide more durable protection against SARS-CoV-2

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Omicron's grip on Sweden: High transmission rates persist despite high seroprevalence

New approach addresses the challenge of directly connecting genetic variants to human traits, health

Using single B cell screening to boost antibody discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo