immunity News and Research

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Insilico Medicine to present scientific data on novel anti-cancer assets at major cancer conferences

Clinical stage artificial intelligence (AI) drug discovery company Insilico Medicine ("Insilico") has been invited to present scientific data on its novel anti-cancer assets at three major upcoming cancer conferences -- the European Society for Medical Oncology (ESMO) conference in Madrid Oct. 20-24, 2023; the Society of Immunotherapy of Cancer (SITC) conference Nov. 1-5, 2023 in San Diego; and the San Antonio Breast Cancer Symposium (SABCS) Dec. 5-9, 2023.

16 Oct 2023

Live vaccinations found to be safe for pediatric organ transplant recipients

Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions, according to a new study published Oct. 12, 2023, in JAMA Network Open.

16 Oct 2023

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

The study explores the efficacy of variant-adapted COVID-19 booster vaccines, particularly against new strains like Omicron. It raises questions about the need for annual updates and the best technologies for long-term, durable immunity.

15 Oct 2023

New TB treatments tackle the disease without wrecking your microbiome

Researchers in a study published in The Lancet Microbe examined how various tuberculosis treatment regimens affect the respiratory microbiome. They found that certain treatments control tuberculosis effectively while minimally impacting the diversity and health of the respiratory microbiome.

15 Oct 2023

Are people with HIV at a higher risk of severe COVID-19 outcomes?

The research review indicates that people with HIV, especially those with low CD4 cell counts, face greater risks of severe COVID-19 outcomes and have suboptimal immune responses to SARS-CoV-2. Antiretroviral therapy aids in clearing infections, and a third vaccine dose reduces the risk of breakthrough infections among this population.

15 Oct 2023

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

New research helps explain why young children have lower rates of severe COVID-19 than adults. A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.

13 Oct 2023

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

In a recent review published in Immunity, researchers reviewed tumor-immunity cycle data.

13 Oct 2023

Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

Moderna's updated mRNA-1273.815 COVID-19 vaccine shows promising results in reducing symptomatic cases, hospitalizations, and deaths in high-risk and older adults in Germany. The study finds the vaccine to be more cost-effective and clinically beneficial than both no vaccination and Pfizer's XBB.1.5 BNT162b2 vaccine.

12 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Researchers have developed EVScape, a predictive tool that identifies which SARS-CoV-2 strains are most likely to evade host immunity. Utilizing a deep generative model and structural information, the tool offers early warning about viral variants, aiding in the timely development of effective vaccines and treatments.

12 Oct 2023

Is there an association between vitamin D deficiency and sepsis mortality?

The impact of deficient serum vitamin D levels on sepsis prognosis.

12 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.

12 Oct 2023

Could young blood be the key to reversing age-related cognitive decline?

Researchers at the University of Auckland identify platelet factor 4 (PF4) in young blood as a key player in reversing age-related cognitive decline in mice. The study offers a promising avenue for treating dementia-related conditions and enhancing brain function in aging populations.

11 Oct 2023

CT scan of the thymus reveals immune system aging

Thymus, a small and relatively unknown organ, may play a bigger role in the immune system of adults than was previously believed.

11 Oct 2023

New nanocapsule treatment boosts immune response against solid tumors

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.

11 Oct 2023

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

The intricate interactions between gut microbiota and drugs.

11 Oct 2023

New TB vaccination strategy could save hundreds of thousands of lives with HIV

Scientists at the University of Pittsburgh School of Medicine have discovered a tuberculosis (TB) vaccination strategy that could prevent the leading cause of death among people worldwide living with HIV.

10 Oct 2023

COVID-19 vaccine response lower in patients with lung conditions, study finds

Clinicians and researchers at National Jewish Health studied COVID vaccine effectiveness in patients with underlying lung conditions such as asthma, chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD).

10 Oct 2023

Protein antigen from a childhood vaccine can help refocus the body's immune system against cancer

A University of Massachusetts Amherst team has demonstrated in theory that a protein antigen from a childhood vaccine can be delivered into the cells of a malignant tumor to refocus the body's immune system against the cancer, effectively halting it and preventing its recurrence.

10 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

immunity News and Research

Insilico Medicine to present scientific data on novel anti-cancer assets at major cancer conferences

Live vaccinations found to be safe for pediatric organ transplant recipients

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

New TB treatments tackle the disease without wrecking your microbiome

Are people with HIV at a higher risk of severe COVID-19 outcomes?

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Is there an association between vitamin D deficiency and sepsis mortality?

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Could young blood be the key to reversing age-related cognitive decline?

CT scan of the thymus reveals immune system aging

New nanocapsule treatment boosts immune response against solid tumors

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

New TB vaccination strategy could save hundreds of thousands of lives with HIV

COVID-19 vaccine response lower in patients with lung conditions, study finds

Protein antigen from a childhood vaccine can help refocus the body's immune system against cancer

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

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