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IL-6 emerges as early sepsis indicator in high risk groups

A pioneering study presented today at ESCMID Global 2025 has uncovered the potential of interleukin-6 (IL-6) as a powerful diagnostic biomarker for the early detection of sepsis in high-risk patient groups, including neonates, children and pregnant women.

11 Apr 2025

Northwestern scientists identify key genes behind Parkinson's development

A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also carry such variants do not.

11 Apr 2025

Boosting tumor-infiltrating lymphocyte therapy with the power of B cells

Researchers at Moffitt Cancer Center have found that tapping into the body's own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy.

11 Apr 2025

Bacteria engineered for remote sensing through color signatures

Bacteria can be engineered to sense a variety of molecules, such as pollutants or soil nutrients. In most cases, however, these signals can only be detected by looking at the cells under a microscope or similarly sensitive lab equipment, making them impractical for large-scale use.

11 Apr 2025

COVID-19 treatments show minimal serious side effects

Numerous treatment options for COVID-19 have been approved by the U.S. Food and Drug Administration over the last four years, including antiviral drugs and monoclonal antibodies that suppress an excessive immune response.

11 Apr 2025

GSK3β identified as a driver of drug resistance in BRAF mutant melanoma

A new research perspective was published in Oncotarget, Volume 16, on April 4, 2025, titled "GSK3β activation is a key driver of resistance to Raf inhibition in BRAF mutant melanoma cells."

11 Apr 2025

New assay detects epigenetic changes caused by carcinogenic chemicals

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard.

10 Apr 2025

Researchers explore drug repurposing strategy for Parkinson's disease

Despite significant advances in Parkinson's disease (PD) treatment, it remains incurable, with limited therapeutic options.

10 Apr 2025

Exploring the complex association between anemia and retinopathy of prematurity

Anemia is a common condition in premature infants, particularly those at risk for retinopathy of prematurity (ROP).

10 Apr 2025

Unlocking the power of MDA5 protein modifications in antiviral defense

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.

10 Apr 2025

Epigenetic discovery offers hope for reducing addiction relapse

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and thereby the formation of strong drug-related memories, which can trigger relapse in individuals with substance use disorders (SUDs).

10 Apr 2025

AI-driven personalized nutrition shows promise in improving gut health

Researchers examine the impact of AI-based personalized nutrition programs on the gut microbiome of healthy individuals.

10 Apr 2025

Certain nasal bacteria could affect COVID-19 vulnerability

A new study from researchers at the George Washington University has found that certain bacteria living in the nose may influence how likely someone is to get a COVID-19 infection.

9 Apr 2025

Study shows minimal lean muscle mass loss with GLP-1 and GLP-1/GIP therapy for weight loss

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that patients using GLP-1 or combined GLP-1 / GIP receptor agonist therapy for weight loss experienced minimal lean muscle mass loss as they lost weight across 6 months of treatment.

9 Apr 2025

Study explores impact of parental Alzheimer’s on tau protein spread in the brain

While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied to a greater spread of the tau protein in the brain that is a sign of the disease, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

9 Apr 2025

UCLA study identifies key protein driving kidney scarring

New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a potential precision medicine approach to prevent chronic kidney disease progression.

9 Apr 2025

Protein linked to Parkinson's also found to drive melanoma growth

A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, new research led by Oregon Health & Science University finds.

9 Apr 2025

Eating ultra-processed foods may rewire your brain’s hunger and reward circuits

High intake of ultra-processed foods is linked to adverse metabolic health and microstructural brain changes in regions that control appetite and reward. These effects occur both through obesity-related pathways and independently via inflammation and dyslipidemia.

9 Apr 2025

ETH Zurich researchers identify redundancies between the genes involved in DNA repair

Researchers aThe DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information.t ETH Zurich have unraveled the complex network that cells use to repair their genetic material.

9 Apr 2025

Menstrual cycle may drive inflammation in women with sickle cell disease

A marker linked to inflammation, C-reactive protein, may increase significantly during the follicular phase of the menstrual cycle in female patients with sickle cell disease (SCD), according to emerging research published today in Blood Vessels, Thrombosis & Hemostasis.

9 Apr 2025