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New understanding on Gleevec's limitations

University of Michigan researchers have developed an animal model that provides strong evidence why imatinib, marketed as Gleevec, helps patients with chronic myeloid leukemia survive longer, but does not keep the disease from returning if treatment ends.

4 Aug 2009

Clinical trial to test gene therapy for Alzheimer’s disease

Researchers at the Shiley-Marcos Alzheimer's Disease Research Center at the University of California San Diego are about to launch a Phase 2 clinical trial to test a gene therapy treatment for Alzheimer’s disease (AD) called CERE-110.

4 Aug 2009

Discovery of potential candidate protein for cancer vaccines

Researchers at the University of Pittsburgh School of Medicine have learned that some healthy people naturally developed an immune response against a protein that is made in excess levels in many cancers, including breast, lung, and head and neck cancers. The finding suggests that a vaccine against the protein might prevent malignancies in high-risk individuals.

4 Aug 2009

Accelerating the development of new cancer drugs

A phase I clinical trial enrolled its first patient only two days after U.S. Food and Drug Administration clearance of the experimental drug for a first-in-human cancer trial, a milestone that normally takes three to six months. Investigators from The University of Texas M. D. Anderson Cancer Center and pharmaceutical company AstraZeneca have reported their work in the Journal of Clinical Oncology published online on August 3rd.

4 Aug 2009

New method selectively kills metastatic melanoma

An international team of researchers has identified a new method for selectively killing metastatic melanoma cells, which may lead to new areas for drug development in melanoma – a cancer that is highly resistant to current treatment strategies.

4 Aug 2009

Selective method kills metastatic melanoma cells

An international team of researchers has identified a new method for selectively killing metastatic melanoma cells, which may lead to new areas for drug development in melanoma - a cancer that is highly resistant to current treatment strategies.

3 Aug 2009

Gene therapy for retinitis pigmentosa

An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease.

31 Jul 2009

Surgical treatment of migraine safe and effective

Migraine headaches are a drain - not only on the estimated 30 million Americans who suffer from them, but on the economy, too. Because pain and other symptoms caused by migraine headaches can be quite severe, it is projected that nearly $13 billion is spent every year in headache treatment and loss of time from work, which no one can afford these days.

31 Jul 2009

Study of pulmonary hypertension treatment in sickle cell patients stopped by NHLBI

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial testing a drug treatment for pulmonary hypertension in adults with sickle cell disease nearly one year early due to safety concerns.

28 Jul 2009

Seattle Genetics starts Brentuximab Vedotin retreatment trial

Seattle Genetics, Inc. has announced that it has initiated a phase II clinical trial of brentuximab vedotin (SGN-35), an antibody-drug conjugate (ADC), for the retreatment of patients with Hodgkin lymphoma and systemic anaplastic large cell lymphoma (ALCL).

27 Jul 2009

Improving patients' attention after a stroke could help them recover their motor skills

Scientists in New Zealand say after a stroke improving patients' attention could help them to recover their motor skills.

27 Jul 2009

Improving impaired attention may help patients recover from stroke

It may be possible to improve impaired attention after stroke - which could aid recovery - according to research reported in Stroke: Journal of the American Heart Association.

26 Jul 2009

Prevention, vaccines addressed at IAS conference

During the 5th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention meeting in Cape Town, South Africa, scientists "renewed the call for more immediate and urgent effort to be directed towards HIV prevention amid the dominance of treatment interventions and the world-wide search for a quick fix vaccine, which many agree, is years away," Health-e/allAfrica.com reports (Thom, 7/22).

22 Jul 2009

Altering the course of schizophrenia with new research

The National Institute of Mental Health (NIMH) is launching a large-scale research project to explore whether using early and aggressive treatment, individually targeted and integrating a variety of different therapeutic approaches, will reduce the symptoms and prevent the gradual deterioration of functioning that is characteristic of chronic schizophrenia.

21 Jul 2009

South Africa launches HIV/AIDS vaccine trial

"The first clinical trial of an HIV/AIDS vaccine designed and developed in South Africa was launched in Cape Town" Monday, the SAPA/The Times reports.

20 Jul 2009

Preliminary findings in Phase IIA trial point to natural compound NIC5-15's potential in Alzheimer's disease

Researchers at Mount Sinai School of Medicine have found that a compound called NIC5-15, might be a safe and effective treatment to stabilize cognitive performance in patients with mild to moderate Alzheimer's disease.

19 Jul 2009

Swine flu warning issued to pregnant women

Health officials are warning pregnant women to be extra careful in the midst of the current swine flu pandemic after three pregnant patients in New South Wales are in intensive care after contracting the novel H1N1 influenza virus.

16 Jul 2009

'Unstoppable Swine flu' and how to deal with it

Health authorities worldwide are preparing for what the World Health Organisation (WHO) has termed the 'unstoppable' spread of the new A/H1N1 virus (swine flu) for which Dr. Margaret Chan, Director-General of WHO, says a vaccine will not be available for several months to come.

15 Jul 2009

Results from trials of DHA in Alzheimer's and age-related cognitive decline

Results from two large studies using DHA, an omega 3 fatty acid, were reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.

12 Jul 2009

Flavonoids offer dementia, Alzheimer's hope

A group of chemicals found in many fruits and vegetables, as well as tea, cocoa and red wine, could protect the brain from Alzheimer's disease, a dementia expert told scientists at a conference last Friday.

12 Jul 2009