Protein C News and Research

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Microbiome search-based method can improve efficiency in disease detection and diagnosis

Big data makes big promises when it comes to providing insights into human behavior and health. The problem is how to harness the information it provides in an efficient manner.

23 Mar 2020

Melinjo seed extract may improve obesity and diabetes

In Southeast Asia, the fruit, flowers, and leaves of Indonesia's "Melinjo" tree are traditional foods.

23 Mar 2020

Changes in 3D genetic structure equally important as DNA code mutations in childhood leukemia

A study found that children with aggressive blood cancers have different superstructures of the proteins that control gene access.

23 Mar 2020

Study sheds light on myelin's role in 'chemobrain' and multiple sclerosis

Scientists have discovered that myelin is not as metabolically inert as has previously been thought.

23 Mar 2020

Research may help older adults maintain skeletal muscle mass and physical function for longer

Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria.

22 Mar 2020

A review of the literature on acute promyelocytic leukemia

Oncotarget Volume 11, Issue 11 reported that relapsed APL, particularly in the high-risk subset of patients, remains an important clinical problem.

22 Mar 2020

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Oncotarget Volume 11, Issue 11 reported that in order to understand the molecular mechanism of the dependency in MM, the research team examined gene expression changes upon DOT1L inhibition in sensitive and insensitive cell lines and discovered that genes belonging to the endoplasmic reticulum stress pathway and protein synthesis machinery were specifically suppressed in sensitive cells.

22 Mar 2020

Lance Liotta receives $72,000 for collaborative project

Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, received $72,000 from Queensland University of Technology for the project: "The Systems Biochemistry of Adaptation in Cellular Protein Networks." Australian Research Council Future Fellowship (total $784,680).

22 Mar 2020

Researchers decode 3D architecture of SARS-CoV-2 main protease

Teams around the world are working hard to develop active substances against SARS-CoV-2. The structural analysis of functional proteins of the virus is very helpful for this goal. The function of a protein is closely related to its 3D architecture.

21 Mar 2020

CNIC scientists identify inflammatory regulatory circuit controlled by endothelial cells in the eye

Researchers at the Centro Nacional de Investigaciones Cardiovasculares, working with an international network of scientists, have identified an inflammatory regulatory circuit in the eye controlled by a subtype of endothelial cells, the cells that line the interior of blood vessels.

21 Mar 2020

Scientists identify new role of important factor in early embryonic development

In collaboration with Stanford University, a working group from MedUni Vienna’s Division of Cell and Developmental Biology, led by Mark Wossidlo, has identified the role of a factor involved in early embryonic development.

20 Mar 2020

Avantor launches new Protein A Chromatography Resin – PROchievA – that provides supply chain flexibility and improves downstream purification performance for monoclonal antibodies (mAbs) production

Avantor, Inc., a leading global provider of mission-critical products and services to customers in the life sciences, advanced technologies and applied materials industries, today announced a new recombinant Protein A affinity chromatography resin used to purify antibodies during mAbs production.

From Avantor 20 Mar 2020

World’s fastest supercomputer identifies chemicals with potential to stop COVID-19

What makes the coronavirus disease (COVID-19) global pandemic different from the Spanish flu in 1918? In 1918, transportation, technology, and science were in their infancy, with the medical field not capable of fighting outbreaks. Technology has come a long way, within days, scientists have already identified the type of virus spreading in China, and three months after, vaccine trials have started.

20 Mar 2020

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Up to $2.86M has been awarded to a research team including Penn State scientists to develop a new oral antibiotic to treat multidrug-resistant gonorrhea, a sexually transmitted disease caused by bacteria that have developed resistance to all but one existing antibiotic.

20 Mar 2020

Researchers produce fat busting proteins in the lab

Triglycerides, those fats that seem to be the bane of any diet, remain a mystery for many researchers. Plenty of them are in Big Macs, deep pan pizza and the like, but some are a necessity to fuel the body for daily activities.

19 Mar 2020

How to slow down age-related changes?

Healthy aging has become one of the priorities of research in Europe. University of Tartu researchers looked for differences in the immune systems of young and old people.

19 Mar 2020

Diet affects sperm and the health of offspring

A new study published in the journal Molecular Cell, in March 2020, reports that parental diet is a crucial factor in the future metabolic health of the offspring.

19 Mar 2020

Research may pave the way to developing effective treatments for puerperal sepsis

Puerperal sepsis, also known as childbed fever, is the leading cause of maternal deaths. In this novel study in The American Journal of Pathology, published by Elsevier, scientists report on the discovery of group A streptococcus (GAS) surface proteins involved in female reproductive tract infections such as puerperal sepsis that may pave the way to developing vaccines and more effective treatments.

19 Mar 2020

Revolutionary technology could help identify more effective cancer drug combinations

A revolutionary new technology has been applied to reveal the inner workings of individual cancer cells - potentially identifying more effective treatment combinations for people with cancer.

19 Mar 2020

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team led by researchers at the RIKEN Cluster for Pioneering Research have identified a key player and the molecular events underlying this phenomenon in mice.

19 Mar 2020

Protein C News and Research

Microbiome search-based method can improve efficiency in disease detection and diagnosis

Melinjo seed extract may improve obesity and diabetes

Changes in 3D genetic structure equally important as DNA code mutations in childhood leukemia

Study sheds light on myelin's role in 'chemobrain' and multiple sclerosis

Research may help older adults maintain skeletal muscle mass and physical function for longer

A review of the literature on acute promyelocytic leukemia

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Lance Liotta receives $72,000 for collaborative project

Researchers decode 3D architecture of SARS-CoV-2 main protease

CNIC scientists identify inflammatory regulatory circuit controlled by endothelial cells in the eye

Scientists identify new role of important factor in early embryonic development

Avantor launches new Protein A Chromatography Resin – PROchievA – that provides supply chain flexibility and improves downstream purification performance for monoclonal antibodies (mAbs) production

World’s fastest supercomputer identifies chemicals with potential to stop COVID-19

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Researchers produce fat busting proteins in the lab

How to slow down age-related changes?

Diet affects sperm and the health of offspring

Research may pave the way to developing effective treatments for puerperal sepsis

Revolutionary technology could help identify more effective cancer drug combinations

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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