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Researchers have succeeded in mapping the unique patterns of neural activity produced by a wide range of odors

Revealing these distinct - but often overlapping - patterns of neural activity represents a significant step in understanding how the brain translates complex signals from odorant receptors in the nose into odor perception in the brain, the researchers said.

26 May 2005

Study shows how COX-2 inhibitors lead to heart disease

University of Pennsylvania School of Medicine researchers have found additional evidence that may help explain how selective inhibitors of COX-2 might predispose individuals to heart disease and stroke.

26 May 2005

Anti-inflammatory protein annexin 1 may protect patients from the detrimental effects of severe inflammatory response syndrome

Severe inflammatory response syndrome, or SIRS, occurs when the body's response to an overwhelming infection becomes uncontrolled. The very immune response meant to clear the pathogen and its toxins actually causes damage to the host's own tissues when it goes into overdrive, releasing too many immune signals.

23 May 2005

Bone loss reduced by blocking body's cannabis-like substances

British scientists have discovered that blocking the action of cannabis-like substances produced naturally by the body can reduce bone loss and they hope this finding will lead to new drugs to treat osteoporosis and other bone diseases.

23 May 2005

WHO says world must prepare for bird flu pandemic

Reports of disturbing changes to the H5N1 virus circulating in Asia is causing great concern and has prompted the World Health Organization (WHO) to urge countries to prepare for a influenza pandemic.

22 May 2005

Bald men can blame mum!

Despite an enormous range of treatments, obscure lotions and tinctures there appears to be very few successful counter-measures for hair loss in men. Beginning with receding hairlines, every second man suffers from hair loss to some degree, and it has always been suspected that hereditary factors are important in causing hair loss.

22 May 2005

New polysaccharide may help combat multidrug resistance in cancer

In a recent study published in the Journal of Biological Chemistry, scientists report that a molecule previously thought to play a purely structural and inert role in cells is actually involved in multidrug resistance in cancer.

22 May 2005

New insight into the machinery cells use to internalize cell surface receptors

Using state of the art imaging technology a team from Yale School of Medicine has glimpsed one of the cell's most important 'nano-machines' in action. The work, performed in collaboration with English and French scientists, provides new insight into the machinery cells use to internalize cell surface receptors.

22 May 2005

Hypertension drug combination yields high rate of blood pressure control in hard-to-treat patients

The study, conducted at the University of Maryland School of Medicine and 118 other sites, was focused on bringing down systolic blood pressure, the top number in a blood pressure reading, which is the more difficult number to bring down.

18 May 2005

A drug that controls blood pressure and reduces heart risk also appears to protect against diabetes

In new results from the VALUE trial that pitted the drug valsartan against another blood pressure drug, amlodipine, the patients taking valsartan were found to have a 23 percent lower risk of developing diabetes during the four or more years of the study.

18 May 2005

Postmenopausal women who follow a low-fat diet have 24 percent less chance of a recurrence of breast cancer

The study by Rowan T. Chlebowski and colleagues at Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, involved 2,437 women aged 48 to 79 who were diagnosed with early stage breast cancer and were treated at several medical centers. All the women had the standard treatments such as surgery, radiation therapy, and chemotherapy and or tamoxifen therapy.

17 May 2005

New drug combination prevents breast cancer growth pre-surgery

A new type of drug originally developed for lung cancer can reduce the size of breast cancer tumours when taken in combination with other drugs.

17 May 2005

Gefitinib (Iressa) could reduce the size of breast cancer tumours

Giving women with early breast cancer a drug called gefitinib (Iressa) before surgery could reduce the size of their tumours, suggests a randomised trial published online today by The Lancet Oncology.

17 May 2005

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

A unique, targeted anti-cancer drug appears to show promise against neuroendocrine tumors-stubborn cancers that have traditionally responded poorly to chemotherapy, according to research findings announced at the 2005 Annual Meeting of the American Society of Clinical Oncology (ASCO).

17 May 2005

Valium puts humans and amoeba to sleep

Biologists at University of California, San Diego (UCSD) have discovered that the popular sedative Valium has similar effects on the social amoeba Dictyostelium discoideum as it does in humans. Their surprising finding that Valium, as well as a "natural Valium" molecule found in human brains, causes the social amoeba to enter a dormant or "sleep" phase, may provide new insights into how cells in higher organisms, including humans, communicate with each other.

16 May 2005

Scientists discover how excess body fat can lead to the onset of diabetes

One out of 12 people in the western world suffers from type 2 (adult onset) diabetes. Worldwide, 150 million people are diabetic and their numbers are expected to double in the next 20 years, a result of the growing obesity epidemic. Yet, the reasons for the strong correlation between excess body fat and diabetes have been puzzling researchers.

16 May 2005

More health benefits from green tea

Green tea appears to protect against cancer by affecting a "promiscuous" protein that pharmaceutical experts are already targeting in an effort to develop a new drug to stop the disease, scientists at the University of Rochester Medical Center have found.

16 May 2005

Hormone Replacement Therapy (HRT) has a beneficial impact on cardiovascular health in hypertensive postmenopausal women

Oral Hormone Replacement Therapy (HRT) seems to have a beneficial impact on cardiovascular health in hypertensive postmenopausal women, researchers reported at the American Society of Hypertension Twentieth Annual Meeting held in San Francisco.

16 May 2005

Zometa reduces bone loss in patients receiving breast cancer treatment

Data presented at the American Society of Clinical Oncology (ASCO) annual meeting in Orlando, Florida, demonstrate that Zometa (zoledronic acid), an intravenous bisphosphonate, was shown to inhibit bone loss in postmenopausal women treated with Femara (letrozole) in the adjuvant breast cancer setting (directly following surgery to prevent cancer recurrence).

16 May 2005

Molecule found in liver cells could explain a lot about the relationship between diet, lipid levels in blood, and atherosclerosis

A team of researchers at the University of Pennsylvania School of Medicine have made a discovery that a molecule found in liver cells is important in explaining the relationship between diet, lipid levels in blood, and atherosclerosis.

15 May 2005

Receptor News and Research

Researchers have succeeded in mapping the unique patterns of neural activity produced by a wide range of odors

Study shows how COX-2 inhibitors lead to heart disease

Anti-inflammatory protein annexin 1 may protect patients from the detrimental effects of severe inflammatory response syndrome

Bone loss reduced by blocking body's cannabis-like substances

WHO says world must prepare for bird flu pandemic

Bald men can blame mum!

New polysaccharide may help combat multidrug resistance in cancer

New insight into the machinery cells use to internalize cell surface receptors

Hypertension drug combination yields high rate of blood pressure control in hard-to-treat patients

A drug that controls blood pressure and reduces heart risk also appears to protect against diabetes

Postmenopausal women who follow a low-fat diet have 24 percent less chance of a recurrence of breast cancer

New drug combination prevents breast cancer growth pre-surgery

Gefitinib (Iressa) could reduce the size of breast cancer tumours

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

Valium puts humans and amoeba to sleep

Scientists discover how excess body fat can lead to the onset of diabetes

More health benefits from green tea

Hormone Replacement Therapy (HRT) has a beneficial impact on cardiovascular health in hypertensive postmenopausal women

Zometa reduces bone loss in patients receiving breast cancer treatment

Molecule found in liver cells could explain a lot about the relationship between diet, lipid levels in blood, and atherosclerosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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