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New immunotherapy targets leukemia at its root

Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells – and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival.

14 Jul 2025

Sino Biological sets new industry standard with ProPure™ endotoxin-free proteins made in the USA

Sino Biological US, Inc. proudly unveils ProPure™, an industry-leading line of ultra-pure, endotoxin-free recombinant proteins, fully produced in the USA at its state-of-the-art Center for Bioprocessing (C4B) facility in Houston, Texas.

From Sino Biological Inc. 14 Jul 2025

How five months in Tibet changed the heart and lungs of Beijing workers

Long-term exposure to very high altitude significantly reduces cardiopulmonary function in healthy adults from lowland regions, as shown by declines in aerobic capacity and efficiency after five months in Lhasa, China.

13 Jul 2025

Study reveals dopamine sends precise signals rather than broad brainwide messages

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed.

12 Jul 2025

HPV16 and 18 nearly eliminated in vaccinated Danish women but other high risk types persist

Among the more than 100 types of human papillomavirus (HPV), at least 14 are considered as 'high-risk' types which can cause (cervical) cancer.

12 Jul 2025

Therapeutic potential of houttuynia cordata polysaccharide in H1N1 and MRSA-induced acute pneumonia

This new article publication from Acta Pharmaceutica Sinica B, discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.

12 Jul 2025

Stereotactic radiation shows promise for small cell lung cancer with brain metastases

A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they experienced positive outcomes that support use of targeted radiation in the future for such patients.

12 Jul 2025

Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131-TNF signaling pathway-mediated differentiation of immunosuppressive dendritic cells.

12 Jul 2025

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

This new article publication from Acta Pharmaceutica Sinica B, discusses how melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1.

12 Jul 2025

High-intensity focused ultrasound induces ferroptosis for tumor immune activation

This new article publication from Acta Pharmaceutica Sinica B, discusses high intensity forced ultrasound-driven ferroptosis as a strategy for anti-tumor immune priming.

12 Jul 2025

Composite HA-SF hydrogel provides natural and durable anti-aging solution

This new article publication from Acta Pharmaceutica Sinica B, discusses a high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers.

12 Jul 2025

New insights into how cells silence dangerous genomic elements

An international research team led by Freiburg biologists Dr. Wenjing Qi and Prof. Ralf Baumeister has discovered how the LINE1 retrotransposon exploits a cell protein to become active itself, as occurs in tumors.

12 Jul 2025

Uncovering the hidden architecture of the genome in three dimensions

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how stretches of DNA form genes, this oversimplification undersells the significance of the genome's 3D structure.

12 Jul 2025

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, represents a spectrum of liver disorders ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, and cirrhosis.

12 Jul 2025

Osteoblast estrogen receptor signaling found essential for bone integrity

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects bone health.

12 Jul 2025

Teclistamab shows promising results in heavily pretreated multiple myeloma

Teclistamab-cqyv (Tecvayli) led to clinically meaningful responses in patients with heavily pretreated multiple myeloma who would have been ineligible for the MajesTEC-1 trial, and identified a novel factor independently associated with outcomes.

12 Jul 2025

Scientists identify key role of T-bet in flu memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.

11 Jul 2025

More than 200 types of misfolded proteins could be associated with age-related cognitive decline

For decades, the story of Alzheimer's research has been dominated by a battle between A-beta and tau amyloids, both of which can kill neurons and impact the brain's ability to function.

11 Jul 2025

Scientists uncover key role of cypin in strengthening brain cell connections

Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for learning and memory.

11 Jul 2025

Erin Schuman wins 2026 HFSP Nakasone Award for neuroscience breakthrough

The International Human Frontier Science Program Organization (HFSPO) is pleased to award the 2026 HFSP Nakasone Award to Erin Schuman for her breakthrough related to the function and plasticity of neuronal synapses, their mRNA triggered function, and change during memory formation.

11 Jul 2025

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B Cell News and Research

New immunotherapy targets leukemia at its root

Sino Biological sets new industry standard with ProPure™ endotoxin-free proteins made in the USA

How five months in Tibet changed the heart and lungs of Beijing workers

Study reveals dopamine sends precise signals rather than broad brainwide messages

HPV16 and 18 nearly eliminated in vaccinated Danish women but other high risk types persist

Therapeutic potential of houttuynia cordata polysaccharide in H1N1 and MRSA-induced acute pneumonia

Stereotactic radiation shows promise for small cell lung cancer with brain metastases

Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

High-intensity focused ultrasound induces ferroptosis for tumor immune activation

Composite HA-SF hydrogel provides natural and durable anti-aging solution

New insights into how cells silence dangerous genomic elements

Uncovering the hidden architecture of the genome in three dimensions

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Osteoblast estrogen receptor signaling found essential for bone integrity

Teclistamab shows promising results in heavily pretreated multiple myeloma

Scientists identify key role of T-bet in flu memory B cells

More than 200 types of misfolded proteins could be associated with age-related cognitive decline

Scientists uncover key role of cypin in strengthening brain cell connections

Erin Schuman wins 2026 HFSP Nakasone Award for neuroscience breakthrough

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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