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Patients who develop AFib following TAVR have greater risk for complications

Patients developing AFib after TAVR are at higher risk of death, stroke and heart attack compared to patients who already had AFib prior to the procedure, according to a study today in JACC: Cardiovascular Interventions. The paper is the first nationwide examination of patients who developed AFib for the first time following TAVR.

3 Sep 2018

Likelihood of IVF success increases if 18 to 20 eggs are collected

The likelihood of childbirth after in vitro fertilization treatment increases if 18 to 20 eggs are stimulated to mature in a woman's ovaries, a dissertation at Sahlgrenska Academy, Sweden, shows. That is more eggs than the number aimed at in today's IVF treatments.

3 Sep 2018

Subcutaneous injection of new protein helps treat hemophilia more effectively

Patients with hemophilia bleed spontaneously or following trauma. The most common sites of bleeding are into joints, but bleeds can also happen into any tissue in the body including the muscles, brain, or eyes.

31 Aug 2018

Shionogi launches Mulpleta in the U.S for safe, effective treatment of thrombocytopenia

Shionogi & Co., Ltd. announced today that Mulpleta (lusutrombopag), a once-daily, orally administered, small molecule thrombopoietin (TPO) receptor agonist for the treatment of thrombocytopenia in adult patients with chronic liver disease (CLD) who are scheduled to undergo a procedure, is now available throughout the United States.

30 Aug 2018

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration accepted its supplemental Biologics License Application for Sprycel (dasatinib) in combination with chemotherapy for the treatment of pediatric patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.

30 Aug 2018

Californians living longer with cancer — some longer than others

As he grew older, Dale Kunitomi paid closer attention to his health — and to his doctor's advice. When he noticed rectal bleeding in 2010, he went to see his physician, who ordered a colonoscopy.

30 Aug 2018

New trial assesses criteria used to diagnose myocardial infarction

Results of the first randomized trial testing the criteria used to diagnose heart attack are presented today in a Hot Line Session at ESC Congress 2018 and published in The Lancet.

28 Aug 2018

Tips to know your ovarian cancer risk and symptoms

Ovarian cancer is the fifth leading cause of death in American women, according to the American Cancer Society, and accounts for more deaths than any other cancer of the female reproductive system. And according to the National Cancer Institute, approximately 22,240 women will be diagnosed with the disease in 2018; 14,070 will die from it.

28 Aug 2018

Major bleeding associated with subsequent cancer diagnoses

Bleeding in patients treated with anticoagulants should stimulate a search for cancer, according to late breaking results from the COMPASS trial presented today at ESC Congress 2018.

28 Aug 2018

Combined oral anticoagulant and antiplatelet therapy linked to poor prognosis in atrial fibrillation

Combined oral anticoagulant and antiplatelet therapy is associated with a worse prognosis than anticoagulation alone in newly diagnosed atrial fibrillation patients without a clear indication for antiplatelets, according to late breaking results from the GARFIELD-AF registry presented today at ESC Congress 2018.

28 Aug 2018

Drug coated balloons are as good as stent implants for treating small blocked arteries

A removable balloon is as good as a permanent stent implant for opening small blocked arteries, according to late breaking results from the BASKET-SMALL 2 trial presented in a Hot Line Session today at ESC Congress 2018 and simultaneously published in The Lancet.

28 Aug 2018

Daily use of aspirin does not reduce occurrence of major cardiovascular events, finds ARRIVE trial

The role of aspirin in preventing a first heart attack or stroke among people at moderate risk of heart disease remains unclear.

28 Aug 2018

Low dose Aspirin daily – benefits and risks measured in two studies

Low dose Aspirin has been advocated to reduce the risk of a second heart attack or a stroke or other heart problems in persons who have had one episode. A major new study published in the Lancet, has found that taking Aspirin to prevent the first heart attack fails to work. In fact the risks of taking low dose Aspirin to prevent the first heart attack outweigh the benefits.

27 Aug 2018

Antiplatelet monotherapy appears to be safer but does not reduce risk of heart attack

Long-term antiplatelet monotherapy after stenting is safe but does not reduce the risk of death or heart attack compared to standard dual antiplatelet therapy, according to late breaking results from the GLOBAL LEADERS trial presented today in a Hot Line Session at ESC Congress 2018 and published in The Lancet.

27 Aug 2018

Study finds main reasons why people die after noncardiac surgery

The main reasons why people die after noncardiac surgery are revealed today in a study of more than 40,000 patients from six continents presented in a late breaking science session at ESC Congress 2018.

27 Aug 2018

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

The antithrombin drug rivaroxaban does not reduce the risk of a composite endpoint of survival, myocardial infarction and stroke after an episode of worsening heart failure in patients with heart failure, sinus rhythm, and coronary artery disease, according to late breaking results from the COMMANDER HF trial presented today in a Hot Line Session at ESC Congress 2018 and with simultaneous publication in NEJM.

27 Aug 2018

Cardiovascular disease patients with internal bleeding more likely to be diagnosed with cancer

Patients with cardiovascular disease who develop major internal bleeding are much more likely to be diagnosed with cancer, a large international clinical trial has found.

27 Aug 2018

Aspirin appears to cause major bleeds and have no effect on cancers

Aspirin prevented serious vascular events in patients with diabetes who did not already have cardiovascular disease, but it caused almost as many major bleeds and there was no effect on cancers.

27 Aug 2018

Impaired mental status linked to doubled risk of death after heart attack in elderly patients

Impaired mental status is associated with a doubled risk of death one year after a heart attack in elderly patients, according to research presented today at ESC Congress 2018.

27 Aug 2018

Oral anticoagulant use after hospital discharge may offer protection from non-fatal blood clots

The use of an oral anticoagulant medicine in medically ill patients for 45 days following their discharge from the hospital reduces the rate of non-fatal symptomatic blood clots with no impact on fatal blood clots, according to late breaking results from the MARINER trial presented today in a Hot Line Session at ESC Congress 2018 and published in The New England Journal of Medicine.

27 Aug 2018

Bleeding News and Research

Patients who develop AFib following TAVR have greater risk for complications

Likelihood of IVF success increases if 18 to 20 eggs are collected

Subcutaneous injection of new protein helps treat hemophilia more effectively

Shionogi launches Mulpleta in the U.S for safe, effective treatment of thrombocytopenia

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Californians living longer with cancer — some longer than others

New trial assesses criteria used to diagnose myocardial infarction

Tips to know your ovarian cancer risk and symptoms

Major bleeding associated with subsequent cancer diagnoses

Combined oral anticoagulant and antiplatelet therapy linked to poor prognosis in atrial fibrillation

Drug coated balloons are as good as stent implants for treating small blocked arteries

Daily use of aspirin does not reduce occurrence of major cardiovascular events, finds ARRIVE trial

Low dose Aspirin daily – benefits and risks measured in two studies

Antiplatelet monotherapy appears to be safer but does not reduce risk of heart attack

Study finds main reasons why people die after noncardiac surgery

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

Cardiovascular disease patients with internal bleeding more likely to be diagnosed with cancer

Aspirin appears to cause major bleeds and have no effect on cancers

Impaired mental status linked to doubled risk of death after heart attack in elderly patients

Oral anticoagulant use after hospital discharge may offer protection from non-fatal blood clots

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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