Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Deactivating specific protein with drugs reverses inflammation, scarring of liver in NASH patients

A team of researchers led by Duke-NUS Medical School and National Heart Centre Singapore found that deactivating a specific protein - interleukin 11 - with drugs called therapeutic antibodies, reverses inflammation and scarring of the liver in patients suffering from an untreatable type of fatty liver disease called non-alcoholic steatohepatitis .

25 May 2019

Novel program that provides comprehensive care for Turner syndrome earns national recognition

A novel program designed to provide comprehensive care for Turner syndrome at The University of Texas Health Science Center at Houston and UT Physicians is one of the first in the U.S. to be designated an adult clinic by the Turner Syndrome Global Alliance.

24 May 2019

Drug routines of children with type 1 diabetes are disrupted during holidays

Children with type 1 diabetes find it difficult to adhere to their drug routines during school holidays and weekends.

23 May 2019

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Genetic variation in heart valve cells of the developing fetus create the blueprint for the later development of mitral valve prolapse, according to the cover story of today's Science Translational Medicine.

23 May 2019

Study discovers origin of neurofibromas that develop throughout the skin of NF1 patients

A study published today in PLOS ONE discovered the origin of severely disfiguring masses of cells, called neurofibromas, that gradually develop throughout the skin of patients afflicted with Neurofibromatosis 1.

22 May 2019

New algorithm guides catheters to accurately locate atrial fibrillation sources

Patients with atrial fibrillation or AFib experience chaotic electrical signals in the upper chamber of their heart (atria), which cause an irregular or quivering heartbeat (arrhythmia) that can lead to blood clots and heart failure. AFib also is a major cause of stroke and affects 33 million people worldwide.

21 May 2019

Research recommends prompt endoscopic removal when children swallow button batteries

Damage to the lining of the stomach can occur quickly when children swallow button batteries; therefore, clinicians should consider prompt endoscopic removal, even when the child is symptom free and the battery has passed safely through the narrow esophagus, according to research presented at Digestive Disease Week® (DDW) 2019.

20 May 2019

MDI Biological Laboratory receives $30,000 to support course in organoid technology

The MDI Biological Laboratory has announced that it has received more than $30,000 in cash and in-kind awards in support of its second annual "Applications of Organoid Technology" course, to be held May 26 through June 1 at the institution's Bar Harbor campus.

14 May 2019

British teenager with life-threatening infection successfully treated with phage therapy

Doctors report success after treating a British teenager with bacteriophages. The case study is a step forward in the fight against antibiotic resistance.

9 May 2019

Early clinical trial of new treatment for severe dry eye disease shows promising results

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a paper in Translational Vision Science and Technology.

7 May 2019

Experts to present tumor DNA, breast and jaw reconstruction studies at PSRC annual meeting

The Plastic Surgery Research Council focuses on awareness surrounding compelling research relating to the field of plastic surgery.

3 May 2019

Plastic surgeons and scientists develop synthetic soft tissue substitute with fewer side effects

A team of plastic surgeons and material scientists has made an important advance in treating the common clinical problem of soft tissue loss.

3 May 2019

Scientists enter research collaboration to find a cure for cancer

Cancer is a disease that afflicts an alarming number of people, with one in two being diagnosed with a type of cancer during their lifetime.

17 Apr 2019

Three studies show how tumors hijack the immune system to develop radiotherapy resistance

More than a decade ago, radiation oncologists noticed a nifty phenomenon: Sometimes radiation used locally against a tumor could excite the immune system to attack cancer systemically throughout the body.

17 Apr 2019

Study suggests new approach to treat renal fibrosis

Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure.

16 Apr 2019

Framingham Heart Study receives $38 million for the next six years

The Framingham Heart Study, the nation's longest running cohort study with longitudinal analysis of cardiovascular disease, has been renewed for an additional six years and $38 million dollars from the National Heart, Lung, and Blood Institute.

16 Apr 2019

Novel serum biomarkers to detect NAFLD-related fibrosis

With an estimated 25% of people worldwide affected by nonalcoholic fatty liver disease (NAFLD), there is a large unmet need for accurate, noninvasive measures to enhance early diagnosis and screening of hepatic fibrosis.

16 Apr 2019

Aldo-keto reductase family 1 member B10 enzyme found in advanced liver diseases

Nonalcoholic steatohepatitis is associated with liver inflammation in patients with nonalcoholic fatty liver disease, and it can progress to liver fibrosis at an advanced stage, and also to hepatocellular carcinoma and portal hypertension.

12 Apr 2019

EuroCMR 2019 to present novel studies on clinical use of cardiovascular magnetic resonance

Novel studies from around the world showing cutting-edge clinical use of cardiovascular magnetic resonance will be presented at EuroCMR 2019, a meeting of the European Association of Cardiovascular Imaging, a branch of the European Society of Cardiology.

10 Apr 2019

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

A group of researchers from the Centro de Investigación Biomédica en Red de Enfermedades Raras, Universidad Carlos III de Madrid, the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, and the Instituto de Investigación Sanitaria Fundación Jiménez Díaz have led a study which demonstrates the viability of a gene editing strategy for recessive dystrophic epidermolysis bullosa (also known as butterfly chilidren) with the tool CRISPR/Cas9 in preclinical models with this disease.

8 Apr 2019

Fibrosis News and Research

Further Reading

Deactivating specific protein with drugs reverses inflammation, scarring of liver in NASH patients

Novel program that provides comprehensive care for Turner syndrome earns national recognition

Drug routines of children with type 1 diabetes are disrupted during holidays

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Study discovers origin of neurofibromas that develop throughout the skin of NF1 patients

New algorithm guides catheters to accurately locate atrial fibrillation sources

Research recommends prompt endoscopic removal when children swallow button batteries

MDI Biological Laboratory receives $30,000 to support course in organoid technology

British teenager with life-threatening infection successfully treated with phage therapy

Early clinical trial of new treatment for severe dry eye disease shows promising results

Experts to present tumor DNA, breast and jaw reconstruction studies at PSRC annual meeting

Plastic surgeons and scientists develop synthetic soft tissue substitute with fewer side effects

Scientists enter research collaboration to find a cure for cancer

Three studies show how tumors hijack the immune system to develop radiotherapy resistance

Study suggests new approach to treat renal fibrosis

Framingham Heart Study receives $38 million for the next six years

Novel serum biomarkers to detect NAFLD-related fibrosis

Aldo-keto reductase family 1 member B10 enzyme found in advanced liver diseases

EuroCMR 2019 to present novel studies on clinical use of cardiovascular magnetic resonance

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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