Membrane News and Research

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New K+-sensitive dual-mode imaging probe for diagnosis of tumor malignancy

Tumor malignancy identification plays an essential role in clinical management of cancer. Currently, biopsy is the gold standard for malignancy identification in most tumor cases, it is, however, invasive that can cause great discomfort to patients, and potentially increase the risk of distant metastases due to the complex sampling process.

1 Jul 2022

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

Ischemic stroke risk may be higher after COVID-19 compared to flu or bacterial pneumonia

A new study examined electronic health records for approximately half the population of Denmark, looking for people with a diagnosis of COVID-19 or hospitalized with community-acquired pneumonia.

30 Jun 2022

Identification of potent SARS-CoV-2 macrodomain inhibitors

A recent study posted to the bioRxiv* preprint server illustrated the optimization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein 3 (NSP3) macrodomain (Mac) inhibitor based on structure.

30 Jun 2022

Investigating the prerequisites for developing RNA-based antibiotics

In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions of people against severe disease progression of COVID-19 or even death.

29 Jun 2022

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

The virus that causes COVID-19 undertakes a massive takeover of the body's fat-processing system, creating cellular storehouses of fat that empower the virus to hijack the body's molecular machinery and cause disease.

28 Jun 2022

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers performed genomic comparisons between alphacoronaviruses (αCoVs) and betacoronaviruses (βCoVs) originating from South Korean Bats.

28 Jun 2022

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

A recent study posted to the bioRxiv* preprint server assessed whether niclosamide could be employed in coronavirus disease 2019 (COVID-19) therapy.

28 Jun 2022

Lipid-peptide nanocomplexes offer new mRNA platform

A new paper reports the methodical development of lipid-peptide nanocomplexes as a delivery vehicle for messenger ribonucleic acid molecules to the tumor cell, in vitro and in vivo.

27 Jun 2022

Scientists create new fluorophores that could help fight cancer

Scientists from the Ural Federal University and the Ural Branch of the Russian Academy of Sciences have created new fluorescent chemical compounds (fluorophores) for photodynamic therapy of cancerous tumors, the latest method of treating cancer.

27 Jun 2022

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Researchers constructed a full-length SARS-CoV-2 spike structure in its membrane-bound state to study functionally relevant aspects of its global conformational dynamics.

27 Jun 2022

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Need another reason to think twice before ordering that extra helping of fries? It could lead to a higher risk of developing liver cancer.

24 Jun 2022

Researchers determine optimal conditions to perform impedance cytometry

Having a good eye for detail is an essential skill for many professions. In particular, biologists use special techniques and advanced technology to analyze individual cells with unprecedented precision.

24 Jun 2022

Associations between maternal COVID-19 vaccination and hospitalization among infants

Researchers assessed the efficacy of maternal mRNA vaccinations during pregnancy against hospitalization for COVID-19 in infants aged <6 months.

24 Jun 2022

Bacterium discovery helps to solve the puzzle of what factors limit cell size

On sunken leaves in the waters of a Caribbean mangrove swamp, researchers discovered a bacterium that challenges the prevailing view of bacterial cell size; counter to the notion that microbes are only visible with a microscope, this one – named Thiomargarita magnifica – is larger than all other known giant bacteria by ~50-fold, and can be seen by the naked eye, the study's authors say.

23 Jun 2022

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

Researchers at the John T. Macdonald Department of Human Genetics and John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families.

23 Jun 2022

Membrane News and Research

New K+-sensitive dual-mode imaging probe for diagnosis of tumor malignancy

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Ischemic stroke risk may be higher after COVID-19 compared to flu or bacterial pneumonia

Identification of potent SARS-CoV-2 macrodomain inhibitors

Investigating the prerequisites for developing RNA-based antibiotics

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

Lipid-peptide nanocomplexes offer new mRNA platform

Scientists create new fluorophores that could help fight cancer

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Researchers determine optimal conditions to perform impedance cytometry

Associations between maternal COVID-19 vaccination and hospitalization among infants

Bacterium discovery helps to solve the puzzle of what factors limit cell size

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

Researchers model a complex childhood disease on-a-chip

Scientists reveal mutational frequency in SARS-CoV-2 proteome based on structural characteristics

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo