Pathogen News and Research

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Containing a Nipah virus outbreak amidst the COVID-19 pandemic

A new study deals with a single case of Nipah virus that occurred in 2021, with no discoverable chain of transmission, apparently ending with the death of the index patient in Kerala.

15 Dec 2021

Eating before saliva collection may interfere with detection of SARS-CoV-2

A new study, published on the medRxiv* preprint server, has aimed to determine if children's diet impacts the detection of SARS-CoV-2 virus in saliva. Scientists performed diagnostic tests to detect this virus using real-time self-collected specimens provided by five healthy children. The samples were collected before and after eating selected foods. The specific time of collection of samples after eating were 0 minutes, 20 minutes, and 60 minutes after eating.

15 Dec 2021

Thrombosis may increase mortality risk in hospitalized COVID-19 patients

A team of US-based scientists has recently explored various risk factors associated with the poor prognosis of coronavirus disease 2019 (COVID-19). They have identified thrombosis-related risk factors as a major predictor of in-hospital COVID-19 related mortality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

14 Dec 2021

The evolution of SARS-CoV-2 variants during slow and fast epidemics

Researchers discuss an analytical framework to investigate the contribution of the transmissibility advantage SARS-CoV-2 variants.

14 Dec 2021

Duke Human Vaccine Institute secures federal contract for advancing investigational vaccines

The National Institute of Allergy and Infectious Diseases awarded researchers at the Duke Human Vaccine Institute a contract that enables it to compete for projects advancing investigational vaccines to production for use in early clinical trials.

14 Dec 2021

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but also emphasized the potential use of this technology towards developing effective molecular diagnostic platforms for any future pandemic.

13 Dec 2021

A model-based evaluation on the effectiveness of social distancing in COVID

Researchers utilize a mathematical model-based analysis to assess how social distancing measures contained the COVID-19 pandemic and reduced mortality.

13 Dec 2021

What are the implications of orangutan translocation risks in the COVID-19 era?

Can orangutan translocation pose infectious disease transmission and species conservation threats?

13 Dec 2021

Genetic-code expansion technique to potentially create next-generation vaccine candidate

A new experiment devised a novel method to manipulate virulent viruses in conventional laboratories and validated the prophylactic effect of this method in two mouse models.

13 Dec 2021

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

A team of researchers recently developed a statistical modeling method known as multiple-layer crosstalk (MLCrosstalk).

12 Dec 2021

A pandemic-scale phylogenetic analysis tool

Researchers develop a phylogenetic package that incorporated several pandemic-specific optimization and parallelization techniques.

12 Dec 2021

Infant immune system beats the adult immune system at fighting off new pathogens

As any parent knows, infants are prone to getting respiratory infections.

12 Dec 2021

Impact of environmental SARS-CoV-2 contamination in residential housing

In a new study, scientists hypothesize that the presence of Corynebacterium and SARS-CoV-2 in surface samples might be associated with skin contamination.

10 Dec 2021

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

New research posted to the medRxiv* preprint server suggests that the Agena MassARRAY SARS-CoV-2 Panel PCR test effectively detects a variety of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

9 Dec 2021

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

New study demonstrates that it is possible one day that breastmilk samples will be used to characterize broad mucosal immunity after vaccination.

8 Dec 2021

ORF10 protein mutations alter SARS-CoV-2 pathogenicity

Researchers examine 140 unique SARS-CoV-2 ORF10 sequences among 202,968 ORF10 retrieved sequences.

7 Dec 2021

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

New research reports 4’-Fluorouridine (4′-FlU) as an oral antiviral against RSV and SARS-CoV-2.

7 Dec 2021

Antibody response to COVID-19 vaccine may be affected by the body’s circadian rhythms

Our internal 24-hour circadian clock regulates many aspects of physiology, including the response to infectious disease and vaccination.

7 Dec 2021

New research reveals how Europeans evolved greater resistance against anthrax

New research from the Cornell College of Veterinary Medicine has revealed how humans evolved greater resistance against anthrax multiple times during history: when they developed a diet of more ruminants, and when agricultural practices took hold.

7 Dec 2021

Combination of prior infection and vaccination produces a more potent defense against SARS-CoV-2

Antibodies against the SARS-CoV-2 spike protein produced by the immune system can help identify and fend off future infections, but not all antibodies are the same.

7 Dec 2021

Pathogen News and Research

Containing a Nipah virus outbreak amidst the COVID-19 pandemic

Eating before saliva collection may interfere with detection of SARS-CoV-2

Thrombosis may increase mortality risk in hospitalized COVID-19 patients

The evolution of SARS-CoV-2 variants during slow and fast epidemics

Duke Human Vaccine Institute secures federal contract for advancing investigational vaccines

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A model-based evaluation on the effectiveness of social distancing in COVID

What are the implications of orangutan translocation risks in the COVID-19 era?

Genetic-code expansion technique to potentially create next-generation vaccine candidate

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

A pandemic-scale phylogenetic analysis tool

Infant immune system beats the adult immune system at fighting off new pathogens

Impact of environmental SARS-CoV-2 contamination in residential housing

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

ORF10 protein mutations alter SARS-CoV-2 pathogenicity

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

Antibody response to COVID-19 vaccine may be affected by the body’s circadian rhythms

New research reveals how Europeans evolved greater resistance against anthrax

Combination of prior infection and vaccination produces a more potent defense against SARS-CoV-2

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